Sökning: onr:"swepub:oai:lup.lub.lu.se:e07f359f-d7d3-4724-8ab8-b99e8e2b4feb" > The Analgesic Effec...
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001 | oai:lup.lub.lu.se:e07f359f-d7d3-4724-8ab8-b99e8e2b4feb | |
003 | SwePub | |
008 | 180907s2018 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-362493 | |
009 | oai:prod.swepub.kib.ki.se:139017104 | |
009 | oai:prod.swepub.kib.ki.se:140425983 | |
024 | 7 | a https://lup.lub.lu.se/record/e07f359f-d7d3-4724-8ab8-b99e8e2b4feb2 URI |
024 | 7 | a https://doi.org/10.1016/j.jcin.2018.04.0432 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3624932 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1390171042 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1404259832 URI |
040 | a (SwePub)lud (SwePub)uud (SwePub)kid (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Sparv, Davidu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)med-dzt |
245 | 1 0 | a The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction : A Substudy of the DETO2X-AMI Trial |
264 | 1 | b Elsevier BV,c 2018 |
300 | a 8 s. | |
520 | a Objectives: In this substudy of the DETO2X-AMI (An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction) trial, the authors aimed to assess the analgesic effect of moderate-flow oxygen supplementation in patients with suspected acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI) and to study the effect of oxygen supplementation on the use of opiates and sedatives during PCI. Background: Routine oxygen in normoxemic patients with AMI does not provide clinical benefit. However, oxygen may relieve ischemic pain. Methods: Patients were randomly allocated to oxygen or ambient air according to the main study protocol. After PCI, peak level of pain during PCI was measured by the Visual Analogue Scale. The total amount of opiates and sedatives was reported. Results: A total of 622 patients were enrolled: 330 in the oxygen group and 292 in the ambient air group. There was no significant difference in peak level of pain (oxygen 4.0 [1.0 to 6.0] vs. air 3.0 [0.6 to 6.0]; p = 0.37), use of opiates (mg) (oxygen 0.0 [0.0 to 3.0] vs. air 0.0 [0.0 to 3.0]; p = 0.31), or use of sedatives between the groups (median [interquartile range]) (oxygen 2.5 [0.0 to 2.5] vs. air 2.5 [0.0 to 2.5]; p = 0.74). Conclusions: In the present study, the authors did not find any analgesic effect of routine oxygen as compared with ambient air, and no differences in the use of sedatives and opiates during PCI. Our results indicate that moderate-flow oxygen supplementation does not relieve pain in normoxemic patients with suspected AMI undergoing treatment with PCI and should thus not be used for this purpose. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a analgesic effect | |
653 | a oxygen | |
653 | a ST-segment elevation myocardial infarction | |
653 | a analgesic effect | |
700 | 1 | a Hofmann, Robinu Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Karolinska Inst, Sodersjukhuset, Div Cardiol, Dept Clin Sci & Educ, Stockholm, Sweden4 aut |
700 | 1 | a Gunnarsson, Annikau Uppsala University Hospital,Uppsala Univ Hosp, Dept Cardiol, Uppsala, Sweden4 aut |
700 | 1 | a James, Stefan K,d 1964-u Uppsala universitet,Uppsala University,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)stjam367 |
700 | 1 | a Hedberg, Camillau Ryhov County Hospital, Jönköping,Ryhov Hosp, Dept Internal Med, Div Cardiol, Jonkoping, Sweden4 aut |
700 | 1 | a Lauermann, Jörgu Ryhov County Hospital, Jönköping,Ryhov Hosp, Dept Internal Med, Div Cardiol, Jonkoping, Sweden4 aut |
700 | 1 | a Torild, Petronellau Sahlgrenska University Hospital,Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden4 aut |
700 | 1 | a Omerovic, Elmiru Sahlgrenska University Hospital,Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden4 aut |
700 | 1 | a Bergström, Kristinau Gävle Hospital,Gavle Sjukhus, Dept Cardiol, Gavle, Sweden4 aut |
700 | 1 | a Haugen, Espenu Sundsvall Hospital,Sundsvall Reg Hosp, Dept Cardiol, Sundsvall, Sweden4 aut |
700 | 1 | a Bergström, Camillau Danderyd Hospital,Danderyd Hosp, Dept Cardiol, Stockholm, Sweden4 aut |
700 | 1 | a Linder, Rikardu Karolinska Institutet4 aut |
700 | 1 | a Borg, Piau Svensk PCI Varmland AB, Karlstad, Sweden4 aut |
700 | 1 | a Haaga, Urbanu Karlstad Hospital,Cent Hosp Karlstad, Dept Cardiol, Karlstad, Sweden4 aut |
700 | 1 | a Olsson, Anneliu Skåne University Hospital,Skane Univ Hosp, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)an8011ol |
700 | 1 | a Böving, Elinu Stockholm South General Hospital,Soder Sjukhuset, Dept Cardiol, Stockholm, Sweden4 aut |
700 | 1 | a Östlund, Ollieu Uppsala universitet,Uppsala University,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)oos27600 |
700 | 1 | a Rylance, Rebeccau Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)re4842ry |
700 | 1 | a Witt, Nilsu Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Karolinska Inst, Sodersjukhuset, Div Cardiol, Dept Clin Sci & Educ, Stockholm, Sweden4 aut |
700 | 1 | a Erlinge, Davidu Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)kard-der |
700 | 1 | a James, SJ4 aut |
710 | 2 | a Kardiologib Sektion II4 org |
710 | 2 | a DETO2X-SWEDEHEART Investigators |
773 | 0 | t JACC: Cardiovascular Interventionsd : Elsevier BVg 39, s. 546-546q 11:16<1590-1597x 1936-8798x 1876-7605 |
773 | 0 | t EUROPEAN HEART JOURNALd : Elsevier BVg 39, s. 546-546q 39<546-546x 0195-668X |
856 | 4 | u http://dx.doi.org/10.1016/j.jcin.2018.04.043y FULLTEXT |
856 | 4 | u https://doi.org/10.1016/j.jcin.2018.04.043 |
856 | 4 8 | u https://lup.lub.lu.se/record/e07f359f-d7d3-4724-8ab8-b99e8e2b4feb |
856 | 4 8 | u https://doi.org/10.1016/j.jcin.2018.04.043 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-362493 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:139017104 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:140425983 |
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