Protein gene product 9.5-immunoreactive nerve fibres and cells in human skin

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Sökning: L773:0302 766X OR L773:1432 0878 > (1990-1994) > Protein gene produc...

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Fältnamn	Indikatorer	Metadata
000		03261naa a2200325 4500
001		oai:DiVA.org:oru-78455
003		SwePub
008		191219s1990 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-784552 URI
024	7	a https://doi.org/10.1007/bf003294352 DOI
040		a (SwePub)oru
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Wang, Lu Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden4 aut
245	1 0	a Protein gene product 9.5-immunoreactive nerve fibres and cells in human skin
264	1	b Springer,c 1990
338		a print2 rdacarrier
520		a Sections of human skin were processed according to the indirect immunofluorescence technique with a rabbit antiserum against human protein gene product 9.5 (PGP 9.5). Immunoreactivity was detected in intraepidermal and dermal nerve fibres and cells. The intraepidermal nerves were varicose or smooth with different diameters, running as single processes or branched, straight or bent, projecting in various directions and terminating in the stratum basale, spinosum or granulosum. The density of the intraepidermal nerves varied between the different skin areas investigated. PGP 9.5-containing axons of the lower dermis were found in large bundles. They separated into smaller axon bundles within the upper dermis, entering this portion of the skin perpendicular to the surface. Then they branched into fibres mainly arranged parallel to the epidermal-dermal junctional zone. However, the fibres en route to the epidermis traversed the upper dermis more or less perpendicularly. Furthermore, immunoreactive dermal nerve fibres were found in the Meissner corpuscles, the arrector pili muscles, hair follicles, around the eccrine and apocrine sweat glands and around certain blood vessels. Such fibres were also observed around most subcutaneous blood vessels, sometimes heavily innervating these structures. Numerous weakly-to-strongly PGP 9.5-immunoreactive cells were found both in the epidermis and in the dermis.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng
700	1	a Hilliges, Mu Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden4 aut
700	1	a Jernberg, Tu Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden4 aut
700	1	a Wiegleb Edström, Desirée,d 1959-u Department of Dermatology, Karolinska Hospital, Stockholm, Sweden4 aut0 (Swepub:oru)dwm
700	1	a Johansson, Ou Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden4 aut
710	2	a Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Swedenb Department of Dermatology, Karolinska Hospital, Stockholm, Sweden4 org
773	0	t Cell and Tissue Researchd : Springerg 261:1, s. 25-33q 261:1<25-33x 0302-766Xx 1432-0878
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-78455
856	4 8	u https://doi.org/10.1007/bf00329435

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Av författaren/redakt...: Wang, L; Hilliges, M; Jernberg, T; Wiegleb Edström, ...; Johansson, O

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Dermatologi och ...

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Av lärosätet: Örebro universitet

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