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Sökning: onr:"swepub:oai:gup.ub.gu.se/302573" > Variations in knowl...

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FältnamnIndikatorerMetadata
00004831naa a2200841 4500
001oai:gup.ub.gu.se/302573
003SwePub
008240528s2021 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/3025732 URI
024a https://doi.org/10.1136/heartjnl-2019-3165152 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a O'Donnell, M.4 aut
2451 0a Variations in knowledge, awareness and treatment of hypertension and stroke risk by country income level
264 c 2020-12-14
264 1b BMJ,c 2021
520 a Objective Hypertension is the most important modifiable risk factor for stroke globally. We hypothesised that country-income level variations in knowledge, detection and treatment of hypertension may contribute to variations in the association of blood pressure with stroke. Methods We undertook a standardised case-control study in 32 countries (INTERSTROKE). Cases were patients with acute first stroke (n=13 462) who were matched by age, sex and site to controls (n=13 483). We evaluated the associations of knowledge, awareness and treatment of hypertension with risk of stroke and its subtypes and whether this varied by gross national income (GNI) of country. We estimated OR and population attributable risk (PAR) associated with treated and untreated hypertension. Results Hypertension was associated with a graded increase in OR by reducing GNI, ranging from OR 1.92 (99% CI 1.48 to 2.49) to OR 3.27 (2.72 to 3.93) for highest to lowest country-level GNI (p-heterogeneity<0.0001). Untreated hypertension was associated with a higher OR for stroke (OR 5.25; 4.53 to 6.10) than treated hypertension (OR 2.60; 2.32 to 2.91) and younger age of first stroke (61.4 vs 65.4 years; p<0.01). Untreated hypertension was associated with a greater risk of intracerebral haemorrhage (OR 6.95; 5.61 to 8.60) than ischaemic stroke (OR 4.76; 3.99 to 5.68). The PAR associated with untreated hypertension was higher in lower-income regions, PAR 36.3%, 26.3%, 19.8% to 10.4% by increasing GNI of countries. Lifetime non-measurement of blood pressure was associated with stroke (OR 1.80; 1.32 to 2.46). Conclusions Deficits in knowledge, detection and treatment of hypertension contribute to higher risk of stroke, younger age of onset and larger proportion of intracerebral haemorrhage in lower-income countries.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a stroke
653 a hypertension
653 a epidemiology
653 a Cardiovascular System & Cardiology
700a Hankey, G. J.4 aut
700a Rangarajan, S.4 aut
700a Chin, S. L.4 aut
700a Rao-Melacini, P.4 aut
700a Ferguson, J.4 aut
700a Xavier, D.4 aut
700a Liu, L. S.4 aut
700a Zhang, H. Y.4 aut
700a Pais, P.4 aut
700a Lopez-Jaramillo, P.4 aut
700a Damasceno, A.4 aut
700a Langhorne, P.4 aut
700a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xrosan
700a Dans, A. L.4 aut
700a Elsayed, A.4 aut
700a Avezum, A.4 aut
700a Mondo, C.4 aut
700a Smyth, A.4 aut
700a Judge, C.4 aut
700a Diener, H. C.4 aut
700a Ryglewicz, D.4 aut
700a Czlonkowska, A.4 aut
700a Pogosova, N.4 aut
700a Weimar, C.4 aut
700a Iqbal, R.4 aut
700a Diaz, R.4 aut
700a Yusoff, K.4 aut
700a Yusufali, A.4 aut
700a Oguz, A.4 aut
700a Wang, X. Y.4 aut
700a Penaherrera, E.4 aut
700a Lanas, F.4 aut
700a Ogah, O. S.4 aut
700a Ogunniyi, A.4 aut
700a Iversen, H. K.4 aut
700a Malaga, G.4 aut
700a Rumboldt, Z.4 aut
700a Oveisgharan, S.4 aut
700a AlHussain, F.4 aut
700a Daliwonga, M.4 aut
700a Nilanont, Y.4 aut
700a Yusuf, S.4 aut
710a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
773t Heartd : BMJg 107:4, s. 282-289q 107:4<282-289x 1355-6037x 1468-201X
856u https://heart.bmj.com/content/heartjnl/107/4/282.full.pdf
8564 8u https://gup.ub.gu.se/publication/302573
8564 8u https://doi.org/10.1136/heartjnl-2019-316515

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