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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004177naa a2200589 4500
001oai:gup.ub.gu.se/258917
003SwePub
008240528s2017 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/2589172 URI
024a https://doi.org/10.1093/ehjcvp/pvx0072 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Abell, J. E.4 aut
2451 0a Adjunctive use of anticoagulants at the time of percutaneous coronary intervention in patients with an acute coronary syndrome treated with fondaparinux: a multinational retrospective review
264 c 2017-04-18
264 1b Oxford University Press (OUP),c 2017
520 a Aim This retrospective chart review was designed to evaluate physician adherence to the prescribing information for fondaparinux regarding adjunctive anticoagulant use during percutaneous coronary intervention (PCI) in patients with an acute coronary syndrome (ACS). Methods and results Medical record abstractors at each site obtained information regarding the use of fondaparinux and adjunctive anticoagulants during PCI. Physician adherence to fondaparinux prescribing information regarding the administration of an adjunctive anticoagulant during PCI was estimated using generalized estimating equations. This retrospective study, conducted in 2008-2010, included a total of 1056 patient records from 27 sites across 6 countries (Canada, France, Germany, Greece, Poland, and Sweden). Over 98% of patients had been treated with fondaparinux at the recommended 2.5 mg dose. Use of adjunctive anticoagulant during PCI was 97.5%, giving an adjusted adherence rate of 98.8% (95% confidence interval: 0.97-0.99), with 86.3% of patients receiving unfractionated heparin. Although the sub-group of patients with ST-elevation myocardial infarction who underwent primary PCI was too small to make a definitive conclusion, 70.4% of the 159 patients did not receive fondaparinux immediately prior to (<24 h) or during primary PCI, suggesting that their treating physicians may have been adherent to the prescribing information. Conclusion Physician adherence to the prescribing information for adjunctive anticoagulation during PCI in patients with an ACS receiving fondaparinux was high. The results were consistent in each of the six countries and across patient sub-groups.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a Acute coronary syndrome
653 a Adherence
653 a Fondaparinux sodium
653 a Post-marketing surveillance
653 a elevation myocardial-infarction
653 a association task-force
653 a st-segment
653 a elevation
653 a practice guidelines
653 a american-college
653 a randomized-trial
653 a esc
653 a guidelines
653 a management
653 a adherence
653 a enoxaparin
653 a Cardiovascular System & Cardiology
700a Laing, S. M.4 aut
700a Barker, T. C.4 aut
700a Norry, E. C.4 aut
700a Starzyk, K.4 aut
700a Goodman, S. G.4 aut
700a Dellborg, Mikael,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xdelmi
700a Steg, P. G.4 aut
700a Giugliano, R. P.4 aut
710a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
773t European Heart Journal - Cardiovascular Pharmacotherapyd : Oxford University Press (OUP)g 3:4, s. 214-220q 3:4<214-220x 2055-6837x 2055-6845
856u https://academic.oup.com/ehjcvp/article-pdf/3/4/214/19785238/pvx007.pdf
8564 8u https://gup.ub.gu.se/publication/258917
8564 8u https://doi.org/10.1093/ehjcvp/pvx007

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