Sökning: onr:"swepub:oai:lup.lub.lu.se:8dad66d1-99ab-44dc-8ec8-f3dc96a4470f" > General and abdomin...
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000 | 06712naa a2200805 4500 | |
001 | oai:lup.lub.lu.se:8dad66d1-99ab-44dc-8ec8-f3dc96a4470f | |
003 | SwePub | |
008 | 190222s2019 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-162023 | |
024 | 7 | a https://lup.lub.lu.se/record/8dad66d1-99ab-44dc-8ec8-f3dc96a4470f2 URI |
024 | 7 | a https://doi.org/10.1016/j.parkreldis.2019.01.0192 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1620232 URI |
040 | a (SwePub)lud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Riso, Lukasu German Cancer Research Centre4 aut |
245 | 1 0 | a General and abdominal adiposity and the risk of Parkinson's disease : A prospective cohort study |
264 | 1 | b Elsevier BV,c 2019 |
520 | a Introduction: Due to demographic change, an increase in the frequency of Parkinson's disease (PD) patients is expected in the future and, thus, the identification of modifiable risk factors is urgently needed. We aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with incident PD. Methods: In 13 of the 23 centers of the European Prospective Investigation into Cancer and Nutrition (EPIC) study, a total of 734 incident cases of PD were identified between 1992 and 2012 with a mean follow-up of 12 years. Cox proportional hazards regression was used to calculate hazard ratios (HR) with 95% confidence intervals (CI). We modelled anthropometric variables as continuous and categorical exposures and performed subgroup analyses by potential effect modifiers including sex and smoking. Results: We found no association between BMI, WC and incident PD, neither among men nor among women. Among never and former smokers, BMI and waist circumference were also not associated with PD risk. For male smokers, however, we observed a statistically significant inverse association between BMI and PD risk (HR 0.51, 95%CI: 0.30, 0.84) and the opposite for women, i.e. a significant direct association of BMI (HR 1.79, 95%CI: 1.04, 3.08) and waist circumference (HR 1.64, 95%CI: 1.03, 2.61) with risk of PD. Conclusion: Our data revealed no association between excess weight and PD risk but a possible interaction between anthropometry, sex and smoking. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng |
653 | a BMI | |
653 | a Cohort | |
653 | a EPIC | |
653 | a Overweight | |
653 | a Parkinson | |
653 | a Smoking | |
653 | a Parkinson | |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Kühn, Tilmanu German Cancer Research Centre4 aut |
700 | 1 | a Sookthai, Disornu German Cancer Research Centre4 aut |
700 | 1 | a Forsgren, Larsu Umeå universitet,Umeå University,Klinisk neurovetenskap,Enheten för biobanksforskning4 aut0 (Swepub:umu)lafo0001 |
700 | 1 | a Trupp, Milesu Umeå universitet,Umeå University,Klinisk neurovetenskap,Enheten för biobanksforskning4 aut0 (Swepub:umu)mitr0006 |
700 | 1 | a Trichopoulou, Antoniau Hellenic Health Foundation, Athens4 aut |
700 | 1 | a La Vecchia, Carlou Hellenic Health Foundation, Athens,University of Milan4 aut |
700 | 1 | a Karakatsani, Annau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Gavrila, Dianau Murcia Regional Health Council,CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Freisling, Heinzu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Petersson, Jesperu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)neur-jpe |
700 | 1 | a Lewan, Susanneu Lund University4 aut |
700 | 1 | a Vermeulen, Roel CHu University Medical Center Utrecht,Utrecht University4 aut |
700 | 1 | a Panico, Salvatoreu University of Naples Federico II4 aut |
700 | 1 | a Masala, Giovannau Cancer Research and Prevention Institute (ISPO)4 aut |
700 | 1 | a Ardanaz, Evau CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)4 aut0 (Swepub:lu)extLU-05 |
700 | 1 | a Krogh, Vittoriou Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Perneczky, Robert G.u Imperial College London,University Hospital Munich,German Center for Neurodegenerative Diseases (DZNE), Bonn4 aut |
700 | 1 | a Middleton, Lefkos T.u Imperial College London4 aut |
700 | 1 | a Mokoroa, Olatzu Biodonostia Health Research Institute4 aut |
700 | 1 | a Sacerdote, Carlottau Citta' della Salute e della Scienza Hospital-University of Turin,Centre for Cancer Epidemiology and Prevention (CPO Piemonte)4 aut |
700 | 1 | a Sieri, Sabrinau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Hayat, Shabina A.u University of Cambridge4 aut |
700 | 1 | a Brayne, Carolu University of Cambridge4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
700 | 1 | a Vineis, Paolou Imperial College London4 aut |
700 | 1 | a Gallo, Valentinau Imperial College London,Queen Mary University4 aut |
700 | 1 | a Katzke, Verena A.u German Cancer Research Centre4 aut |
710 | 2 | a Umeå Universityb German Cancer Research Centre4 org |
773 | 0 | t Parkinsonism and Related Disordersd : Elsevier BVg 62, s. 98-104q 62<98-104x 1353-8020x 1873-5126 |
856 | 4 | u http://dx.doi.org/10.1016/j.parkreldis.2019.01.019y FULLTEXT |
856 | 4 | u https://qmro.qmul.ac.uk/xmlui/bitstream/123456789/55363/6/Gallo_GENERAL%20AND%20ABDOMINAL%20ADIPOSITY_accepted%20manuscript_2019.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/8dad66d1-99ab-44dc-8ec8-f3dc96a4470f |
856 | 4 8 | u https://doi.org/10.1016/j.parkreldis.2019.01.019 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-162023 |
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