Sökning: onr:"swepub:oai:gup.ub.gu.se/271748" > A three-generation ...
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000 | 09424naa a2201021 4500 | |
001 | oai:gup.ub.gu.se/271748 | |
003 | SwePub | |
008 | 240528s2018 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-145740 | |
009 | oai:DiVA.org:uu-365986 | |
024 | 7 | a https://gup.ub.gu.se/publication/2717482 URI |
024 | 7 | a https://doi.org/10.1093/ije/dyy0312 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1457402 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3659862 URI |
040 | a (SwePub)gud (SwePub)umud (SwePub)uu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Accordini, S.u Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy4 aut |
245 | 1 0 | a A three-generation study on the association of tobacco smoking with asthma |
264 | c 2018-03-09 | |
264 | 1 | b Oxford University Press (OUP),c 2018 |
520 | a Background: Mothers' smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers' smoking may have a similar effect, and biological plausibility that fathers' smoking during adolescence may influence offspring's health through transmittable epigenetic changes in sperm precursor cells. We evaluated the three-generation associations of tobacco smoking with asthma. Methods: Between 2010 and 2013, at the European Community Respiratory Health Survey III clinical interview, 2233 mothers and 1964 fathers from 26 centres reported whether their offspring (aged <= 51 years) had ever had asthma and whether it had coexisted with nasal allergies or not. Mothers and fathers also provided information on their parents' (grandparents) and their own asthma, education and smoking history. Multilevel mediation models within a multicentre three-generation framework were fitted separately within the maternal (4666 offspring) and paternal (4192 offspring) lines. Results: Fathers' smoking before they were 15 [relative risk ratio (RRR) = 1.43, 95% confidence interval (CI): 1.01-2.01] and mothers' smoking during pregnancy (RRR = 1.27, 95% CI: 1.01-1.59) were associated with asthma without nasal allergies in their offspring. Grandmothers' smoking during pregnancy was associated with asthma in their daughters [odds ratio (OR) = 1.55, 95% CI: 1.17-2.06] and with asthma with nasal allergies in their grandchildren within the maternal line (RRR = 1.25, 95% CI: 1.02-1.55). Conclusions: Fathers' smoking during early adolescence and grandmothers' and mothers' smoking during pregnancy may independently increase asthma risk in offspring. Thus, risk factors for asthma should be sought in both parents and before conception. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
653 | a Asthma | |
653 | a mothers' smoking during pregnancy | |
653 | a grandmothers' smoking during pregnancy | |
653 | a fathers' | |
653 | a respiratory-health-survey | |
653 | a maternal nicotine exposure | |
653 | a obstructive | |
653 | a lung-disease | |
653 | a childhood asthma | |
653 | a transgenerational responses | |
653 | a follow-up | |
653 | a pregnancy | |
653 | a cohort | |
653 | a inheritance | |
653 | a expression | |
653 | a asthma | |
700 | 1 | a Calciano, L.u Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy4 aut |
700 | 1 | a Johannessen, A.u Univ Bergen, Dept Global Publ Hlth & Primary Care, Ctr Int Hlth, Bergen, Norway4 aut |
700 | 1 | a Portas, L.u Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy4 aut |
700 | 1 | a Benediktsdottir, B.u Univ Iceland, Fac Med, Reykjavik, Iceland4 aut |
700 | 1 | a Jogi, Rainu Uppsala universitet,Lung- allergi- och sömnforskning,Tartu Univ Hosp, Lung Clin, Tartu, Estonia4 aut0 (Swepub:uu)raijo735 |
700 | 1 | a Bråbäck, Lennartu Umeå universitet,Yrkes- och miljömedicin,Umea Univ, Dept Publ Hlth & Clin Med, Div Occupat & Environm Med, Umea, Sweden4 aut0 (Swepub:umu)lebr0005 |
700 | 1 | a Carsin, A. E.u Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain;UPF, Barcelona, Spain;CIBER Epidemiol & Salud PUbl CIBERESP, Barcelona, Spain4 aut |
700 | 1 | a Dharmage, S. C.u Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy;Univ Melbourne, Sch Populat & Global Hlth, Melbourne, Vic, Australia,Univ Bergen, Dept Global Publ Hlth & Primary Care, Ctr Int Hlth, Bergen, Norway;Haukeland Hosp, Dept Occupat Med, Bergen, Norway4 aut |
700 | 1 | a Dratva, J.u ZHAW Sch Hlth Profess, Inst Hlth Sci, Winterthur, Switzerland;Basel Univ, Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland4 aut |
700 | 1 | a Forsberg, Bertilu Umeå universitet,Yrkes- och miljömedicin,Umea Univ, Dept Publ Hlth & Clin Med, Div Occupat & Environm Med, Umea, Sweden4 aut0 (Swepub:umu)befo0001 |
700 | 1 | a Real, F. G.u Univ Bergen, Dept Clin Sci, Bergen, Norway4 aut |
700 | 1 | a Heinrich, J.u Ludwig Maximilians Univ Munchen, Univ Hosp Munich, Inner City Clin, Inst & Outpatient Clin Occupat,Social & Environm, Munich, Germany4 aut |
700 | 1 | a Holloway, J. W.u Univ Southampton, Fac Med, Human Dev & Hlth, Southampton, Hants, England,Univ Antwerp, Dept Epidemiol & Social Med, Antwerp, Belgium;Univ Antwerp, StatUA Stat Ctr, Antwerp, Belgium4 aut |
700 | 1 | a Holm, Mathias,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Univ Gothenburg, Sahlgrenska Acad, Dept Occupat & Environm Med, Gothenburg, Sweden4 aut0 (Swepub:gu)xhomat |
700 | 1 | a Janson, Christeru Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)chrisjn |
700 | 1 | a Jogi, R.4 aut |
700 | 1 | a Leynaert, B.u INSERM, Pathophysiol & Epidemiol Resp Dis, UMR 1152, Paris, France4 aut |
700 | 1 | a Malinovschi, Andrei,d 1978-u Uppsala universitet,Klinisk fysiologi4 aut0 (Swepub:uu)anmal535 |
700 | 1 | a Marcon, A.u Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy4 aut |
700 | 1 | a Rovira, J. M.u CHUA, Hlth Serv Castilla La Mancha SESCAM, Pneumol Serv, Albacete, Spain;Univ Castilla La Mancha, Sch Med, Albacete, Spain4 aut |
700 | 1 | a Raherison, C.u Bordeaux Univ, INSERM, U1219, Bordeaux, France4 aut |
700 | 1 | a Sanchez-Ramos, J.u Univ Huelva, Dept Nursing, Huelva, Spain4 aut |
700 | 1 | a Schlunssen, V.u Aarhus Univ, Dept Publ Hlth, Aarhus, Denmark;Natl Res Ctr Working Environm, Copenhagen, Denmark4 aut |
700 | 1 | a Bono, R.u Univ Turin, Dept Publ Hlth & Pediat, Turin, Italy4 aut |
700 | 1 | a Corsico, A. G.u Univ Pavia, IRCCS San Matteo Hosp Fdn, Div Resp Dis, Pavia, Italy4 aut |
700 | 1 | a Demoly, P.u Univ Montpellier, Hop Arnaud Villeneuve, Dept Pneumol & Addictol, Montpellier, France;Sorbonne Univ, INSERM, IPLESP, Paris, France4 aut |
700 | 1 | a Arenas, S.u Galdakao Usansolo Hosp, Pulmonol Dept, Biscay, Spain4 aut |
700 | 1 | a Nowak, D.u Ludwig Maximilians Univ Munchen, Univ Hosp Munich, Inner City Clin, Inst & Outpatient Clin Occupat,Social & Environm, Munich, Germany;Comprehens Pneumol Ctr Munich, German Ctr Lung Res, Munich, Germany4 aut |
700 | 1 | a Pin, I.u CHU Grenoble Alpes, Pediat, Grenoble, France;Inst Adv Biosci, INSERM 1209, Grenoble, France;Univ Grenoble Alpes, Grenoble, France4 aut |
700 | 1 | a Weyler, J.4 aut |
700 | 1 | a Jarvis, D.u Imperial Coll, Natl Heart & Lung Inst, Populat Hlth & Occupat Dis, London, England;Imperial Coll, MRC PHE Ctr Environm & Hlth, London, England4 aut |
700 | 1 | a Svanes, C.4 aut |
710 | 2 | a Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italyb Univ Bergen, Dept Global Publ Hlth & Primary Care, Ctr Int Hlth, Bergen, Norway4 org |
773 | 0 | t International Journal of Epidemiologyd : Oxford University Press (OUP)g 47:4, s. 1106-1117q 47:4<1106-1117x 0300-5771x 1464-3685 |
856 | 4 | u https://academic.oup.com/ije/article-pdf/47/4/1106/25687458/dyy031.pdf |
856 | 4 | u https://doi.org/10.1093/ije/dyy031y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1191092/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1265178/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://gup.ub.gu.se/publication/271748 |
856 | 4 8 | u https://doi.org/10.1093/ije/dyy031 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-145740 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-365986 |
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