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Sökning: onr:"swepub:oai:lup.lub.lu.se:b9982bb4-9c22-471d-9247-43f76bf0aad0" > Ultra-processed foo...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006910naa a2200865 4500
001oai:lup.lub.lu.se:b9982bb4-9c22-471d-9247-43f76bf0aad0
003SwePub
008231204| | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/b9982bb4-9c22-471d-9247-43f76bf0aad02 URI
024a https://doi.org/10.1007/s00394-023-03270-12 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Morales-Berstein, Fernandau University of Bristol4 aut
2451 0a Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study : a mediation analysis
520 a PURPOSE: To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.METHODS: Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the consumption of UPFs and HNC and OAC risk. A mediation analysis was performed to assess the role of body mass index (BMI) and waist-to-hip ratio (WHR) in these associations. In sensitivity analyses, we investigated accidental death as a negative control outcome.RESULTS: During a mean follow-up of 14.13 ± 3.98 years, 910 and 215 participants developed HNC and OAC, respectively. A 10% g/d higher consumption of UPFs was associated with an increased risk of HNC (hazard ratio [HR] = 1.23, 95% confidence interval [CI] 1.14-1.34) and OAC (HR = 1.24, 95% CI 1.05-1.47). WHR mediated 5% (95% CI 3-10%) of the association between the consumption of UPFs and HNC risk, while BMI and WHR, respectively, mediated 13% (95% CI 6-53%) and 15% (95% CI 8-72%) of the association between the consumption of UPFs and OAC risk. UPF consumption was positively associated with accidental death in the negative control analysis.CONCLUSIONS: We reaffirmed that higher UPF consumption is associated with greater risk of HNC and OAC in EPIC. The proportion mediated via adiposity was small. Further research is required to investigate other mechanisms that may be at play (if there is indeed any causal effect of UPF consumption on these cancers).
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
700a Biessy, Carineu International Agency for Research on Cancer, World Health Organization4 aut
700a Viallon, Vivianu International Agency for Research on Cancer, World Health Organization4 aut
700a Goncalves-Soares, Anau University of Bristol4 aut
700a Casagrande, Corinneu International Agency for Research on Cancer, World Health Organization4 aut
700a Hémon, Bertrand4 aut
700a Kliemann, Nathalie4 aut
700a Cairat, Manonu International Agency for Research on Cancer, World Health Organization4 aut
700a Blanco Lopez, Jessica4 aut
700a Al Nahas, Aline4 aut
700a Chang, Kiarau Imperial College London4 aut
700a Vamos, Eszteru Imperial College London4 aut
700a Rauber, Fernandau University of São Paulo4 aut
700a Bertazzi Levy, Renatau University of São Paulo4 aut
700a Barbosa Cunha, Dianau State University of Rio de Janeiro4 aut
700a Jakszyn, Paulau Catalan Institute of Oncology4 aut
700a Ferrari, Pietro4 aut
700a Vineis, Paolou Imperial College London4 aut
700a Masala, Giovannau Institute for Cancer Research, Prevention and Clinical Network (ISPRO)4 aut
700a Catalano, Albertou University of Turin4 aut
700a Sonestedt, Emilyu Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-eso
700a Borné, Yanu Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-boy
700a Katzke, Verenau German Cancer Research Centre4 aut
700a Bajracharya, Rashmitau German Cancer Research Centre4 aut
700a Agnoli, Claudia4 aut
700a Guevara, Marcelau Navarre Public Health Institute (ISPN)4 aut
700a Heath, Aliciau Imperial College London4 aut
700a Radoï, Loredanau University of Paris-Saclay4 aut
700a Mancini, Francescau University of Paris-Saclay4 aut
700a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization4 aut
700a Huerta, José Maríau CIBER Epidemiology and Public Health (CIBERESP)4 aut
700a Sánchez, María-Joséu CIBER Epidemiology and Public Health (CIBERESP)4 aut
700a Tjønneland, Anneu Danish Cancer Society4 aut
700a Kyrø, Cecilieu Danish Cancer Society4 aut
700a Schulze, Matthias Bu German Institute of Human Nutrition4 aut
700a Skeie, Guriu UiT The Arctic University of Norway, Tromsø4 aut
700a Lukic, Markou UiT The Arctic University of Norway, Tromsø4 aut
700a Braaten, Tonjeu UiT The Arctic University of Norway, Tromsø4 aut
700a Gunter, Marc4 aut
700a Millett, Christopheru Imperial College London4 aut
700a Agudo, Antoniou Catalan Institute of Oncology4 aut
700a Brennan, Paulu German Cancer Research Centre4 aut
700a Borges, M Carolinau University of Bristol4 aut
700a Richmond, Rebecca Cu University of Bristol4 aut
700a Richardson, Tom Gu University of Bristol4 aut
700a Davey Smith, Georgeu University of Bristol4 aut
700a Relton, Caroline Lu University of Bristol4 aut
700a Huybrechts, Ingeu International Agency for Research on Cancer, World Health Organization4 aut
710a University of Bristolb International Agency for Research on Cancer, World Health Organization4 org
710a EPIC Network
773t European Journal of Nutritionx 1436-6215
856u http://dx.doi.org/10.1007/s00394-023-03270-1x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/b9982bb4-9c22-471d-9247-43f76bf0aad0
8564 8u https://doi.org/10.1007/s00394-023-03270-1

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