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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003178naa a2200313 4500
001oai:gup.ub.gu.se/54327
003SwePub
008240528s2007 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/543272 URI
024a https://doi.org/10.1080/028418606010160622 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Taheri-Kadkhoda, Zahra,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xtahza
2451 0a Long-term treatment results for nasopharyngeal carcinoma: the Sahlgrenska University Hospital experience.
264 c 2009-07-08
264 1b Informa UK Limited,c 2007
520 a Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. For evaluation of the treatment outcomes in our NPC patients, 52 new cases that were referred to our department between 1991 and 2002 were retrospectively analysed. Tumor stage, according to the 1997 AJCC staging system, was I in five, II in ten, III in 12 and IV in 25 patients. Majority of the patients (87%) had World Health Organization type II-III tumors. Neoadjuvant chemotherapy was delivered in 33 patients. Thirty-two patients received hyperfractionated accelerated radiation therapy with a median dose of 64.6Gy (1.7Gy/fr bid). Conventional external irradiation with a median dose of 66Gy (2Gy/fr) was delivered to 18 patients. An intracavitary brachy-boost of 4.5-12Gy was delivered to 40 patients. Two patients were excluded from the analysis due to treatment refusal. For the patients with tumor stages I-IVB, the 5-year disease-free and overall survival rates were 61% and 55%, respectively. The 5-year local, regional, and distant relapse-free survival rates were 70%, 92% and 77%, respectively. The most frequent late side effects were xerostomia (98%), otitis (70%) and hearing deterioration (64%). Our data suggest that optimization of the treatment outcomes in NPC patients requires implementation of new therapeutic strategies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
700a Björk-Eriksson, Thomas,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xbjoth
700a Johansson, Karl-Axelu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut
700a Mercke, Claes,d 1941u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xmercl
710a Göteborgs universitetb Institutionen för kliniska vetenskaper4 org
773t Acta oncologica (Stockholm, Sweden)d : Informa UK Limitedg 46:6, s. 817-27q 46:6<817-27x 0284-186Xx 1651-226X
8564 8u https://gup.ub.gu.se/publication/54327
8564 8u https://doi.org/10.1080/02841860601016062

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