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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03849naa a2200325 4500 | |
| 001 | oai:lup.lub.lu.se:2dfb8eb5-de6b-414c-a6e3-3e30f030f00e | |
| 003 | SwePub | |
| 008 | 180926s2018 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/2dfb8eb5-de6b-414c-a6e3-3e30f030f00e2 URI |
| 024 | 7 | a https://doi.org/10.1080/10641955.2018.15162252 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a von Wowern, Emmau Lund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-evr |
| 245 | 1 0 | a Arterial stiffness during controlled ovarian hyperstimulation and early pregnancy in women exposed to assisted reproduction |
| 264 | c 2018-09-21 | |
| 264 | 1 | b Informa UK Limited,c 2018 |
| 520 | a INTRODUCTION: Female sex hormones have vasorelaxing effects in non-pregnant and pregnant women. We aimed to investigate the effect of controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF), and early pregnancy, on arterial stiffness as assessed by digital pulse wave analysis (DPA), hypothesizing reduced arterial stiffness as an effect of increased estrogen levels.MATERIAL AND METHODS: A total of 68 women undergoing IVF were examined with DPA before conception and during IVF treatment with COH and embryo transfer (ET), and in gestational week seven in 19 women who became pregnant. Heart rate (HR), mean arterial pressure (MAP) and the DPA variables cardiac ejection elasticity index (EEI), b/a, dicrotic index (DI), d/a and aging index (AI) were measured.RESULTS: HR was significantly increased at all measuring points (p ≤ 0.003) but MAP only at ET (p 0.007). DPA variables representing large arteries (EEI, b/a) and peripheral arteries (DI, but not d/a), and the global variable AI, indicated increased arterial stiffness at ET compared with baseline (p ≤ 0.035). No DPA variable was significantly changed at pregnancy measurements compared to baseline.CONCLUSION: During COH for IVF treatment, DPA showed no changes in arterial stiffness during the follicular phase or in early pregnancy, but increased arterial stiffness in central and peripheral arteries in the early luteal phase. The result suggests a hormonal hemodynamic activation counteracting the effects of estrogen. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 700 | 1 | a Saldeen, Piau Lund University,Lunds universitet,Reproduktionsmedicin, Malmö,Forskargrupper vid Lunds universitet,Reproductive medicine, Malmö,Lund University Research Groups,Nordic IVF Malmö4 aut0 (Swepub:lu)med-psl |
| 700 | 1 | a Olofsson, Peru Lund University,Lunds universitet,Urogynekologi och reproduktionsfarmakologi,Forskargrupper vid Lunds universitet,Urogynaecology and Reproductive Pharmacology,Lund University Research Groups,Cura Mödravård, Malmö4 aut0 (Swepub:lu)obst-pol |
| 710 | 2 | a Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostikb Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t Hypertension in Pregnancyd : Informa UK Limitedg 37:4, s. 182-191q 37:4<182-191x 1064-1955x 1525-6065 |
| 856 | 4 | u http://dx.doi.org/10.1080/10641955.2018.1516225x freey FULLTEXT |
| 856 | 4 | u https://www.tandfonline.com/doi/pdf/10.1080/10641955.2018.1516225?needAccess=true |
| 856 | 4 8 | u https://lup.lub.lu.se/record/2dfb8eb5-de6b-414c-a6e3-3e30f030f00e |
| 856 | 4 8 | u https://doi.org/10.1080/10641955.2018.1516225 |
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