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FältnamnIndikatorerMetadata
00008330naa a2200853 4500
001oai:gup.ub.gu.se/307832
003SwePub
008240528s2021 | |||||||||||000 ||eng|
009oai:DiVA.org:oru-93518
009oai:lup.lub.lu.se:cce02fda-fb82-4741-9c57-b0635b1a7b48
009oai:DiVA.org:uu-455787
009oai:prod.swepub.kib.ki.se:234277969
0247 a https://gup.ub.gu.se/publication/3078322 URI
0247 a https://doi.org/10.1002/edm2.2442 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-935182 URI
0247 a https://lup.lub.lu.se/record/cce02fda-fb82-4741-9c57-b0635b1a7b482 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4557872 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:2342779692 URI
040 a (SwePub)gud (SwePub)orud (SwePub)lud (SwePub)uud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Sjölin, Gabriel,d 1979-u Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Fac Med & Hlth, Orebro, Sweden.4 aut0 (Swepub:oru)glsn
2451 0a Treatment of patients with Graves' disease in Sweden compared to international surveys of an 'index patient'
264 c 2021-03-16
264 1b Wiley,c 2021
520 a Introduction The treatment strategies for a 42-year-old female index patient with moderate Graves' disease (GD) vary according to several international surveys. The important question whether surveys of treatment preferences in theoretical patient cases also match how real patients are treated has not yet been addressed. Materials and Methods From a Swedish cohort of 1186 GD patients (TT-12 cohort), 27 women were identified using the same criteria as from the index patient surveys from the European and American Thyroid Associations. This 'index patient cohort' was age 40-45, otherwise healthy female, with two children and uncomplicated GD. The applied first-line treatment of the patients in the index cohort, together with its variations, was compared with the treatment preferences according to international surveys. A comparison with the TT-12 cohort was also performed. Results In the 'Index cohort', 77.8% were treated with antithyroid drugs (ATD), and 22.2% were treated with radioiodine (I-131). This preference for ATD is in line with most countries/regions, with the exception of USA and the Middle East/North Africa, where I-131 was preferred. The distribution of treatment in the TT-12 cohort did not significantly differ from the index cohort. ATD was the preferred treatment in male and young (age 19-22) patients, as was RAI in old (age 69-73) patients. The age-related, but not the gender-related, cases differed significantly from the entire TT-12 cohort. Conclusion The treatment choice in an index patient in Sweden seems in line with European practice, where ATD is the preferred first choice. This differs compared to US and North African survey intentions, where I-131 is more often used. Age more than gender influences the treatment choice of GD patients. This is, to our best knowledge, the first time an index patient from 'real life' has been presented and compared to treatment preferences of international thyroid association surveys.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653 a antithyroid drugs
653 a Graves' disease
653 a hyperthyroidism
653 a index patient
653 a international surveys
653 a long-term follow-up
653 a radioactive iodine
653 a thyroidectomy
653 a treatment options
653 a clinical-practice patterns
653 a case selection
653 a new-zealand
653 a management
653 a hyperthyroidism
653 a therapy
653 a ophthalmopathy
653 a diagnosis
653 a trends
653 a japan
653 a Endocrinology & Metabolism
653 a Graves’ disease
653 a Graves’ disease
7001 a Byström, Kristina,d 1961-u Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medicine Örebro University Hospital, Örebro, Sweden,Orebro Univ & Univ Hosp, Dept Med, Orebro, Sweden.4 aut0 (Swepub:oru)kbm
7001 a Holmberg, Mats,d 1958u University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden; ANOVA, Karolinska University Hospital, Stockholm, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Gothenburg, Sweden.;Karolinska Univ Hosp, ANOVA, Stockholm, Sweden.4 aut0 (Swepub:gu)xhmats
7001 a Torring, O.u Karolinska Institute,Karolinska Inst, Inst Clin Sci & Educ, Stockholm, Sweden.4 aut
7001 a Khamisi, Selwanu Uppsala universitet,Uppsala University,Uppsala University Hospital,Endokrinologi och mineralmetabolism4 aut0 (Swepub:uu)selkh262
7001 a Calissendorff, J.u Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Endocrinol Metab & Diabet, Stockholm, Sweden.4 aut
7001 a Lantz, Mikaelu Lund University,Lunds universitet,Translationell Muskel Forskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital,Skane Univ Hosp, Dept Endocrinol, Malmo, Sweden.;Lund Univ, Dept Clin Sci, Lund, Sweden.4 aut0 (Swepub:lu)endo-mla
7001 a Hallengren, Bengtu Lund University,Lunds universitet,Translationell Muskel Forskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital,Skane Univ Hosp, Dept Endocrinol, Malmo, Sweden.;Lund Univ, Dept Clin Sci, Lund, Sweden.4 aut0 (Swepub:lu)endo-bha
7001 a Nyström, Helena Filipsson,d 1966u University of Gothenburg,Gothenburg University,Göteborgs universitet,Wallenberg Centre for Molecular and Translational Medicine,Institutionen för medicin,Institute of Medicine,Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden; Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden; Wallenberg Center for Molecular and Translational Medicine, Göteborg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Endocrinol, Gothenburg, Sweden.;Wallenberg Ctr Mol & Translat Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xfilih
7001 a Planck, Terezau Lund University,Lunds universitet,Translationell Muskel Forskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital,Skane Univ Hosp, Dept Endocrinol, Malmo, Sweden.;Lund Univ, Dept Clin Sci, Lund, Sweden.4 aut0 (Swepub:lu)endo-tvo
7001 a Wallin, G.u Karolinska Institutet,Karolinska Institute,Örebro University Hospital,Orebro Univ Hosp, Fac Med & Hlth, Orebro, Sweden.;Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.4 aut
7102 a Faculty of Medicine and Health, Örebro University Hospital, Örebro, Swedenb Orebro Univ Hosp, Fac Med & Hlth, Orebro, Sweden.4 org
7730 t Endocrinology, Diabetes & Metabolismd : Wileyg 4:3q 4:3x 2398-9238
8564 u https://doi.org/10.1002/edm2.244
8564 u https://doi.org/10.1002/edm2.244y Fulltext
8564 u http://dx.doi.org/10.1002/edm2.244x freey FULLTEXT
8564 u https://uu.diva-portal.org/smash/get/diva2:1602383/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://gup.ub.gu.se/publication/307832
8564 8u https://doi.org/10.1002/edm2.244
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-93518
8564 8u https://lup.lub.lu.se/record/cce02fda-fb82-4741-9c57-b0635b1a7b48
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455787
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:234277969

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