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FältnamnIndikatorerMetadata
00028759naa a2202425 4500
001oai:gup.ub.gu.se/280055
003SwePub
008240528s2019 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-380499
009oai:lup.lub.lu.se:88b31e13-d9a4-49a8-a527-d51bd04337b1
024a https://gup.ub.gu.se/publication/2800552 URI
024a https://doi.org/10.1093/ajcn/nqy2722 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3804992 URI
024a https://lup.lub.lu.se/record/88b31e13-d9a4-49a8-a527-d51bd04337b12 URI
040 a (SwePub)gud (SwePub)uud (SwePub)lu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Karasik, D.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Bar Ilan Univ, Azrieli Fac Med, Safed, Israel,Harvard University,Bar-Ilan University4 aut
2451 0a Disentangling the genetics of lean mass
264 1b Elsevier BV,c 2019
520 a Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives: To determine the impact of different fat mass adjustments on genetic architecture of LM and identify additional LM loci. Methods: We performed genome-wide association analyses for whole-body LM (20 cohorts of European ancestry with n = 38,292) measured using dual-energy X-ray absorptiometry) or bioelectrical impedance analysis, adjusted for sex, age, age(2), and height with or without fat mass adjustments (Model 1 no fat adjustment; Model 2 adjustment for fat mass as a percentage of body mass; Model 3 adjustment for fat mass in kilograms). Results: Seven single-nucleotide polymorphisms (SNPs) in separate loci, including one novel LM locus (TNRC6B), were successfully replicated in an additional 47,227 individuals from 29 cohorts. Based on the strengths of the associations in Model 1 vs Model 3, we divided the LM loci into those with an effect on both lean mass and fat mass in the same direction and refer to those as "sumo wrestler" loci (FTO and MC4R). In contrast, loci with an impact specifically on LMwere termed "body builder" loci (VCAN and ADAMTSL3). Using existing available genome-wide association study databases, LM increasing alleles of SNPs in sumo wrestler loci were associated with an adverse metabolic profile, whereas LM increasing alleles of SNPs in "body builder" loci were associated with metabolic protection. Conclusions: In conclusion, we identified one novel LM locus (TNRC6B). Our results suggest that a genetically determined increase in lean mass might exert either harmful or protective effects on metabolic traits, depending on its relation to fat mass.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
653 a body composition
653 a skeletal muscle
653 a body fat
653 a meta-analysis of genome-wide association studies
653 a genome-wide association
653 a skeletal-muscle mass
653 a ld score regression
653 a body-mass
653 a susceptibility loci
653 a metaanalysis
653 a insights
653 a density
653 a Nutrition & Dietetics
653 a body composition
700a Zillikens, M. C.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut
700a Hsu, Y. H.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Harvard Med Sch, Dept Med, Boston, MA 02115 USA;Harvard Sch Publ Hlth, Mol & Integrat Physiol Sci Program, Boston, MA USA4 aut
700a Aghdassi, A.u Ernst Moritz Arndt Univ Greifswald, Dept Med A, Greifswald, Germany,Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA,Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA,Erasmus MC, Dept Clin Genet, Rotterdam, Netherlands;Ctr Med Syst Biol & Netherlands Consortium H, Leiden, Netherlands,Univ Calif Davis, Dept Med, Sacramento, CA 95817 USA,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;Vet Adm Med Ctr, Geriatr Res & Educ Clin Ctr, Baltimore, MD 21218 USA,Vrije Univ Amsterdam Med Ctr, Dept Epidemiol & Biostat, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, EMGO Inst, Amsterdam, Netherlands4 aut
700a Åkesson, Kristinau Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)orto-kak
700a Amin, N.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700a Barroso, I.u Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England;NIHR Cambridge Biomed Res Ctr, Cambridge, England;Univ Cambridge, Metab Res Labs, Inst Metab Sci, Addenbrookes Hosp, Cambridge, England,Washington Univ, Dept Genet, Div Stat Gen, Sch Med, St Louis, MO 63110 USA;Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA4 aut
700a Bennett, D. A.4 aut
700a Bertram, L.u Univ Lubeck, Lubeck Interdisciplinary Platform Genome Analyt, Lubeck, Germany,Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark4 aut
700a Bochud, M.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland4 aut
700a Borecki, I. B.4 aut
700a Broer, L.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700a Buchman, A. S.u Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA,Univ Tennessee, Ctr Hlth Sci, Dept Prevent Med, Memphis, TN 38163 USA,Ernst Moritz Arndt Univ Greifswald, Inst Community Med, Greifswald, Germany,Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut
700a Byberg, Liisau Uppsala universitet,Ortopedi4 aut0 (Swepub:uu)liisbybe
700a Campbell, H.u Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Teviot Pl, Edinburgh, Midlothian, Scotland4 aut
700a Campos-Obando, N.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut
700a Cauley, J. A.u Natl Inst Hlth & Welfare, Helsinki, Finland4 aut
700a Cawthon, P. M.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Columbia Univ, Med Ctr, Ctr Translat & Computat Neuroimmunol Neurol, New York, NY USA,Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA,Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Inst Mol Med, Helsinki, Finland;Diabet & Obes Res Program, Helsinki, Finland;Univ Tartu, Estonian Genome Ctr, Tartu, Estonia4 aut
700a Chambers, J. C.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England;Imperial Coll Healthcare NHS Trust, London, England;Royal Brompton & Harefield NHS Fdn Trust, NIHR Cardiovasc Biomed Res Unit, London, England;Imperial Coll London, London, England4 aut
700a Chen, Z.u Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ USA4 aut
700a Cho, N. H.u Ajou Univ, Sch Med, Dept Prevent Med, Suwon, South Korea4 aut
700a Choi, H. J.u Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea;Seoul Natl Univ, Coll Med, Neurosci Res Inst, Dept Anat & Cell Biol, Seoul, South Korea;Seoul Natl Univ, Wide River Inst Immunol, Hongcheon, South Korea4 aut
700a Chou, W. C.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Broad Inst, Cambridge, MA USA,Univ Alabama Birmingham, Dept Epidemiol, Birmingham, AL USA4 aut
700a Cummings, S. R.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland;Univ Helsinki, Hjelt Inst, Helsinki, Finland4 aut
700a de Groot, Lcpgm4 aut
700a Lind, Larsu Uppsala universitet,Klinisk epidemiologi,Univ Western Australia, Sch Med & Pharmacol, Perth, WA, Australia;Sir Charles Gairdner Hosp, Dept Endocrinol & Diabet, Perth, WA, Australia4 aut0 (Swepub:uu)larslind
700a Demuth, I.u Berlin Inst Hlth, Berlin, Germany;Wageningen Univ, Div Human Nutr, AFSG, Wageningen, Netherlands4 aut
700a Diatchenko, L.u Univ North Carolina Chapel Hill, Sch Dent, Reg Ctr Neurosensory Disorders, Chapel Hill, NC USA;McGill Univ, Alan Edwards Ctr Res Pain, Montreal, PQ, Canada4 aut
700a Econs, M. J.u Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA4 aut
700a Eiriksdottir, G.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland4 aut
700a Enneman, A. W.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut
700a Eriksson, Joelu Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xerjoe
700a Eriksson, J. G.u Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Dept Gen Practice & Primary Hlth Care, Helsinki, Finland;Helsinki Univ Cent Hosp, Unit Gen Practice, Helsinki, Finland;Folkhalsan Res Ctr, Helsinki, Finland4 aut
700a Estrada, K.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Biogen Inc, Translat Biol, 14 Cambridge Ctr, Cambridge, MA 02142 USA,Duke Univ, Sch Med, Dept Med, Duke Mol Physiol Inst, Durham, NC USA;Duke Univ, Sch Med, Dept Med, Div Cardiol, Durham, NC USA4 aut
700a Evans, D. S.u Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA,Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut
700a Feitosa, M. F.u Washington Univ, Dept Genet, Div Stat Gen, Sch Med, St Louis, MO 63110 USA,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA4 aut
700a Fu, M.4 aut
700a Gieger, C.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany4 aut
700a Grallert, H.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Helmholtz Zentrum Munchen, CCG Type 2 Diabet, Neuherberg, Germany;German Ctr Diabet Res, Neuherberg, Germany4 aut
700a Gudnason, V.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland;Univ Iceland, Fac Med, Reykjavik, Iceland4 aut
700a Lenore, L. J.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands,Univ Helsinki, Helsinki Collegium Adv Studies, Helsinki, Finland4 aut
700a Hayward, C.u Univ Edinburgh, MRC Human Genet Unit, IGMM, Edinburgh, Midlothian, Scotland4 aut
700a Hofman, A.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut
700a Homuth, G.u Ernst Moritz Arndt Univ Greifswald, Interfac Inst Genet & Funct Gen, Greifswald, Germany4 aut
700a Michaëlsson, Karl,d 1959-u Uppsala universitet,Ortopedi,Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden,Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut0 (Swepub:uu)karlmich
700a Husted, L. B.4 aut
700a Illig, T.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Hannover Med Sch, Dept Human Genet, Hannover, Germany4 aut
700a Ingelsson, E.u Stanford Univ, Sch Med, Dept Med, Div Cardiovasc Med, Stanford, CA USA4 aut
700a Ittermann, T.u Ernst Moritz Arndt Univ Greifswald, Inst Community Med, Greifswald, Germany4 aut
700a Jansson, John-Olov,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology,Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Physiol, Gothenburg, Sweden4 aut0 (Swepub:gu)xjanjo
700a Johnson, T.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland;Univ Lausanne, Dept Med Genet, Lausanne, Switzerland;Swiss Inst Bioinformat, Lausanne, Switzerland,Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA4 aut
700a Biffar, R.u Ernst Moritz Arndt Univ Greifswald, Dept Prosthet Dent Gerodontol & Biomat, Ctr Oral Hlth, Greifswald, Germany4 aut
700a Jordan, J. M.u Univ North Carolina Chapel Hill, Thurston Arthrit Res Ctr, Chapel Hill, NC USA4 aut
700a Jula, A.4 aut
700a Karlsson, Magnusu Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)orto-mka
700a Khaw, K. T.u Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England,Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut
700a Kilpelainen, T. O.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England;Univ Copenhagen, Fac Hlth & Med Sci, Sect Metabol Genet, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark;Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA4 aut
700a Klopp, N.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Hannover Med Sch, Hannover Unified Biobank, Hannover, Germany4 aut
700a Kloth, J. S. L.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands4 aut
700a Koller, D. L.u Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA4 aut
700a Kooner, J. S.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll Healthcare NHS Trust, London, England;Imperial Coll London, Hammersmith Hosp, Natl Heart & Lung Inst Cardiovasc Sci, Fac Med, Hammersmith Campus, London, England4 aut
700a Kraus, W. E.u Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland4 aut
700a Kritchevsky, S.u Wake Forest Sch Med, Sticht Ctr Hlth Aging & Alzheimers Prevent, Winston Salem, NC USA4 aut
700a Kutalik, Z.u Lausanne Univ Hosp, Univ Inst Social & Prevent Med, Lausanne, Switzerland;Helmholtz Zentrum Munchen, CCG Nutrigen & Type 2 Diabet, Neuherberg, Germany;Swiss Inst Bioinformat, Lausanne, Switzerland4 aut
700a Kuulasmaa, T.4 aut
700a Kuusisto, J.u Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut
700a Laakso, M.u Univ Eastern Finland, Dept Med, Kuopio, Finland;Kuopio Univ Hosp, Kuopio, Finland4 aut
700a Lahti, J.4 aut
700a Lang, T.u UC San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA USA;UC San Francisco, Sch Dent, San Francisco, CA USA4 aut
700a Langdahl, B. L.u Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark4 aut
700a Lerch, M. M.u Ernst Moritz Arndt Univ Greifswald, Dept Med A, Greifswald, Germany4 aut
700a Lewis, J. R.u Univ Western Australia, Sch Med & Pharmacol, Perth, WA, Australia;Univ Sydney, Sydney Med Sch, Sch Publ Hlth, Childrens Hosp Westmead,Ctr Kidney Res, Sydney, NSW, Australia4 aut
700a Lill, C.u Univ Lubeck, Inst Neurogenet, Lubeck, Germany4 aut
700a Lind, L.4 aut
700a Lindgren, C.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England4 aut
700a Liu, Y. M.u Wake Forest Sch Med, Dept Epidemiol & Prevent, Winston Salem, NC USA4 aut
700a Livshits, G.u Tel Aviv Univ, Dept Anat & Anthropol, Sackler Fac Med, Tel Aviv, Israel;Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut
700a Ljunggren, Östenu Uppsala universitet,Endokrinologi och mineralmetabolism4 aut0 (Swepub:uu)osteljun
700a Loos, R. J. F.u Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA;Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA;Icahn Sch Med Mt Sinai, Inst Child Hlth & Dev, New York, NY 10029 USA;Icahn Sch Med Mt Sinai, Genet Obes & Related Traits Program, New York, NY 10029 USA,Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700a Lorentzon, Mattias,d 1970u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med, Gothenburg, Sweden4 aut0 (Swepub:gu)xlomat
700a Luan, J.u Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, New York, NY USA4 aut
700a Luben, R. N.u Univ Copenhagen, Fac Hlth & Med Sci, Sect Metabol Genet, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark4 aut
700a Malkin, I.u Tel Aviv Univ, Dept Anat & Anthropol, Sackler Fac Med, Tel Aviv, Israel4 aut
700a McGuigan, F. E.u Lund Univ, Dept Clin Sci Malmo, Malmo, Sweden4 aut
700a Medina-Gomez, C.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700a Meitinger, T.u Tech Univ Munich, Inst Human Genet, MRI, Munich, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Human Genet, Neuherberg, Germany4 aut
700a Melhus, Håkanu Uppsala universitet,Klinisk farmakogenomik och osteoporos4 aut0 (Swepub:uu)hakamelh
700a Mellström, Dan,d 1945u Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden,Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Ctr Med Syst Biol & Netherlands Consortium H, Leiden, Netherlands,Vrije Univ Amsterdam Med Ctr, Dept Epidemiol & Biostat, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, EMGO Inst, Amsterdam, Netherlands4 aut0 (Swepub:gu)xmelda
700a Michaelsson, K.4 aut
700a Mitchell, B. D.u Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;Vet Adm Med Ctr, Geriatr Res & Educ Clin Ctr, Baltimore, MD 21218 USA4 aut
700a Morris, A. P.u Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England;Univ Liverpool, Inst Translat Med, Liverpool, Merseyside, England,Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland;Univ Helsinki, Dept Med Genet, Helsinki, Finland;Univ Cent Hosp, Helsinki, Finland,Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Res Unit Mol Epidemiol, Neuherberg, Germany;Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany4 aut
700a Mosekilde, L.u Aarhus Univ Hosp, Endocrinol & Internal Med, Aarhus, Denmark,Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA;GlaxoSmithKline, Genet, King Of Prussia, PA USA4 aut
700a Nethander, Maria,d 1980u Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xnetma
700a Newman, A. B.u Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA4 aut
700a O'Connell, J. R.u Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Program Personalized & Genom Med, Baltimore, MD 21201 USA;Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Dept Med, Baltimore, MD 21201 USA4 aut
700a Oostra, B. A.4 aut
700a Orwoll, E. S.u Oregon Hlth & Sci Univ, Portland, OR USA4 aut
700a Palotie, A.4 aut
700a Peacock, M.4 aut
700a Perola, M.4 aut
700a Peters, A.4 aut
700a Prince, R. L.4 aut
700a Psaty, B. M.u Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA;Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA4 aut
700a Raikkonen, K.u Univ Helsinki, Dept Psychol & Logoped, Helsinki, Finland4 aut
700a Ralston, S. H.u Harvard Med Sch, Boston, MA 02115 USA;Western Gen Hosp, MRC Inst Genet & Mol Med, Mol Med Ctr, Edinburgh, Midlothian, Scotland4 aut
700a Ripatti, S.4 aut
700a Rivadeneira, F.4 aut
700a Robbins, J. A.4 aut
700a Rotter, J. I.u Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles Biomed Res Inst, Torrance, CA 90509 USA;Harbor UCLA Med Ctr, Dept Pediat, Torrance, CA 90509 USA4 aut
700a Rudan, I.u Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA4 aut
700a Salomaa, V.u Natl Inst Hlth & Welfare, Helsinki, Finland4 aut
700a Satterfield, S.4 aut
700a Schipf, S.4 aut
700a Shin, C. S.u Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea4 aut
700a Smith, A. V.u Iceland Heart Assoc Holtasmari, Kopavogur, Iceland;Univ Iceland, Fac Med, Reykjavik, Iceland4 aut
700a Smith, S. B.u Duke Univ, Dept Anesthesiol, Ctr Translat Pain Med, Durham, NC USA4 aut
700a Soranzo, N.u Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England4 aut
700a Spector, T. D.u Kings Coll London, Dept Twin Res & Genet Epidemiol, St Thomas Campus, London, England4 aut
700a Stancakova, A.4 aut
700a Stefansson, K.u Univ Iceland, Fac Med, Reykjavik, Iceland;deCODE Genet, Reykjavik, Iceland4 aut
700a Steinhagen-Thiessen, E.u Harvard Sch Publ Hlth, Mol & Integrat Physiol Sci Program, Boston, MA USA4 aut
700a Stolk, L.4 aut
700a Streeten, E. A.4 aut
700a Styrkarsdottir, U.u deCODE Genet, Reykjavik, Iceland4 aut
700a Swart, K. M. A.4 aut
700a Thompson, P.u Univ Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Tucson, AZ USA;SUNY Stony Brook, Dept Pathol, Stony Brook, NY 11794 USA4 aut
700a Thomson, C. A.4 aut
700a Thorleifsson, G.u deCODE Genet, Reykjavik, Iceland4 aut
700a Thorsteinsdottir, U.u Univ Iceland, Fac Med, Reykjavik, Iceland;deCODE Genet, Reykjavik, Iceland4 aut
700a Tikkanen, E.u Natl Inst Hlth & Welfare, Helsinki, Finland;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland4 aut
700a Tranah, G. J.4 aut
700a Uitterlinden, A. G.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands;Netherlands Genom Initiat, Leiden, Netherlands;Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700a van Duijn, C. M.4 aut
700a van Schoor, N. M.4 aut
700a Vandenput, L.u Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut
700a Vollenweider, P.u Lausanne Univ Hosp, Dept Med Internal Med, Lausanne, Switzerland;Fac Biol & Med, Lausanne, Switzerland4 aut
700a Volzke, H.u Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut
700a Wactawski-Wende, J.u Univ Buffalo SUNY, Dept Epidemiol & Environm Hlth, Buffalo, NY USA4 aut
700a Walker, M.u Newcastle Univ, Med Sch, Inst Cellular Med Diabetes, Framlington Pl, Newcastle Upon Tyne, Tyne & Wear, England4 aut
700a Wareham, N. J.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England4 aut
700a Waterworth, D.u GlaxoSmithKline, Genet, King Of Prussia, PA USA4 aut
700a Weedon, M. N.u Univ Exeter, Med Sch, Royal Devon & Exeter Hosp, Genet Complex Traits, Exeter, Devon, England4 aut
700a Wichmann, H. E.u Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, Neuherberg, Germany;Ludwig Maximilians Univ Munchen, Inst Med Informat Biometry & Epidemiol, Neuherberg, Germany;Tech Univ, Inst Med Stat & Epidemiol, Munich, Germany4 aut
700a Widen, E.4 aut
700a Williams, F. M. K.4 aut
700a Wilson, J. F.u Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Teviot Pl, Edinburgh, Midlothian, Scotland4 aut
700a Wright, N. C.4 aut
700a Yerges-Armstrong, L. M.4 aut
700a Yu, L.u Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA4 aut
700a Zhang, W. H.u Ealing Hosp NHS Trust, Cardiol, London, England;Imperial Coll Healthcare NHS Trust, London, England4 aut
700a Zhao, J. H.u Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England4 aut
700a Zhou, Y. H.u Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut
700a Nielson, C. M.u Oregon Hlth & Sci Univ, Portland, OR USA4 aut
700a Harris, T. B.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, Bethesda, MD 20892 USA4 aut
700a Demissie, S.4 aut
700a Kiel, D. P.u Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Harvard Med Sch, Dept Med, Boston, MA 02115 USA4 aut
700a Ohlsson, Claes,d 1965u University of Gothenburg,Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Internal Med & Clin Nutr, Gothenburg, Sweden4 aut0 (Swepub:gu)xohlcl
710a Hebrew Senior Life Inst Aging Res, Boston, MA USA;Harvard Med Sch, Boston, MA 02115 USA;Bar Ilan Univ, Azrieli Fac Med, Safed, Israelb Harvard University4 org
773t American Journal of Clinical Nutritiond : Elsevier BVg 109:2, s. 276-287q 109:2<276-287x 0002-9165x 1938-3207
856u https://academic.oup.com/ajcn/article-pdf/109/2/276/28887492/nqy272.pdf
856u http://dx.doi.org/10.1093/ajcn/nqy272y FULLTEXT
8564 8u https://gup.ub.gu.se/publication/280055
8564 8u https://doi.org/10.1093/ajcn/nqy272
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-380499
8564 8u https://lup.lub.lu.se/record/88b31e13-d9a4-49a8-a527-d51bd04337b1

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