Pulmonary dysfunction, smoking, socioeconomic status and the risk of developing rheumatoid arthritis.

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Sökning: (WFRF:(Bergström Göran)) srt2:(2010-2011) > Pulmonary dysfuncti...

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Fältnamn	Indikatorer	Metadata
000		04302naa a2200361 4500
001		oai:lup.lub.lu.se:c2332346-7f9b-4a69-9956-5ddc3b187b14
003		SwePub
008		160404s2011 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://lup.lub.lu.se/record/21507712 URI
024	7	a https://doi.org/10.1093/rheumatology/ker2582 DOI
040		a (SwePub)lu
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Bergström, Ulfu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-ubs
245	1 0	a Pulmonary dysfunction, smoking, socioeconomic status and the risk of developing rheumatoid arthritis.
264		c 2011-08-22
264	1	b Oxford University Press (OUP),c 2011
520		a Objectives. Environmental risk factors are of potential interest for both prevention and treatment of RA. The purpose of this study was to examine the effect of pulmonary function, smoking and socio-economic status on the future risk of RA. Methods. Between 1974 and 1992, 22 444 men and 10 902 women were included in the Malmö Preventive Medicine Program (MPMP). Pulmonary function was assessed by a standard screening spirometry. Chronic obstructive pulmonary disease (COPD) and restrictive pulmonary dysfunction were defined based on pulmonary function tests. Individuals who developed RA were identified by linking the MPMP database to national and local RA registers. The patients were classified according to the 1987 ACR criteria for RA. Four matched controls for every case were selected. Results. We identified 290 cases of incident RA (151 men/139 women; mean age at diagnosis 60 years). The median time from inclusion to diagnosis was 12 years. Forced vital capacity and forced expiratory volume within 1 s values were similar in cases and controls, overall and also in separate analysis of those screened ≤8 years before diagnosis. There was no association between COPD or restrictive pulmonary dysfunction and subsequent development of RA. Current smoking was a strong predictor for RA [odds ratio (OR) 1.79; 95% CI 1.32, 2.42]. Blue-collar workers had an increased risk of RA (OR 1.54; 95% CI 1.12, 2.10), independent of smoking. Conclusion. Pulmonary dysfunction did not predict RA, but smoking and low socio-economic status were independent risk factors for RA. Other effects of smoking may be important for RA susceptibility
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
700	1	a Jacobsson, Lennartu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)orto-lja
700	1	a Nilsson, Jan-Åkeu Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups4 aut0 (Swepub:lu)med-jnn
700	1	a Berglund, Göranu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-gbe
700	1	a Turesson, Carlu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-ctn
710	2	a Internmedicin - epidemiologib Forskargrupper vid Lunds universitet4 org
773	0	t Rheumatology (Oxford, England)d : Oxford University Press (OUP)g 50, s. 2005-2013q 50<2005-2013x 1462-0332x 1462-0324
856	4	u http://www.ncbi.nlm.nih.gov/pubmed/21859698?dopt=Abstracty FULLTEXT
856	4	u http://dx.doi.org/10.1093/rheumatology/ker258y FULLTEXT
856	4	u https://academic.oup.com/rheumatology/article-pdf/50/11/2005/5052577/ker258.pdf
856	4 8	u https://lup.lub.lu.se/record/2150771
856	4 8	u https://doi.org/10.1093/rheumatology/ker258

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Av författaren/redakt...: Bergström, Ulf; Jacobsson, Lenna ...; Nilsson, Jan-Åke; Berglund, Göran; Turesson, Carl

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Reumatologi och ...

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