Search: onr:"swepub:oai:gup.ub.gu.se/273390" > The association of ...
Fältnamn | Indikatorer | Metadata |
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000 | 06002naa a2201033 4500 | |
001 | oai:gup.ub.gu.se/273390 | |
003 | SwePub | |
008 | 240528s2012 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:4382f9cf-43de-4e7b-b564-25e29382efb8 | |
009 | oai:prod.swepub.kib.ki.se:124340793 | |
009 | oai:DiVA.org:umu-55296 | |
024 | 7 | a https://gup.ub.gu.se/publication/2733902 URI |
024 | 7 | a https://doi.org/10.1002/ijc.262442 DOI |
024 | 7 | a https://lup.lub.lu.se/record/25873992 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1243407932 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-552962 URI |
040 | a (SwePub)gud (SwePub)lud (SwePub)kid (SwePub)umu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Grote, Verena A.4 aut |
245 | 1 0 | a The association of circulating adiponectin levels with pancreatic cancer risk: A study within the prospective EPIC cohort |
264 | c 2011-09-17 | |
264 | 1 | b Wiley,c 2012 |
520 | a Excess body weight and type 2 diabetes mellitus, risk factors of pancreatic cancer, are characterized by decreased levels of adiponectin. In addition to anti-inflammatory and anti-proliferative actions, adiponectin has an important role in regulating glucose metabolism, i.e., decreasing circulating blood glucose levels. Prospectively, hyperglycemia has been associated with risk of pancreatic cancer. The aim of this study was to investigate the association of pre-diagnostic adiponectin levels with pancreatic cancer risk. We conducted a case-control study nested within European Prospective Investigation into Cancer and Nutrition. Blood samples of 452 pancreatic cancer cases and 452 individually matched controls were analyzed by immunoassays. Multivariate conditional logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI). Overall, adiponectin showed no association with pancreas cancer risk; however, among never smokers, higher circulating levels of adiponectin were associated with a reduction in pancreatic cancer risk (OR = 0.44 [95% CI 0.23-0.82] for highest vs. lowest quartile), whereas among current smokers there was no significant association (OR = 1.59 [95% CI 0.67-3.76] for highest vs. lowest quartile; p-trend = 0.530; p-interaction = 0.309). In our study, lower adiponectin concentrations may be associated with the development of pancreatic cancer among never smokers, whereas the only other prospective study being conducted so far showed a decrease in risk among male smokers. Therefore, further studies are needed to clarify the role of adiponectin in pancreatic cancer development. © 2011 UICC. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a adiponectin | |
653 | a cohort study | |
653 | a EPIC | |
653 | a pancreatic cancer | |
653 | a adiponectin | |
700 | 1 | a Rohrmann, Sabine4 aut |
700 | 1 | a Dossus, Laure4 aut |
700 | 1 | a Nieters, Alexandra4 aut |
700 | 1 | a Halkjær, Jytte4 aut |
700 | 1 | a Tjønneland, Anne4 aut |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Stegger, Jakob4 aut |
700 | 1 | a Chabbert-Buffet, Nathalie4 aut |
700 | 1 | a Boutron-Ruault, Marie Christine4 aut |
700 | 1 | a Clavel-Chapelon, Françoise4 aut |
700 | 1 | a Teucher, Birgit4 aut |
700 | 1 | a Becker, Susen4 aut |
700 | 1 | a Montonen, Jukka4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Trichopoulou, Antonia4 aut |
700 | 1 | a Lagiou, Pagona4 aut |
700 | 1 | a Trichopoulos, Dimitrios4 aut |
700 | 1 | a Palli, Domenico4 aut |
700 | 1 | a Sieri, Sabina4 aut |
700 | 1 | a Tumino, Rosario4 aut |
700 | 1 | a Vineis, Paolo4 aut |
700 | 1 | a Mattiello, Amalia4 aut |
700 | 1 | a Argüelles, Marcial4 aut |
700 | 1 | a Duell, Eric J.4 aut |
700 | 1 | a Molina-Montes, Esther4 aut |
700 | 1 | a Larrañaga, Nerea4 aut |
700 | 1 | a Chirlaque, María Dolores4 aut |
700 | 1 | a Gurrea, Aurelio Barricarte4 aut |
700 | 1 | a Jeurnink, Suzanne M.4 aut |
700 | 1 | a Peeters, Petra H.M.4 aut |
700 | 1 | a Ye, Weiminu Karolinska Institutet4 aut |
700 | 1 | a Sund, Malinu Umeå universitet,Kirurgi,Institutionen för folkhälsa och klinisk medicin4 aut0 (Swepub:umu)masu0021 |
700 | 1 | a Lindkvist, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xlibjo |
700 | 1 | a Johansen, Dortheu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kirm-djo |
700 | 1 | a Khaw, Kay Tee4 aut |
700 | 1 | a Wareham, Nick4 aut |
700 | 1 | a Crowe, Francesca L.4 aut |
700 | 1 | a Romieu, Isabelle4 aut |
700 | 1 | a Rinaldi, Sabina4 aut |
700 | 1 | a Jenab, Mazda4 aut |
700 | 1 | a Romaguera, Dora4 aut |
700 | 1 | a Michaud, Dominique S.4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Bas Bueno-De-Mesquita, H.4 aut |
700 | 1 | a Kaaks, Rudolf4 aut |
710 | 2 | a Karolinska Institutetb Kirurgi4 org |
773 | 0 | t International Journal of Cancerd : Wileyg 130, s. 2428-2437q 130<2428-2437x 0020-7136x 1097-0215 |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.26244 |
856 | 4 | u http://dx.doi.org/10.1002/ijc.26244y FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/273390 |
856 | 4 8 | u https://doi.org/10.1002/ijc.26244 |
856 | 4 8 | u https://lup.lub.lu.se/record/2587399 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:124340793 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-55296 |
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