onr:"swepub:oai:lup.lub.lu.se:829ae736-8136-4d5a-aeb2-63766383fbc4"
Sökning: onr:"swepub:oai:lup.lub.lu.se:829ae736-8136-4d5a-aeb2-63766383fbc4" > Immunoreactive tryp...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07059naa a2200913 4500 | |
| 001 | oai:lup.lub.lu.se:829ae736-8136-4d5a-aeb2-63766383fbc4 | |
| 003 | SwePub | |
| 008 | 190911s1990 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/829ae736-8136-4d5a-aeb2-63766383fbc42 URI |
| 024 | 7 | a https://doi.org/10.1097/00006676-199005000-000012 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Landin-Olsson, Monau Skåne University Hospital4 aut0 (Swepub:lu)med-mla |
| 245 | 1 0 | a Immunoreactive trypsin(Ogen) in the sera of children with recent-onset insulin-dependent diabetes and matched controls |
| 264 | 1 | b Ovid Technologies (Wolters Kluwer Health),c 1990 |
| 520 | a To evaluate the exocrine pancreatic function at the time of diagnosis of insulin-dependent diabetes mellitus, we determined immunoreactive an-odal and cathodal trypsin(ogen) levels in sera from almost all children (n = 375) 0-14 years of age in Sweden in whom diabetes developed during 1 year, and in sex-, age-, and geographically matched control subjects (n = 312). The median level of anodal trypsin(ogen) was 5 (quartile range, 3-7) µg/L in children with newly diagnosed diabetes, compared with a median level of 7 (quartile range, 4-8) µg/L in control subjects (p < 0.0001). Similarly, the median level of cathodal trypsin(ogen) was 8 (quartile range, 4-10) µg/L in children with diabetes, compared with a median level of 11 (quartile range, 7-15) µg/L in control subjects (p < 0.0001). The median of the individual ratios between cathodal and anodal trypsin(ogen) was 1.4 in the diabetic patients and 1.7 in the control children (p < 0.001). In a multivariate test, however, only the decrease in cathodal trypsin(ogen) concentration was associated with diabetes. The levels of trypsin(ogen)s did not correlate with levels of islet cell antibodies, present in 81% of the diabetic children. Several mechanisms may explain our findings, for example, similar pathogenetic factors may affect both the endocrine and exocrine pancreas simultaneously, a failing local trophic stimulation by insulin on the exocrine cells may decrease the trypsinogen production, and there may be an increased elimination of trypsin(ogen) because of higher filtration through the kidneys in the hyperglycemic state. | |
| 653 | a Anodal trypsin-(ogen) | |
| 653 | a Case-control study | |
| 653 | a Cathodal trypsin(ogen) | |
| 653 | a Exocrine pancreatic function | |
| 653 | a Insulin-dependent diabetic children | |
| 700 | 1 | a Borgstrom, Anders4 aut |
| 700 | 1 | a Blom, Leifu Lund University,Lunds universitet,Pediatrisk endokrinologi,Forskargrupper vid Lunds universitet,Paediatric Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)pedi-lbl |
| 700 | 1 | a Sundkvist, Goran4 aut |
| 700 | 1 | a Lernmark, Akeu Lund University4 aut0 (Swepub:lu)endo-ale |
| 700 | 1 | a Nyström, L.u Umeå University4 aut |
| 700 | 1 | a Sandström, A.u Umeå University4 aut |
| 700 | 1 | a Wall, S.u Umeå University4 aut |
| 700 | 1 | a Aili, M.4 aut |
| 700 | 1 | a Bäckman, H.4 aut |
| 700 | 1 | a Carlsson, E.u Lund University4 aut0 (Swepub:lu)em0728ca |
| 700 | 1 | a Edenwall, H.4 aut |
| 700 | 1 | a Elfstrand, P. O.4 aut |
| 700 | 1 | a Granström, B. W.4 aut |
| 700 | 1 | a Gustavsson, I.4 aut |
| 700 | 1 | a Gustavsson, L. E.4 aut |
| 700 | 1 | a Hallberg, A.4 aut |
| 700 | 1 | a Hansing, B.4 aut |
| 700 | 1 | a Hanås, R.4 aut |
| 700 | 1 | a Hellenberg, L.4 aut |
| 700 | 1 | a Holmberg, E.4 aut |
| 700 | 1 | a Hornell, H.4 aut |
| 700 | 1 | a Jonsell, G.4 aut |
| 700 | 1 | a Jönsson, C.4 aut |
| 700 | 1 | a Kockum, K.4 aut |
| 700 | 1 | a Lindberg, U.u Lund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Autoimmunitet och njursjukdomar,Forskargrupper vid Lunds universitet,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Autoimmunity and kidney diseases,Lund University Research Groups4 aut0 (Swepub:lu)med-ukl |
| 700 | 1 | a Lindblad, B.u Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups4 aut0 (Swepub:lu)kir-bli |
| 700 | 1 | a Ludvigsson, J.4 aut |
| 700 | 1 | a Mazreliez, V.4 aut |
| 700 | 1 | a Myrdal, U.4 aut |
| 700 | 1 | a Neiderud, J.u Lund University,Lunds universitet,Kliniska Vetenskaper, Helsingborg,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Sciences, Helsingborg,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-jnu |
| 700 | 1 | a Nilsson, K. O.u Lund University,Lunds universitet,Pediatrisk endokrinologi,Forskargrupper vid Lunds universitet,Paediatric Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-kfn |
| 700 | 1 | a Persson, B.u Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)med-bop |
| 700 | 1 | a Petzén, P. G.4 aut |
| 700 | 1 | a Samuelsson, G.u Lund University,Lunds universitet,Institutionen för hälsovetenskaper,Medicinska fakulteten,Hållbar vardag och hälsa i ett livsperspektiv,Forskargrupper vid Lunds universitet,Vård i högteknologisk miljö,Department of Health Sciences,Faculty of Medicine,Sustainable occupations and health in a life course perspective,Lund University Research Groups,Care in high technological environments4 aut0 (Swepub:lu)gero-gsa |
| 700 | 1 | a Segnestam, K.4 aut |
| 700 | 1 | a Sigurs, N.4 aut |
| 700 | 1 | a Sjöblad, S.u Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)st6585sj |
| 700 | 1 | a Sjögren, S.4 aut |
| 700 | 1 | a Skogsberg, L.4 aut |
| 700 | 1 | a Smith, T.4 aut |
| 700 | 1 | a Snellman, K.4 aut |
| 700 | 1 | a Strömberg, L.4 aut |
| 700 | 1 | a Ståle, U.4 aut |
| 700 | 1 | a Tenstam, J.4 aut |
| 700 | 1 | a Thalme, B.4 aut |
| 700 | 1 | a Thilén, A.4 aut |
| 700 | 1 | a Tullus, K.4 aut |
| 700 | 1 | a Tuvemo, T.4 aut |
| 700 | 1 | a Westphal, O.4 aut |
| 710 | 2 | a Skåne University Hospitalb Pediatrisk endokrinologi4 org |
| 710 | 2 | a The Swedish Childhood Diabetes Group |
| 773 | 0 | t Pancreasd : Ovid Technologies (Wolters Kluwer Health)g 5:3, s. 241-247q 5:3<241-247x 0885-3177 |
| 856 | 4 | u http://dx.doi.org/10.1097/00006676-199005000-00001y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/829ae736-8136-4d5a-aeb2-63766383fbc4 |
| 856 | 4 8 | u https://doi.org/10.1097/00006676-199005000-00001 |
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Landin-Olsson, M ...
- Borgstrom, Ander ...
- Blom, Leif
- Sundkvist, Goran
- Lernmark, Ake
- Nyström, L.
- visa fler...
- Sandström, A.
- Wall, S.
- Aili, M.
- Bäckman, H.
- Carlsson, E.
- Edenwall, H.
- Elfstrand, P. O.
- Granström, B. W.
- Gustavsson, I.
- Gustavsson, L. E ...
- Hallberg, A.
- Hansing, B.
- Hanås, R.
- Hellenberg, L.
- Holmberg, E.
- Hornell, H.
- Jonsell, G.
- Jönsson, C.
- Kockum, K.
- Lindberg, U.
- Lindblad, B.
- Ludvigsson, J.
- Mazreliez, V.
- Myrdal, U.
- Neiderud, J.
- Nilsson, K. O.
- Persson, B.
- Petzén, P. G.
- Samuelsson, G.
- Segnestam, K.
- Sigurs, N.
- Sjöblad, S.
- Sjögren, S.
- Skogsberg, L.
- Smith, T.
- Snellman, K.
- Strömberg, L.
- Ståle, U.
- Tenstam, J.
- Thalme, B.
- Thilén, A.
- Tullus, K.
- Tuvemo, T.
- Westphal, O.
- visa färre...
- Artiklar i publikationen
- Pancreas
- Av lärosätet
- Lunds universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
