Glycemic and risk factor control in type 1 diabetes: results from 13,612 patients in a national diabetes register

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Fältnamn	Indikatorer	Metadata
000		04781naa a2200613 4500
001		oai:gup.ub.gu.se/49464
003		SwePub
008		240528s2007 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:uu-10354
009		oai:lup.lub.lu.se:6649df99-4e31-4cc6-99ac-e1f661a877d2
024	7	a https://gup.ub.gu.se/publication/494642 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-103542 URI
024	7	a https://doi.org/10.2337/dc06-14062 DOI
024	7	a https://lup.lub.lu.se/record/6701732 URI
040		a (SwePub)gud (SwePub)uud (SwePub)lu
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Eeg-Olofsson, Katarina,d 1968u Uppsala universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Institutionen för kvinnors och barns hälsa4 aut0 (Swepub:uu)kaede030
245	1 0	a Glycemic and risk factor control in type 1 diabetes: results from 13,612 patients in a national diabetes register
264	1	b American Diabetes Association,c 2007
520		a OBJECTIVE: This study was designed to investigate the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. RESEARCH DESIGN AND METHODS: The Swedish National Diabetes Register was initiated in 1996 as a tool for quality assurance in diabetes care. A1C levels, treatment, and risk factors were analyzed in two cross-sectional samples of 9,424 patients in 1997 and 13,612 patients in 2004 and in a smaller longitudinal sample from 1997 to 2004. RESULTS: Mean A1C decreased from 8.2 +/- 1.3% in 1997 to 8.0 +/- 1.2% in 2004 (P < 0.001). The proportion of patients reaching A1C <7.0% increased from 17.4 to 21.2% in 2004. A slow but significant improvement in blood pressure levels was seen, but only 61.3% reached the blood pressure goal of <130/80 mmHg in 2004. Lipid control improved, and the use of lipid-lowering drugs increased. Among patients treated with lipid-lowering agents, 38% reached the goal of total cholesterol <4.5 mmol/l, and 48% reached the goal of LDL cholesterol <2.5 mmol/l. Successful long-term glycemic and blood pressure control were both independently predicted by low BMI and the absence of microalbuminuria in 1997. CONCLUSIONS: In this large cohort of type 1 diabetic patients, there was a slow improvement in glycemic and risk factor control from 1997 to 2004, although the gap between the clinical results and current Swedish and American treatment goals is still unsatisfactory. It is crucial that additional measures be taken to improve risk factor control in type 1 diabetic patients.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653		a Adult
653		a Blood Glucose/*metabolism
653		a Blood Pressure
653		a Diabetes Mellitus
653		a Type 1/blood/epidemiology
653		a Female
653		a Hemoglobin A
653		a Glycosylated/*metabolism
653		a Humans
653		a Male
653		a Middle Aged
653		a Registries
653		a Regression Analysis
653		a Risk Factors
653		a Sweden/epidemiology
653		a Immunopathology
653		a MEDICINE
700	1	a Cederholm, Janu Uppsala universitet,Allmänmedicin och klinisk epidemiologi4 aut0 (Swepub:uu)janceder
700	1	a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni
700	1	a Gudbjörnsdottir, Soffia,d 1962u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xgudso
700	1	a Eliasson, Björn,d 1959u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xelibj
710	2	a Göteborgs universitetb Institutionen för medicin4 org
773	0	t Diabetes Cared : American Diabetes Associationg 30:3, s. 496-502q 30:3<496-502x 1935-5548x 0149-5992
856	4	u https://care.diabetesjournals.org/content/diacare/30/3/496.full.pdf
856	4	u http://dx.doi.org/10.2337/dc06-1406x freey FULLTEXT
856	4 8	u https://gup.ub.gu.se/publication/49464
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-10354
856	4 8	u https://doi.org/10.2337/dc06-1406
856	4 8	u https://lup.lub.lu.se/record/670173

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Av författaren/redakt...: Eeg-Olofsson, Ka ...; Cederholm, Jan; Nilsson, Peter; Gudbjörnsdottir, ...; Eliasson, Björn, ...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Endokrinologi oc ...

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Av lärosätet: Göteborgs universitet; Uppsala universitet; Lunds universitet

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