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PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
- Kauko, O (author)
- O'Connor, CM (author)
- Kulesskiy, E (author)
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- Sangodkar, J (author)
- Aakula, A (author)
- Izadmehr, S (author)
- Yetukuri, L (author)
- Yadav, B (author)
- Padzik, A (author)
- Laajala, TD (author)
- Haapaniemi, P (author)
- Momeny, M (author)
- Varila, T (author)
- Ohlmeyer, M (author)
- Aittokallio, T (author)
- Wennerberg, K (author)
- Narla, G (author)
- Westermarck, J (author)
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- American Association for the Advancement of Science (AAAS), 2018
- 2018
- English.
- In: Science translational medicine. - : American Association for the Advancement of Science (AAAS). - 1946-6242 .- 1946-6234. ; 10:450
- Journal article (peer-reviewed)
Abstract
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- Pharmacological PP2A activation is a druggable approach to overcome MEK inhibitor resistance.
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- art (subject category)
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- Kauko, O
- O'Connor, CM
- Kulesskiy, E
- Sangodkar, J
- Aakula, A
- Izadmehr, S
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- Yetukuri, L
- Yadav, B
- Padzik, A
- Laajala, TD
- Haapaniemi, P
- Momeny, M
- Varila, T
- Ohlmeyer, M
- Aittokallio, T
- Wennerberg, K
- Narla, G
- Westermarck, J
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- Karolinska Institutet
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