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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04732naa a2200385 4500 | |
| 001 | oai:lup.lub.lu.se:10bb9485-a2a5-4e31-ab84-4606ce28838e | |
| 003 | SwePub | |
| 008 | 190619s1999 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/10bb9485-a2a5-4e31-ab84-4606ce28838e2 URI |
| 024 | 7 | a https://doi.org/10.1046/j.1365-2796.1999.00503.x2 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Larsson, Hilleviu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)extLU-1021 |
| 245 | 1 0 | a Habitual dietary intake versus glucose tolerance, insulin sensitivity and insulin secretion in postmenopausal women |
| 264 | c 2009-01-23 | |
| 264 | 1 | b Wiley,c 1999 |
| 300 | a 11 s. | |
| 520 | a Objective. The major aim was to study the relation between habitual dietary intake and glucose tolerance, insulin sensitivity and insulin secretion in postmenopausal women. Dietary intake was also compared between women with normal (NGT) or impaired glucose tolerance (IGT). Design. Habitual dietary intake was studied using a modified diet history method, from which the energy, carbohydrate, fat and protein intake was calculated. Glucose tolerance was determined as the 2 h glucose value after a 75 g oral glucose tolerance test. Insulin sensitivity was studied with a euglycemic, hyperinsulinaemic clamp, whilst insulin secretion was measured as the acute (2-5 min) response to iv arginine (5 g) at fasting, 14 and >25 mmol L-1 glucose. Setting. Clinical research unit at the University Hospital in Malmo Sweden. Subjects. A total of 74 women (mean ± SD age 58.7 ± 0.4 years). Results. In the entire group, the 2 h glucose level correlated with polyunsaturated fat intake (PUFA, r = 0.41, P < 0.001), and negatively with carbo- hydrate intake (r = -0.23, P = 0.05). The relation between 2 h glucose and PUFA was independent of body fat content and insulin sensitivity in a multivariate model. Insulin sensitivity correlated with energy intake (r = 0.31. P = 0.007) and PUFA (r = 0.27, P = 0.022). However, these correlations were not significant after adjustment for body fat content in a multivariate model. There were no correlations between insulin secretory variables and habitual dietary intake. Of the 74 women. 60 had NGT and 14 had IGT. The NGT and IGT groups did not differ in intakes of total energy, carbohydrate or protein. The IGT women had higher intake of PUFA (P = 0.003), whilst the total, saturated and monounsaturated fat intake did not differ between the groups. Conclusion. Dietary parameters are not independently associated with insulin sensitivity or insulin secretion in postmenopausal women. Furthermore, dietary habits are largely similar in women with NGT and IGT, although subtle differences cannot be excluded due to the small study size. Therefore, habitual intake of total carbohydrate or total fat seems not to be the major determinant of glucose tolerance in nondiabetic Caucasian postmenopausal women. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
| 653 | a Diet | |
| 653 | a Glucose tolerance | |
| 653 | a Insulin secretion | |
| 653 | a Insulin sensitivity | |
| 700 | 1 | a Elmstǎhl, S.u Lund University,Lunds universitet,Geriatrik,Forskargrupper vid Lunds universitet,Geriatric Medicine,Lund University Research Groups,Geriatrics,Skåne University Hospital4 aut0 (Swepub:lu)smi-sel |
| 700 | 1 | a Berglund, G.u Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-gbe |
| 700 | 1 | a Ahrén, B.u Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)med-bah |
| 710 | 2 | a Institutionen för kliniska vetenskaper, Malmöb Medicinska fakulteten4 org |
| 773 | 0 | t Journal of Internal Medicined : Wileyg 245:6, s. 581-591q 245:6<581-591x 1365-2796x 0954-6820 |
| 856 | 4 | u http://dx.doi.org/10.1046/j.1365-2796.1999.00503.xy FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/10bb9485-a2a5-4e31-ab84-4606ce28838e |
| 856 | 4 8 | u https://doi.org/10.1046/j.1365-2796.1999.00503.x |
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