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Sökning: onr:"swepub:oai:lup.lub.lu.se:f6287eda-9255-4293-99db-517e412afa5e" > Hydrogen peroxide p...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02552naa a2200265 4500 | |
| 001 | oai:lup.lub.lu.se:f6287eda-9255-4293-99db-517e412afa5e | |
| 003 | SwePub | |
| 008 | 160401s1991 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/11059052 URI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Zhang, H4 aut |
| 245 | 1 0 | a Hydrogen peroxide production in ischaemic retina: influence of hyperglycaemia and postischaemic oxygen tension |
| 264 | 1 | c 1991 |
| 520 | a Free radicals have recently been proposed to play a role in the development of diabetic retinopathy. Ischaemia and hyperglycaemia followed by recirculation have been suggested to initiate free radical production in other tissues and the aim of the present study was to examine whether this could also be the case in the retina. The present study showed retinal cell damage, as measured by pycnotic cells, to be more pronounced when ischaemia was combined with hyperglycaemia than when combined with normoglycaemia. As an indication of free radical production, catalase activity was measured, reflecting the production of hydrogen peroxide (H2O2). Small amounts of H2O2 were found to be generated in the normal retina, but did not increase during ischaemia and hyperglycaemia followed by recirculation. It thus seems, as if hyperglycaemia aggravates the harmful effects of ischaemia, but with the methods used, there does not seem to be any increase in free radical production (as measured by H2O2 production) in normal rat retina during ischaemic and hyperglycaemic conditions. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
| 700 | 1 | a Agardh, Elisabetu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)ofta-eag |
| 700 | 1 | a Agardh, Carl-Davidu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)endo-cag |
| 710 | 2 | a Institutionen för kliniska vetenskaper, Malmöb Medicinska fakulteten4 org |
| 773 | 0 | t Diabetes Researchg 16:1, s. 29-35q 16:1<29-35x 0265-5985 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1105905 |
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