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Quantitative assess...
Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio)
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- Peddinghaus, Sabrina (författare)
- Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Aachen, Germany
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- Brinkmann, Markus (författare)
- Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Aachen, Germany
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- Bluhm, Kerstin (författare)
- Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Aachen, Germany
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- Sagner, Anne (författare)
- Department of Environmental Biotechnology, Water Technology Center (TZW), Karlsruhe, Germany
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- Hinger, Gunnar (författare)
- Aquatic Ecology and Toxicology, Centre for Organismal Studies, University of Heidelberg, Heidelberg, Germany
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- Braunbeck, Thomas (författare)
- Aquatic Ecology and Toxicology, Centre for Organismal Studies, University of Heidelberg, Heidelberg, Germany
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- Eisenträger, Adolf (författare)
- Dept. IV 2: Pharmaceuticals, Chemicals, Experimental Studies, Federal Environment Agency, Dessau, Germany; Institute of Hygiene and Environmental, Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany
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- Thiem, Andreas (författare)
- Department of Environmental Biotechnology, Water Technology Center (TZW), Karlsruhe, Germany
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- Hollert, Henner (författare)
- Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Aachen, Germany
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- Keiter, Steffen, 1971- (författare)
- Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Aachen, Germany,MTM
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(creator_code:org_t)
- Oxford, United Kingdom : Springer, 2012
- 2012
- Engelska.
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Ingår i: Reproductive Toxicology. - Oxford, United Kingdom : Springer. - 0890-6238 .- 1873-1708. ; 33, s. 224-232
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Heterocyclic aromatic compounds (NSO-HET) have frequently been detected in the environment. Several studies have concluded that NSO-HET pose a threat to organisms in waters, sediments and soils. However, few publications are available assessing the ecotoxicology of NSO-HET. The present study aims toassess the embryo toxicity of heterocycles using Danio rerio. A combination of the Fish Embryo Toxicity Test and analytical quantification should aid to determine the hazard potential. Changes of the total concentrations due to sorption or volatility were quantified by GC/MS. Loss of compounds during the testwas observed primarily for volatile or hydrophobic NSO-HET. The LC50 calculated with nominal concentrations underestimates the toxicity by a factor up to 16 (2 h), demonstrating that a chemical analysis for comparing nominal and measured concentrations is essential for such investigations.
Ämnesord
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Nyckelord
- Heterocyclic aromatic compounds
- NSO-HET
- Zebrafish
- Embryo toxicity
- Fish embryo toxicity test
- Enviromental Science
- Miljövetenskap
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Peddinghaus, Sab ...
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Brinkmann, Marku ...
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Bluhm, Kerstin
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Sagner, Anne
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Hinger, Gunnar
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Braunbeck, Thoma ...
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visa fler...
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Eisenträger, Ado ...
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Thiem, Andreas
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Hollert, Henner
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Keiter, Steffen, ...
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Reproductive Tox ...
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Örebro universitet