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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005232naa a2200373 4500
001oai:lup.lub.lu.se:33796528-c21b-48b6-bf73-66e6da7c13a8
003SwePub
008220919s2022 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/33796528-c21b-48b6-bf73-66e6da7c13a82 URI
0247 a https://doi.org/10.1111/ane.136852 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Apostolaki-Hansson, Trineu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Stroke policy och kvalitetsregisterforskning,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Stroke policy and quality register research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)tr5046ap
2451 0a Patient factors associated with receiving reversal therapy in oral anticoagulant-related intracerebral hemorrhage
264 c 2022-08-16
264 1b Hindawi Limited,c 2022
520 a Background: We aimed to describe baseline characteristics of patients with oral anticoagulant-related intracerebral hemorrhage (OAC-ICH) in Sweden and to identify predictive variables associated with receiving hemostatic treatment in the event of OAC-ICH. Methods: We performed an observational study based on data from Riksstroke and the Swedish Causes of Death Register to define baseline characteristics of patients with OAC-ICH who received reversal treatment compared with patients who did not receive reversal treatment during 2017–2019. Predictive analysis was performed using multivariable logistic regression to identify odds ratios for factors associated with receiving OAC reversal treatment. Results: We included 1902 patients ((n = 1146; OAC reversal treatment) (n = 756; no OAC reversal treatment)). The proportion of non-Vitamin K oral anticoagulant associated ICH (NOAC-ICH) patients who received reversal treatment was 48.4% and the proportion of Vitamin K antagonist-associated ICH (VKA-ICH) patients was 72.9%. Factors associated with a lower odds of receiving reversal treatment were increased age (OR = 0.98; 95% CI: 0.96–0.99), previous stroke (OR = 0.78; 95% CI: 0.62–0.98), comatose LOC (OR = 0.36;95%CI: 0.27–0.48; ref. = alert), pre-stroke dependency (OR = 0.72; 95% CI: 0.58–0.91), and NOAC treatment (OR = 0.34; 95% CI: 0.28–0.42). Care at a university hospital was not associated with higher odds of receiving reversal treatment compared to treatment at a county hospital. Conclusion: Treatment with a reversal agent following OAC-ICH was related to several patient factors including type of OAC drug. We identified that only 48% of patients with NOAC-ICH received hemostatic treatment despite an increase in these cases. Further studies are required to guide the use of reversal therapies more precisely, particularly in NOAC-ICH.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a intracerebral hemorrhage
653 a non-vitamin K oral anticoagulant
653 a oral anticoagulant drug
653 a reversal therapy
7001 a Ullberg, Teresau Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Stroke policy och kvalitetsregisterforskning,Forskargrupper vid Lunds universitet,Stroke Imaging Research group,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Stroke policy and quality register research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-tsu
7001 a Norrving, Bou Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Klinisk strokeforskning,Forskargrupper vid Lunds universitet,Stroke policy och kvalitetsregisterforskning,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Clinical Stroke Research Group,Lund University Research Groups,Stroke policy and quality register research,Skåne University Hospital4 aut0 (Swepub:lu)neur-bno
7001 a Petersson, Jesperu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Stroke policy och kvalitetsregisterforskning,Forskargrupper vid Lunds universitet,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Stroke policy and quality register research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)neur-jpe
7102 a Neurologi, Lundb Sektion IV4 org
7730 t Acta Neurologica Scandinavicad : Hindawi Limitedg 146:5, s. 590-597q 146:5<590-597x 0001-6314x 1600-0404
8564 u http://dx.doi.org/10.1111/ane.13685x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/33796528-c21b-48b6-bf73-66e6da7c13a8
8564 8u https://doi.org/10.1111/ane.13685

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