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Search: onr:"swepub:oai:lup.lub.lu.se:dda22871-d2cb-4baf-b1e7-780706ef6f3f" > Synthesis and confo...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002899naa a2200349 4500
001oai:lup.lub.lu.se:dda22871-d2cb-4baf-b1e7-780706ef6f3f
003SwePub
008160401s2002 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/3373752 URI
024a https://doi.org/10.1016/S0040-4020(02)00170-92 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Maricic, Suzanau Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)orgk1-sm
2451 0a Synthesis and conformational studies of a Leu-enkephalin amide analogue containing a ferrocene substructure
264 1c 2002
520 a Solution phase synthesis of a constrained Leu(5)-enkephalin amide analogue 10 is reported, in which the cyclic ferrocenyl containing subunit 7 was introduced as a mimetic of the tetrapeptide Tyr-Gly-Gly-Phe unit. Temperature dependence of the chemical shift of the amide protons of 10 indicated a hydrogen bond between the same amino acid residues as observed for the natural Leu-enkepalin in the single-bend conformation. The rotational barrier (DeltaG(c)(not equal)=16.8 kcal/mol) of the C-terminal amide group, which was determined by DNMR spectroscopy, and NOESY experiments indicated that the two termini were more distant as compared to the single-bend conformation of natural Leu-enkephalin amide. (C) 2002 Elsevier Science Ltd. All rights reserved.
650 7a NATURVETENSKAPx Kemix Organisk kemi0 (SwePub)104052 hsv//swe
650 7a NATURAL SCIENCESx Chemical Sciencesx Organic Chemistry0 (SwePub)104052 hsv//eng
653 a conformational analysis
653 a ferrocene
653 a cyclic peptide
653 a beta-turn mimetic
700a Berg, Ulfu Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)orgk1-ub
700a Frejd, Torbjörnu Lund University,Lunds universitet,Centrum för analys och syntes,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Centre for Analysis and Synthesis,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)orgk1-tf
710a Centrum för analys och syntesb Kemiska institutionen4 org
773t Tetrahedrong 58:15, s. 3085-3093q 58:15<3085-3093x 0040-4020
856u http://dx.doi.org/10.1016/S0040-4020(02)00170-9y FULLTEXT
8564 8u https://lup.lub.lu.se/record/337375
8564 8u https://doi.org/10.1016/S0040-4020(02)00170-9

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By the author/editor
Maricic, Suzana
Berg, Ulf
Frejd, Torbjörn
About the subject
NATURAL SCIENCES
NATURAL SCIENCES
and Chemical Science ...
and Organic Chemistr ...
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Tetrahedron
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Lund University

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