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Health-related qual...
Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms.
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- Hammerlid, Eva, 1957 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
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- Taft, Charles, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin,Institute of Internal Medicine
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(creator_code:org_t)
- 2001-01-15
- 2001
- Engelska.
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Ingår i: British journal of cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 84:2, s. 149-56
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https://www.nature.c...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- To examine the health-related quality of life (HRQL) in long-term head and neck (H&N) cancer survivors compared with general population norms. HRQL was assessed with three standardized questionnaires: the SF-36 Health Survey (Short Form 36) and the EORTC QLQ-C30 and QLQ-H&N35 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, -Core 30 and -Head and Neck 35 cancer module). Altogether 135 H&N cancer patients (mean age 62 years, 31% females) of 151 survivors (89% acceptance) from a longitudinal HRQL study (n = 232) were included 3 years after diagnosis. The H&N cancer patients' SF-36 scores did not differ significantly from those of an age- and sex-matched sample (n = 871) from the Swedish normative population, except on the role-physical functioning scale. On the other hand, treatment-related side-effects and disease-specific problems (e.g., swallowing, local pain and dry mouth) measured by the H&N cancer module were, with few exceptions, significantly worse than norm values. Gender comparisons revealed that female H&N cancer patients generally scored better than the norms on both the SF-36 and the EORTC QLQ-C30, while the male patients scored significantly worse on most SF-36 scales. Patients > or =65 years more often scored worse than the norm than did patients <65. Clinically relevant differences were found on the majority of SF-36 scales in comparison of tumour sites, however, comparisons of patients with small (stage I+II) versus advanced (stage III+IV) tumours revealed few differences. Three years after diagnosis H&N cancer patients still suffer significant functional limitations/problems related to their disease and its treatment but these problems do not generally affect their overall HRQL. Tumour stage no longer differentiates HRQL at 3 years, however, factors related to the patients' age, gender and location of the tumour appear to have bearing on their reported health status.
Nyckelord
- Adolescent
- Adult
- Aged
- Aged
- 80 and over
- Cough
- etiology
- Female
- Head and Neck Neoplasms
- complications
- psychology
- Health Surveys
- Humans
- Laryngeal Neoplasms
- complications
- psychology
- Male
- Middle Aged
- Mouth Neoplasms
- complications
- psychology
- Neoplasm Staging
- Norway
- Pain
- etiology
- Pharyngeal Neoplasms
- complications
- psychology
- Population Surveillance
- Quality of Life
- Survivors
- psychology
- statistics & numerical data
- Sweden
- Tooth Diseases
- etiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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