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Case Report: Post-P...
Case Report: Post-Partum SARS-CoV-2 Infection After the First French Uterus Transplantation
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Ayoubi, Jean Marc (author)
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Carbonnel, Marie (author)
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- Kvarnström, Niclas (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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Revaux, Aurelie (author)
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Poulain, Marine (author)
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Vanlieferinghen, Sarah (author)
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Coatantiec, Yves (author)
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Le Marchand, Mathilde (author)
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Tourne, Morgan (author)
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Pirtea, Paul (author)
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Snanoudj, Renaud (author)
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Le Guen, Morgan (author)
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- Dahm-Kähler, Pernilla, 1964 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology
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Racowsky, Catherine (author)
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Brännström, Mats, 1958 (author)
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(creator_code:org_t)
- 2022-06-28
- 2022
- English.
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In: Frontiers in Surgery. - : Frontiers Media SA. - 2296-875X. ; 9
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Abstract
Subject headings
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- Absolute uterus factor infertility, whether congenital or acquired, renders the woman unable to carry a child. Although uterus transplantation (UTx) is being increasingly performed as a non-vital procedure to address this unfortunate condition, the immunosuppression required presents risks that are further compounded by pregnancy and during the puerperium period. These vulnerabilities require avoidance of SARS-CoV-2 infection in pregnant UTx recipients especially during the third trimester, as accumulating evidence reveals increased risks of morbidity and mortality. Here we describe a successful UTx case with delivery of a healthy child, but in which both mother and neonate developed asymptomatic SARS-CoV-2 infection seven days after RNA vaccination, on day 35 post-partum. Although the patient was successfully treated with a combination therapy comprised of two monoclonal antibodies, this case highlights the challenges associated with performing UTx in the era of Covid-19. More broadly, the risks of performing non-vital organ transplantation during a pandemic should be discussed among team members and prospective patients, weighing the risks against the benefits in improving the quality of life, which were considerable for our patient who achieved motherhood with the birth of a healthy child.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Keyword
- uterus transplantation
- immunotherapy
- COVID-19
- SARS-CoV-2
- case report
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Ayoubi, Jean Mar ...
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Carbonnel, Marie
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Kvarnström, Nicl ...
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Revaux, Aurelie
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Poulain, Marine
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Vanlieferinghen, ...
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show more...
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Coatantiec, Yves
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Le Marchand, Mat ...
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Tourne, Morgan
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Pirtea, Paul
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Snanoudj, Renaud
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Le Guen, Morgan
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Dahm-Kähler, Per ...
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Racowsky, Cather ...
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Brännström, Mats ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Obstetrics Gynae ...
- Articles in the publication
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Frontiers in Sur ...
- By the university
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University of Gothenburg