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Oncolytic intralesi...
Oncolytic intralesional therapy for metastatic melanoma
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DePalo, D. K. (författare)
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Perez, M. C. (författare)
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- Huibers, Anne, 1986 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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- Olofsson Bagge, Roger, 1978 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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Zager, J. S. (författare)
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(creator_code:org_t)
- 2023
- 2023
- Engelska.
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Ingår i: Clinical & Experimental Metastasis. - 0262-0898.
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In-transit metastasis (ITM) develop in approximately 1 in 10 patients with melanoma and the disease course can vary widely. Surgical resection is the gold-standard treatment; however, ITM are often surgically unresectable due to size, distribution, and/or anatomic involvement. Oncolytic viral therapies are one category of non-surgical treatment options available for ITM. They induce tumor cell lysis and systemic anti-tumor activity through selective infection of tumor cells by naturally occurring or genetically modified factors. While there are numerous oncolytic viral therapies in various stages of development for the treatment of ITM, this discussion focuses on the mechanism and available literature for the two most established herpes virus-based therapies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Melanoma
- Metastatic melanoma
- Regional chemotherapy
- Intralesional
- oncolytic viral therapy intranist disease
- Regionally metastatic melanoma
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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