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Clinical manifestat...
Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohort
- Article/chapterEnglish2007
Publisher, publication year, extent ...
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2016-07-02
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SAGE Publications,2007
Numbers
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LIBRIS-ID:oai:lup.lub.lu.se:6f53fca0-55e9-4808-b229-cfbe4f6bf436
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https://lup.lub.lu.se/record/1142696URI
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https://doi.org/10.1177/0961203307081113DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:116048881URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:art swepub-publicationtype
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Subject category:ref swepub-contenttype
Notes
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Systemic Lupus International Collaborating Clinics (SLICC) comprises 27 centres from 11 countries. An inception cohort of 918 SLE patients has been assembled according to a standardized protocol between 2000 and 2006. Clinical features, classic coronary artery disease (CAD) risk factors, as well as other potential risk factors were collected. Of the 918 patients 89% were females, and of multi racial origin. Less than half the patients were living in a permanent relationship, 58% had post secondary education and 51% were employed. Eight percent had family history of SLE. At enrolment, with at mean age of diagnosis of 34.5 years, a significant number of patients already had CAD risk factors, such as hypertension (33%) and hypercholesterolemia (36%). Only 15% of the patients were postmenopausal, 16% were current smokers and 3.6% had diabetes at entry to the SLICC-RAS (Registry for Atherosclerosis). A number of patients in this multi-racial, multi-ethnic inception cohort of lupus patients have classic CAD risk factors within a mean of 5.4 months from diagnosis. This cohort will be increased to 1500 patients to be followed yearly for 10 years. This will provide a unique opportunity to evaluate risk factors for accelerated atherosclerosis in SLE.
Subject headings and genre
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Gladman, D
(author)
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Ibanez, D
(author)
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Fortin, P
(author)
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Sanchez-Guerrero, J
(author)
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Bae, S
(author)
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Clarke, A
(author)
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Bernatsky, S
(author)
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Gordon, C
(author)
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Hanly, J
(author)
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Wallace, D
(author)
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Isenberg, D
(author)
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Ginzler, E
(author)
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Merrill, J
(author)
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Alarcon, G
(author)
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Steinsson, K
(author)
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Petri, M
(author)
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Dooley, M A
(author)
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Bruce, I
(author)
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Manzi, S
(author)
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Khamashta, M
(author)
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Ramsey-Goldman, R
(author)
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Zoma, A
(author)
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Sturfelt, GunnarLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)reum-gst
(author)
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Nived, OlaLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)reum-oni
(author)
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Maddison, P
(author)
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Font, J
(author)
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van Vollenhoven, RKarolinska Institutet
(author)
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Aranow, C
(author)
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Kalunian, K
(author)
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Stoll, T
(author)
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Buyon, J
(author)
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Reumatologi och molekylär skelettbiologiSektion III
(creator_code:org_t)
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In:Lupus: SAGE Publications16:9, s. 731-7350961-20331477-0962
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Urowitz, M B
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Gladman, D
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Ibanez, D
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Fortin, P
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Sanchez-Guerrero ...
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Bae, S
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Clarke, A
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Bernatsky, S
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Gordon, C
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Hanly, J
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Wallace, D
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Isenberg, D
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Ginzler, E
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Merrill, J
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Alarcon, G
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Steinsson, K
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Petri, M
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Dooley, M A
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Bruce, I
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Manzi, S
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Khamashta, M
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Ramsey-Goldman, ...
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Zoma, A
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Sturfelt, Gunnar
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Nived, Ola
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Maddison, P
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Font, J
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van Vollenhoven, ...
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Aranow, C
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Kalunian, K
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Stoll, T
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Buyon, J
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Lupus
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