Sökning: onr:"swepub:oai:lup.lub.lu.se:badab1b4-7e62-4d95-b27a-2d75613d1485" > Developmental expre...
Fältnamn | Indikatorer | Metadata |
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000 | 03623naa a2200457 4500 | |
001 | oai:lup.lub.lu.se:badab1b4-7e62-4d95-b27a-2d75613d1485 | |
003 | SwePub | |
008 | 161014s2001 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/badab1b4-7e62-4d95-b27a-2d75613d14852 URI |
024 | 7 | a https://doi.org/10.1016/S0165-3806(01)00221-82 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Johansson, Kjellu Lund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)oft-kjo |
245 | 1 0 | a Developmental expression of DCC in the rat retina |
264 | 1 | c 2001 |
300 | a 6 s. | |
520 | a The protein product of the deleted in colorectal cancer (DCC) gene possesses netrin-binding activity and may be involved in axonal guidance during retinal development. The temporal and spatial expression of DCC was analyzed in developing rat retina by means of immunoblotting and immunohistochemistry as well as by reverse transcription-polymerase chain reaction. Transient DCC protein expression is evident on ganglion cell axons in embryonic and neonatal retina. Double labeling experiments demonstrate DCC immunolabeling on processes that stratify in the inner plexiform layer and are derived from cholinergic amacrine cells. This pattern is maintained during the early postnatal period. DCC immunolabeling in the inner plexiform layer declines with age and is not observed in adult retina. The down-regulation of the DCC protein is confirmed by Western blot analysis. mRNA for DCC is expressed in embryonic, postnatal and adult retina and shows no correlation with the protein down-regulation. We suggest that DCC expression may be correlated with the functional segregation of the inner plexiform layer. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
653 | a Animals | |
653 | a Cell Adhesion Molecules | |
653 | a Choline O-Acetyltransferase | |
653 | a Gene Expression Regulation, Developmental | |
653 | a RNA, Messenger | |
653 | a Rats | |
653 | a Retina | |
653 | a Tumor Suppressor Proteins | |
653 | a Journal Article | |
653 | a Research Support, Non-U.S. Gov't | |
700 | 1 | a Törngren, Marieu Lund University4 aut |
700 | 1 | a Wasselius, Ju Lund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)oft-jws |
700 | 1 | a Månsson, Linau Lund University4 aut |
700 | 1 | a Ehinger, Bu Lund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)oft-beh |
710 | 2 | a Oftalmologi, Lundb Sektion IV4 org |
773 | 0 | t Developmental Brain Researchg 130:1, s. 8-133q 130:1<8-133x 0165-3806 |
856 | 4 | u http://dx.doi.org/10.1016/S0165-3806(01)00221-8y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/badab1b4-7e62-4d95-b27a-2d75613d1485 |
856 | 4 8 | u https://doi.org/10.1016/S0165-3806(01)00221-8 |
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