Search: onr:"swepub:oai:gup.ub.gu.se/326570" > A retrospective cas...
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000 | 03645naa a2200505 4500 | |
001 | oai:gup.ub.gu.se/326570 | |
003 | SwePub | |
008 | 240528s2023 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:152580303 | |
024 | 7 | a https://gup.ub.gu.se/publication/3265702 URI |
024 | 7 | a https://doi.org/10.1111/petr.145202 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1525803032 URI |
040 | a (SwePub)gud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Mellgren, Karin,d 1962u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics4 aut0 (Swepub:gu)xmellk |
245 | 1 0 | a A retrospective case-control study of gastrostomy use in children undergoing hematopoietic cell transplantation |
264 | 1 | c 2023 |
520 | a BackgroundMaintaining a good nutritional status during the hematopoietic cell transplantation (HCT) procedure is challenging in the pediatric population. MethodsIn a multicentric retrospective study, we compared the outcome of nutritional status and HCT-related parameters in 227 pediatric patients during and after HCT between 2005 and 2015. 112 patients received a gastrostomy before the start of HCT (GS group), and 115 did not receive a gastrostomy (NGS). Data collection was performed at HCT, 3, 6, and 12 months post-HCT. ResultsAt time point of HCT the Standard Deviation Score (SDS) of weight was 0.17 in the NGS group, and 0.71 in the GS group (p = .01) Patients in the NGS group lost more weight during the first 3 months after HCT than patients in the GS group. At 12 months, patients in the NGS remained at a lower weight, while patients in the GS group slightly increased their weight.There were no differences between the groups in the incidence of acute graft-versus-host-disease (GvHD), overall survival, and non-relapse mortality. However, the number of febrile episodes requiring intravenous treatment with antibiotics, was higher in the GS group as compared to the NGS group, during the first 3 months post-HCT (p < .001). ConclusionsOur results indicate that gastrostomy can be utilized in children undergoing HCT without any negative effects on mortality. Therefore, the use of a gastrostomy appears to be a safe option to maintain a good nutritional status during the HCT procedure. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
653 | a Hematopoietic stem cell transplantation | |
653 | a gastrostomy | |
653 | a nutritional | |
653 | a support | |
653 | a pediatric patients | |
653 | a pediatric-patients | |
653 | a cancer | |
653 | a nutrition | |
653 | a Pediatrics | |
653 | a Transplantation | |
700 | 1 | a Nicolajsen, T.4 aut |
700 | 1 | a Christoforaki, T. P.4 aut |
700 | 1 | a Juan, S. M.4 aut |
700 | 1 | a Martensson, T.4 aut |
700 | 1 | a Toporski, J.4 aut |
700 | 1 | a Casswall, T. H.u Karolinska Institutet4 aut |
700 | 1 | a Gustafsson, B.u Karolinska Institutet4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för pediatrik4 org |
773 | 0 | t Pediatric Transplantationg 27:4q 27:4x 1397-3142x 1399-3046 |
856 | 4 8 | u https://gup.ub.gu.se/publication/326570 |
856 | 4 8 | u https://doi.org/10.1111/petr.14520 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:152580303 |
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