onr:"swepub:oai:gup.ub.gu.se/280413"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03096naa a2200553 4500 | |
| 001 | oai:gup.ub.gu.se/280413 | |
| 003 | SwePub | |
| 008 | 240528s2002 | |||||||||||000 ||hun| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2804132 URI |
| 040 | a (SwePub)gu | |
| 041 | a hun | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Kovács, Anikó,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin , Avdelningen för patologi,Institute of Laboratory Medicine, Dept of Pathology4 aut0 (Swepub:gu)xkovan |
| 245 | 1 0 | a [Immunohistochemical study of P-cadherin in breast cancer]. :b P-cadherin immunhisztokémiai vizsgálata emlórákokban. |
| 264 | 1 | c 2002 |
| 520 | a Cell adhesion molecules play a significant role in the cellular connection of normal cells. The cadherins are believed to act as tumour suppressors, and their altered expression and function have been associated with tumour development.The authors examined the expression of a Ca++ dependent intercellular adhesion molecule, P-cadherin using an immunohistochemical method in 69 surgically resected breast carcinomas.P-cadherin was detected in 30 cases (43.5%, cytoplasmic and/or membrane staining). The expression of P-cadherin was independent of tumour size and lymph node status, but correlated with a high tumour grade (grade III). In contrast, expression of E-cadherin correlated with lower tumour grade (grade I-II). P-cadherin expression was not detected in invasive lobular carcinomas.In general, P-cadherin was expressed at a lower frequency compared to E-cadherin, alpha-, and beta-catenin. These results suggest that an inverse relationship may exist between E- and P-cadherin in relation to grade, and that the expression of P-cadherin may be a marker of aggressiveness. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng |
| 653 | a Breast Neoplasms | |
| 653 | a chemistry | |
| 653 | a pathology | |
| 653 | a Cadherins | |
| 653 | a analysis | |
| 653 | a Carcinoma | |
| 653 | a Ductal | |
| 653 | a Breast | |
| 653 | a chemistry | |
| 653 | a pathology | |
| 653 | a Female | |
| 653 | a Gene Expression Regulation | |
| 653 | a Neoplastic | |
| 653 | a Humans | |
| 653 | a Immunohistochemistry | |
| 653 | a Receptors | |
| 653 | a Estrogen | |
| 653 | a analysis | |
| 653 | a Receptors | |
| 653 | a Progesterone | |
| 653 | a analysis | |
| 700 | 1 | a Walker, Rosemary A4 aut |
| 700 | 1 | a Nagy, András4 aut |
| 700 | 1 | a Gomba, Szabolcs4 aut |
| 700 | 1 | a Jones, Louise4 aut |
| 700 | 1 | a Dearing, Sheila4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för laboratoriemedicin , Avdelningen för patologi4 org |
| 773 | 0 | t Orvosi hetilapg 143:8, s. 405-9q 143:8<405-9x 0030-6002 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/280413 |
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