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Sökning: onr:"swepub:oai:gup.ub.gu.se/266265" > Twelve-lead electro...

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FältnamnIndikatorerMetadata
00003714naa a2200457 4500
001oai:gup.ub.gu.se/266265
003SwePub
008240528s2017 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/2662652 URI
0247 a https://doi.org/10.1177/23969873166847062 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Pirinen, Jani4 aut
2451 0a Twelve-lead electrocardiogram and mortality in young adults after ischaemic stroke
264 c 2016-12-14
264 1b SAGE Publications,c 2017
520 a Introduction: Ischaemic stroke at young age carries an increased risk for mortality in comparison to the general population, but factors associated with mortality have been poorly studied. We studied the role of electrocardiogram in mortality risk stratification in young stroke patients. Patients and methods: The Helsinki Young Stroke Registry encompasses 1008 patients aged <50 years with ischaemic stroke. We included 690 patients for this electrocardiogram substudy. Our endpoints were all-cause and cardiovascular mortality. Cox regression models – adjusted for clinical and demographic characteristics – were used to identify the electrocardiogram parameters associated with these endpoints. Results: At a mean follow-up of 8.8 years, cumulative all-cause and cardiovascular mortality were 16.1 and 9.1%, respectively. Factors associated with both endpoints included diabetes (type 1 for all-cause, type 2 for cardiovascular mortality), heavy drinking, malignancy, as well as stroke severity and aetiology. Of the electrocardiogram parameters, higher heart rate (hazard ratio 1.35 per 10/min, 95% confidence interval 1.21–1.49), a shorter P-wave (hazard ratio 0.78 per 10 ms decrement, 0.64–0.92) and longer QTc interval (1.09 per 10 ms, 1.03–1.16) were associated with increased all-cause mortality. Only a higher heart rate (1.42 per 10/min, 1.24–1.60) was associated with death from cardiovascular causes. Conclusions: A higher heart rate during the subacute phase after stroke is associated with an elevated risk of all-cause and cardiovascular mortality in young adults. A longer QTc interval is associated only with higher all-cause mortality. P-wave characteristics and their possible association with mortality need further studies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a Electrocardiogram
653 a stroke
653 a young stroke
653 a prognosis
653 a mortality
7001 a Putaala, Jukka4 aut
7001 a Aarnio, Karoliina4 aut
7001 a Aro, Aapo L4 aut
7001 a Mustanoja, Satu4 aut
7001 a Sinisalo, Juha4 aut
7001 a Kaste, Markku4 aut
7001 a Haapaniemi, Elena4 aut
7001 a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience4 aut0 (Swepub:gu)xtatlt
7001 a Lehto, Mika4 aut
7102 a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap4 org
7730 t European Stroke Journald : SAGE Publicationsg 2:1, s. 77-86q 2:1<77-86x 2396-9873x 2396-9881
8564 u https://journals.sagepub.com/doi/pdf/10.1177/2396987316684706
8564 8u https://gup.ub.gu.se/publication/266265
8564 8u https://doi.org/10.1177/2396987316684706

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