Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer

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Fältnamn	Indikatorer	Metadata
000		05931naa a2201297 4500
001		oai:lup.lub.lu.se:17d4a50d-5191-471d-9c37-a29f10f75b76
003		SwePub
008		160401s2011 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:123295681
024	7	a https://lup.lub.lu.se/record/21795322 URI
024	7	a https://doi.org/10.1158/0008-5472.CAN-11-12662 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1232956812 URI
040		a (SwePub)lud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Stevens, Kristen N.4 aut
245	1 0	a Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer
264	1	c 2011
520		a Triple-negative breast cancers are an aggressive subtype of breast cancer with poor survival, but there remains little known about the etiologic factors that promote its initiation and development. Commonly inherited breast cancer risk factors identified through genome-wide association studies display heterogeneity of effect among breast cancer subtypes as defined by the status of estrogen and progesterone receptors. In the Triple Negative Breast Cancer Consortium (TNBCC), 22 common breast cancer susceptibility variants were investigated in 2,980 Caucasian women with triple-negative breast cancer and 4,978 healthy controls. We identified six single-nucleotide polymorphisms, including rs2046210 (ESR1), rs12662670 (ESR1), rs3803662 (TOX3), rs999737 (RAD51L1), rs8170 (19p13.1), and rs8100241 (19p13.1), significantly associated with the risk of triple-negative breast cancer. Together, our results provide convincing evidence of genetic susceptibility for triple-negative breast cancer. Cancer Res; 71(19); 6240-9. (C)2011 AACR.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
700	1	a Vachon, Celine M.4 aut
700	1	a Lee, Adam M.4 aut
700	1	a Slager, Susanu Karolinska Institutet4 aut
700	1	a Lesnick, Timothy4 aut
700	1	a Olswold, Curtis4 aut
700	1	a Fasching, Peter A.4 aut
700	1	a Miron, Penelope4 aut
700	1	a Eccles, Diana4 aut
700	1	a Carpenter, Jane E.4 aut
700	1	a Godwin, Andrew K.4 aut
700	1	a Ambrosone, Christine4 aut
700	1	a Winqvist, Robert4 aut
700	1	a Brauch, Hiltrud4 aut
700	1	a Schmidt, Marjanka K.4 aut
700	1	a Cox, Angela4 aut
700	1	a Cross, Simon S.4 aut
700	1	a Sawyer, Elinor4 aut
700	1	a Hartmann, Arndt4 aut
700	1	a Beckmann, Matthias W.4 aut
700	1	a Schulz-Wendtland, Ruediger4 aut
700	1	a Ekici, Arif B.4 aut
700	1	a Tapper, William J.4 aut
700	1	a Gerty, Susan M.4 aut
700	1	a Durcan, Lorraine4 aut
700	1	a Graham, Nikki4 aut
700	1	a Hein, Rebecca4 aut
700	1	a Nickels, Stephan4 aut
700	1	a Flesch-Janys, Dieter4 aut
700	1	a Heinz, Judith4 aut
700	1	a Sinn, Hans-Peter4 aut
700	1	a Konstantopoulou, Irene4 aut
700	1	a Fostira, Florentia4 aut
700	1	a Pectasides, Dimitrios4 aut
700	1	a Dimopoulos, Athanasios M.4 aut
700	1	a Fountzilas, George4 aut
700	1	a Clarke, Christine L.4 aut
700	1	a Balleine, Rosemary4 aut
700	1	a Olson, Janet E.4 aut
700	1	a Fredericksen, Zachary4 aut
700	1	a Diasio, Robert B.4 aut
700	1	a Pathak, Harsh4 aut
700	1	a Ross, Eric4 aut
700	1	a Weaver, JoEllen4 aut
700	1	a Ruediger, Thomas4 aut
700	1	a Försti, Astau Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-asf
700	1	a Duennebier, Thomas4 aut
700	1	a Ademuyiwa, Foluso4 aut
700	1	a Kulkarni, Swati4 aut
700	1	a Pylkaes, Katri4 aut
700	1	a Jukkola-Vuorinen, Arja4 aut
700	1	a Ko, Yon-Dschun4 aut
700	1	a Van Limbergen, Erik4 aut
700	1	a Janssen, Hilde4 aut
700	1	a Peto, Julian4 aut
700	1	a Fletcher, Olivia4 aut
700	1	a Giles, Graham G.4 aut
700	1	a Baglietto, Laura4 aut
700	1	a Verhoef, Senno4 aut
700	1	a Tomlinson, Ian4 aut
700	1	a Kosma, Veli-Matti4 aut
700	1	a Beesley, Jonathan4 aut
700	1	a Greco, Dario4 aut
700	1	a Blomqvist, Carl4 aut
700	1	a Irwanto, Astrid4 aut
700	1	a Liu, Jianjun4 aut
700	1	a Blows, Fiona M.4 aut
700	1	a Dawson, Sarah-Jane4 aut
700	1	a Margolin, Sara4 aut
700	1	a Mannermaa, Arto4 aut
700	1	a Martin, Nicholas G.4 aut
700	1	a Montgomery, Grant W.4 aut
700	1	a Lambrechts, Diether4 aut
700	1	a Silva, Isabel dos Santos4 aut
700	1	a Severi, Gianluca4 aut
700	1	a Hamann, Ute4 aut
700	1	a Pharoah, Paul4 aut
700	1	a Easton, Douglas F.4 aut
700	1	a Chang-Claude, Jenny4 aut
700	1	a Yannoukakos, Drakoulis4 aut
700	1	a Nevanlinna, Heli4 aut
700	1	a Wang, Xianshu4 aut
700	1	a Couch, Fergus J.4 aut
710	2	a Karolinska Institutetb Allmänmedicin och klinisk epidemiologi4 org
773	0	t Cancer Researchg 71:19, s. 6240-6249q 71:19<6240-6249x 1538-7445
856	4	u http://dx.doi.org/10.1158/0008-5472.CAN-11-1266y FULLTEXT
856	4 8	u https://lup.lub.lu.se/record/2179532
856	4 8	u https://doi.org/10.1158/0008-5472.CAN-11-1266
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:123295681

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Av författaren/redakt...: Stevens, Kristen ...; Vachon, Celine M ...; Lee, Adam M.; Slager, Susan; Lesnick, Timothy; Olswold, Curtis; visa fler...; Fasching, Peter ...; Miron, Penelope; Eccles, Diana; Carpenter, Jane ...; Godwin, Andrew K ...; Ambrosone, Chris ...; Winqvist, Robert; Brauch, Hiltrud; Schmidt, Marjank ...; Cox, Angela; Cross, Simon S.; Sawyer, Elinor; Hartmann, Arndt; Beckmann, Matthi ...; Schulz-Wendtland ...; Ekici, Arif B.; Tapper, William ...; Gerty, Susan M.; Durcan, Lorraine; Graham, Nikki; Hein, Rebecca; Nickels, Stephan; Flesch-Janys, Di ...; Heinz, Judith; Sinn, Hans-Peter; Konstantopoulou, ...; Fostira, Florent ...; Pectasides, Dimi ...; Dimopoulos, Atha ...; Fountzilas, Geor ...; Clarke, Christin ...; Balleine, Rosema ...; Olson, Janet E.; Fredericksen, Za ...; Diasio, Robert B ...; Pathak, Harsh; Ross, Eric; Weaver, JoEllen; Ruediger, Thomas; Försti, Asta; Duennebier, Thom ...; Ademuyiwa, Folus ...; Kulkarni, Swati; Pylkaes, Katri; Jukkola-Vuorinen ...; Ko, Yon-Dschun; Van Limbergen, E ...; Janssen, Hilde; Peto, Julian; Fletcher, Olivia; Giles, Graham G.; Baglietto, Laura; Verhoef, Senno; Tomlinson, Ian; Kosma, Veli-Matt ...; Beesley, Jonatha ...; Greco, Dario; Blomqvist, Carl; Irwanto, Astrid; Liu, Jianjun; Blows, Fiona M.; Dawson, Sarah-Ja ...; Margolin, Sara; Mannermaa, Arto; Martin, Nicholas ...; Montgomery, Gran ...; Lambrechts, Diet ...; Silva, Isabel do ...; Severi, Gianluca; Hamann, Ute; Pharoah, Paul; Easton, Douglas ...; Chang-Claude, Je ...; Yannoukakos, Dra ...; Nevanlinna, Heli; Wang, Xianshu; Couch, Fergus J.; visa färre...

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