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Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study

Burn, E. (author)
You, S. C. (author)
Sena, A. G. (author)
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Kostka, K. (author)
Abedtash, H. (author)
Abrahao, M. T. F. (author)
Alberga, A. (author)
Alghoul, H. (author)
Alser, O. (author)
Alshammari, T. M. (author)
Aragon, M. (author)
Areia, C. (author)
Banda, J. M. (author)
Cho, J. (author)
Culhane, A. C. (author)
Davydov, A. (author)
DeFalco, F. J. (author)
Duarte-Salles, T. (author)
DuVall, S. (author)
Falconer, T. (author)
Fernandez-Bertolin, S. (author)
Gao, W. H. (author)
Golozar, A. (author)
Hardin, J. (author)
Hripcsak, G. (author)
Huser, V. (author)
Jeon, H. (author)
Jing, Y. H. (author)
Jung, C. Y. (author)
Kaas-Hansen, B. S. (author)
Kaduk, D. (author)
Kent, S. (author)
Kim, Y. (author)
Kolovos, S. (author)
Lane, J. C. E. (author)
Lee, H. (author)
Lynch, K. E. (author)
Makadia, R. (author)
Matheny, M. E. (author)
Mehta, P. P. (author)
Morales, D. R. (author)
Natarajan, K. (author)
Nyberg, Fredrik, 1961 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
Ostropolets, A. (author)
Park, R. W. (author)
Park, J. (author)
Posada, J. D. (author)
Prats-Uribe, A. (author)
Rao, G. (author)
Reich, C. (author)
Rho, Y. (author)
Rijnbeek, P. (author)
Schilling, L. M. (author)
Schuemie, M. (author)
Shah, N. H. (author)
Shoaibi, A. (author)
Song, S. (author)
Spotnitz, M. (author)
Suchard, M. A. (author)
Swerdel, J. N. (author)
Vizcaya, D. (author)
Volpe, S. (author)
Wen, H. N. (author)
Williams, A. E. (author)
Yimer, B. B. (author)
Zhang, L. (author)
Zhuk, O. (author)
Prieto-Alhambra, D. (author)
Ryan, P. (author)
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 (creator_code:org_t)
2020-10-06
2020
English.
In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 11:1
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19. Detailed knowledge of the characteristics of COVID-19 patients helps with public health planning. Here, the authors use routinely-collected data from seven databases in three countries to describe the characteristics of >30,000 patients admitted with COVID-19 and compare them with those admitted for influenza in previous years.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

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