Search: onr:"swepub:oai:lup.lub.lu.se:a6411fa9-ac77-4b8a-bf99-261a73ad3818" > Production of an am...
Fältnamn | Indikatorer | Metadata |
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000 | 04004naa a2200481 4500 | |
001 | oai:lup.lub.lu.se:a6411fa9-ac77-4b8a-bf99-261a73ad3818 | |
003 | SwePub | |
008 | 211026s1987 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/a6411fa9-ac77-4b8a-bf99-261a73ad38182 URI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Grubb, Andersu Lund University,Lunds universitet,Avdelningen för klinisk kemi och farmakologi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Cystatin C, njursjukdom, amyloidos och antibiotika,Forskargrupper vid Lunds universitet,Division of Clinical Chemistry and Pharmacology,Department of Laboratory Medicine,Faculty of Medicine,Cystatin C, renal disease, amyloidosis and antibiotics,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kkem-agr |
245 | 1 0 | a Production of an amino acid sequence-specific antiserum against human amyloid A (AA) and serum amyloid A (SAA) protein |
264 | 1 | c 1987 |
300 | a 8 s. | |
520 | a The hydrophilic nonapeptide Ser-Asp-Ala-Arg-Glu-Asn-Ile-Gln-Arg, identical with residues 59-67 of human amyloid protein A (AA) and serum amyloid protein A (SAA), was covalently bound via its carboxyl-terminal end to the carrier-protein keyhole limpet haemocyanin. The complex was injected subcutaneously into ten rabbits. All rabbits produced antisera which, unabsorbed, were specific for AA and SAA. The antisera and their isolated peptide specific antibodies were performance-tested and found to be excellent for demonstration of AA and SAA in immunoblotting and immunohistochemical techniques but unsuitable for immunoprecipitation. Since it is difficult to produce AA- and SAA-specific antisera by procedures earlier described and commercial supplies of good such reagents are unavailable, the easy production of sequence-specific such antisera will facilitate more extended studies of the corresponding antigens for diagnostic and scientific purposes. | |
650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
653 | a Amino Acid Sequence | |
653 | a Animals | |
653 | a Electrophoresis, Polyacrylamide Gel | |
653 | a Immune Sera/analysis | |
653 | a Immunization | |
653 | a Immunohistochemistry | |
653 | a Molecular Sequence Data | |
653 | a Rabbits | |
653 | a Serum Amyloid A Protein/administration & dosage | |
700 | 1 | a Löfberg, Helgeu Lund University,Lunds universitet,Patologi, Malmö,Forskargrupper vid Lunds universitet,Pathology, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)pat-hlo |
700 | 1 | a Thysell, Hansu Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)njur-hth |
700 | 1 | a Ljunggren, Lennartu Lund University4 aut |
700 | 1 | a Olsson, Thomasu Gambro AB4 aut |
700 | 1 | a Skinner, Marthau Boston University4 aut |
700 | 1 | a Shirahama, Tsuranobuu Boston University4 aut |
700 | 1 | a Cohen, Alan Su Boston University4 aut |
710 | 2 | a Avdelningen för klinisk kemi och farmakologib Institutionen för laboratoriemedicin4 org |
773 | 0 | t Scandinavian Journal of Clinical and Laboratory Investigationg 47:6, s. 619-626q 47:6<619-626x 0036-5513 |
856 | 4 | u https://www.tandfonline.com/doi/abs/10.1080/00365518709168478y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/a6411fa9-ac77-4b8a-bf99-261a73ad3818 |
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