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Long-term exposure ...
Long-term exposure to particulate air pollution and black carbon in relation to natural and cause-specific mortality: a multicohort study in Sweden
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- Nilsson Sommar, Johan (author)
- Umeå universitet,Avdelningen för hållbar hälsa
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- Andersson, Eva M., 1968 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden
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- Andersson, N. (author)
- Karolinska Institutet
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- Sällsten, Gerd, 1952 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden
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- Stockfelt, Leo, 1981 (author)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Danderyd Hospital, Stockholm, Sweden
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- Ljungman, P. L. S. (author)
- Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden
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- Segersson, D. (author)
- Swedish Meteorological and Hydrological Institute, Norrkoping, Sweden
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- Eneroth, K. (author)
- Karolinska Institutet
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- Gidhagen, L. (author)
- Swedish Meteorological and Hydrological Institute, Norrkoping, Sweden
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- Molnár, Peter, 1967 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden
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- Wennberg, Patrik, 1972- (author)
- Umeå universitet,Allmänmedicin
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- Rosengren, Annika, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Goteborg, Sweden
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- Rizzuto, D. (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Gerontology Research Centrum, Sweden
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- Leander, K. (author)
- Karolinska Institutet
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- Lager, A. (author)
- Karolinska Institutet
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Magnusson, P. K. E. (author)
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- Johansson, Christer (author)
- Stockholms universitet,Institutionen för miljövetenskap,Environment and Health Administration, Sweden
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- Barregård, Lars, 1948 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden
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- Bellander, T. (author)
- Karolinska Institutet
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- Pershagen, G. (author)
- Karolinska Institutet
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- Forsberg, Bertil, professor, 1956- (author)
- Umeå universitet,Avdelningen för hållbar hälsa
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(creator_code:org_t)
- 2021-09-08
- 2021
- English.
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In: Bmj Open. - : BMJ. - 2044-6055. ; 11:9
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Abstract
Subject headings
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- Objectives To estimate concentration-response relationships for particulate matter (PM) and black carbon (BC) in relation to mortality in cohorts from three Swedish cities with comparatively low pollutant levels. Setting Cohorts from Gothenburg, Stockholm and Umea, Sweden. Design High-resolution dispersion models were used to estimate annual mean concentrations of PM with aerodynamic diameter <= 10 mu m (PM10) and <= 2.5 mu m (PM2.5), and BC, at individual addresses during each year of follow-up, 1990-2011. Moving averages were calculated for the time windows 1-5 years (lag1-5) and 6-10 years (lag6-10) preceding the outcome. Cause-specific mortality data were obtained from the national cause of death registry. Cohort-specific HRs were estimated using Cox regression models and then meta-analysed including a random effect of cohort. Participants During the study period, 7 340 cases of natural mortality, 2 755 cases of cardiovascular disease (CVD) mortality and 817 cases of respiratory and lung cancer mortality were observed among in total 68 679 individuals and 689 813 person-years of follow-up. Results Both PM10 (range: 6.3-41.9 mu g/m(3)) and BC (range: 0.2-6.8 mu g/m(3)) were associated with natural mortality showing 17% (95% CI 6% to 31%) and 9% (95% CI 0% to 18%) increased risks per 10 mu g/m(3) and 1 mu g/m(3) of lag1-5 exposure, respectively. For PM2.5 (range: 4.0-22.4 mu g/m(3)), the estimated increase was 13% per 5 mu g/m(3), but less precise (95% CI -9% to 40%). Estimates for CVD mortality appeared higher for both PM10 and PM2.5. No association was observed with respiratory mortality. Conclusion The results support an effect of long-term air pollution on natural mortality and mortality in CVD with high relative risks also at low exposure levels. These findings are relevant for future decisions concerning air quality policies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- epidemiology
- public health
- cardiac epidemiology
- surface moisture model
- coupled road dust
- cardiovascular-disease
- lung-cancer
- emissions
- matter
- cohorts
- associations
- particles
- goteborg
- General & Internal Medicine
- cardiac epidemiology
Publication and Content Type
- ref (subject category)
- art (subject category)
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Nilsson Sommar, ...
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Andersson, Eva M ...
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Andersson, N.
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Sällsten, Gerd, ...
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Stockfelt, Leo, ...
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Ljungman, P. L. ...
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Segersson, D.
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Eneroth, K.
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Gidhagen, L.
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Molnár, Peter, 1 ...
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Wennberg, Patrik ...
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Rosengren, Annik ...
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Rizzuto, D.
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Leander, K.
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Lager, A.
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Magnusson, P. K. ...
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Johansson, Chris ...
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Barregård, Lars, ...
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Bellander, T.
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Pershagen, G.
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Forsberg, Bertil ...
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Bmj Open
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University of Gothenburg
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Umeå University
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Stockholm University
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Karolinska Institutet