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Sökning: WFRF:(Andrys Ctirad) > Presence of Chlamyd...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004374naa a2200481 4500
001oai:gup.ub.gu.se/282543
003SwePub
008240528s2021 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/2825432 URI
0247 a https://doi.org/10.1080/14767058.2019.16406762 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Kacerovsky, Marian4 aut
2451 0a Presence of Chlamydia trachomatis DNA in the amniotic fluid in women with preterm prelabor rupture of membranes.
264 c 2019-07-15
264 1b Informa UK Limited,c 2021
520 a Objective: The primary aim of this study was to assess the rate and load of amniotic fluid Chlamydia trachomatis DNA and their associations with intra-amniotic infection and intra-uterine inflammatory complications in women with preterm prelabor rupture of membranes (PPROM). The secondary aim was to assess the short-term morbidity of newborns from PPROM pregnancies complicated by amniotic fluid C. trachomatis DNA. Methods: A retrospective study of 788 women with singleton pregnancies complicated by PPROM between 24+0 and 36+6weeks of gestation was performed. Transabdominal amniocenteses were performed at the time of admission. C. trachomatis DNA in the amniotic fluid was assessed by real-time polymerase chain reaction using a commercial AmpliSens® C. trachomatis/Ureaplasma/Mycoplasma hominis-FRT kit, and the level of Ct DNA was quantified. Results: Amniotic fluid C. trachomatis DNA complicated 2% (16/788) of the PPROM pregnancies and was present in very low loads (median 57 copies DNA/mL). In addition to amniotic fluid C. trachomatis DNA, other bacteria were detected in 62% (10/16) of the C. trachomatis DNA-complicated PPROM pregnancies. Amniotic fluid C. trachomatis DNA was associated with intra-amniotic infection, histologic chorioamnionitis (HCA), and funisitis in 31%, 47%, and 33%, respectively. The presence of C. trachomatis DNA accompanied by Ureaplasma species in the amniotic fluid was associated with a higher rate of HCA than the presence of amniotic fluid C. trachomatis DNA alone. The composite neonatal morbidity in newborns from PPROM pregnancies with amniotic fluid C. trachomatis DNA was 31%. Conclusion: The presence of C. trachomatis DNA in the amniotic fluid is a relatively rare condition in PPROM. Amniotic fluid C. trachomatis DNA in PPROM is not related to intensive intra-amniotic and intr-auterine inflammatory responses or adverse short-term neonatal outcomes.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng
653 a Amniotic fluid
653 a intra-amniotic inflammation
653 a intra-cellular bacteria
653 a preterm delivery
7001 a Romero, Roberto4 aut
7001 a Pliskova, Lenka4 aut
7001 a Bolehovska, Radka4 aut
7001 a Hornychova, Helena4 aut
7001 a Matejkova, Adela4 aut
7001 a Vosmikova, Hana4 aut
7001 a Andrys, Ctirad4 aut
7001 a Kolackova, Martina4 aut
7001 a Laudański, Piotr4 aut
7001 a Pelantova, Vera4 aut
7001 a Jacobsson, Bo,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology4 aut0 (Swepub:gu)xjacbo
7001 a Musilova, Ivana4 aut
7102 a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi4 org
7730 t The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetriciansd : Informa UK Limitedg 34:10, s. 1586-1597q 34:10<1586-1597x 1476-4954
7730 t The Journal of Maternal-Fetal & Neonatal Medicined : Informa UK Limitedg 34:10, s. 1586-1597q 34:10<1586-1597x 1476-7058
8564 8u https://gup.ub.gu.se/publication/282543
8564 8u https://doi.org/10.1080/14767058.2019.1640676

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