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FältnamnIndikatorerMetadata
00009681naa a2200877 4500
001oai:DiVA.org:uu-514076
003SwePub
008231013s2023 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-212840
009oai:DiVA.org:liu-198385
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0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5140762 URI
0247 a https://doi.org/10.1016/j.ejvs.2023.06.0192 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2128402 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1983852 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1538188282 URI
0247 a https://lup.lub.lu.se/record/4338375c-a6d6-453f-9a99-18941c7c5e372 URI
040 a (SwePub)uud (SwePub)umud (SwePub)liud (SwePub)kid (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Gavali, Hamidu Uppsala University,Uppsala universitet,Kärlkirurgi,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden4 aut0 (Swepub:uu)hamga922
2451 0a Semi-Conservative Treatment Versus Radical Surgery in Abdominal Aortic Graft and Endograft Infections
264 1b Elsevier,c 2023
338 a electronic2 rdacarrier
520 a Objective: Abdominal aortic graft and endograft infections (AGIs) are rare complications following aortic surgery. Radical surgery (RS) with resection of the infected graft and reconstruction with extra-anatomical bypass or in situ reconstruction is the preferred therapy. For patients unfit for RS, a semi-conservative (SC), graft preserving strategy is possible. This paper aimed to compare survival and infection outcomes between RS and SC treatment for AGI in a nationwide cohort.Methods: Patients with abdominal AGI related surgery in Sweden between January 1995 and May 2017 were identified. The Management of Aortic Graft Infection Collaboration (MAGIC) criteria were used for the definition of AGI. Multivariable regression was performed to identify factors associated with mortality.Results: One hundred and sixty-nine patients with surgically treated abdominal AGI were identified, comprising 43 SC (14 endografts; 53% with a graft enteric fistula [GEF] in total) and 126 RS (26 endografts; 50% with a GEF in total). The SC cohort was older and had a higher frequency of cardiac comorbidities. There was a non-significant trend towards lower Kaplan -Meier estimated five year survival for SC vs. RS (30.2% vs. 48.4%; p = .066). A non-significant trend was identified towards worse Kaplan -Meier estimated five year survival for SC patients with a GEF vs. without a GEF (21.7% vs. 40.1%; p = .097). There were significantly more recurrent graft infections comparing SC with RS (45.4% vs. 19.3%; p < .001). In a Cox regression model adjusting for confounders, there was no difference in five year survival comparing SC vs. RS (HR 1.0, 95% CI 0.6 -1.5).Conclusion: In this national AGI cohort, there was no mortality difference comparing SC and RS for AGI when adjusting for comorbidities. Presence of GEF probably negatively impacts survival outcomes of SC patients. Rates of recurrent infection remain high for SC treated patients.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a Aortic graft infection
653 a Multicentre
653 a Nationwide
653 a Radical surgery
653 a Semi-conservative
653 a Aortic graft infection
653 a Multicentre
653 a Nationwide
653 a Radical surgery
653 a Semi-conservative
7001 a Mani, Kevin,d 1975-u Uppsala University,Uppsala universitet,Kärlkirurgi,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden4 aut0 (Swepub:uu)kevma940
7001 a Furebring, Miau Uppsala University,Uppsala universitet,Infektionsmedicin,Department of Medical Sciences, Section of Infectious Diseases, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden4 aut0 (Swepub:uu)miafureb
7001 a Olsson, Karl Wilhelm,d 1985-u Uppsala University,Uppsala universitet,Kärlkirurgi,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden4 aut0 (Swepub:uu)karol118
7001 a Lindström, Davidu Uppsala University,Uppsala universitet,Kärlkirurgi,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden4 aut0 (Swepub:uu)davli314
7001 a Sörelius, Karlu Rigshospitalet, Dept Vasc Surg, Copenhagen, Denmark.,Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark; and Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,Copenhagen University Hospital4 aut
7001 a Sigvant, Birgittau Uppsala University,Uppsala universitet,Kärlkirurgi,Karlstad Cent Hosp, Dept Vasc Surg, Karlstad, Sweden.,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden; Department of Vascular Surgery, Karlstad Central Hospital, Karlstad, Sweden,Uppsala Univ, Sweden; Karlstad Cent Hosp, Sweden4 aut0 (Swepub:uu)birsi511
7001 a Torstensson, Gustavu Helsingborg Hosp, Dept Surg, Helsingborg, Sweden.,Department of Surgery, Helsingborg Regional Hospital, Helsingborg, Sweden4 aut0 (Swepub:lu)gu8201to
7001 a Andersson, Manneu Linköping University,Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Cty Hosp Ryhov, Sweden,Ryhov County Hospital, Jönköping4 aut0 (Swepub:liu)manan92
7001 a Forssell, Claesu Linköping Univ Hosp, Dept Cardiovasc Surg, Div Vasc Surg, Linköping, Sweden.,Department of Cardiovascular Surgery, Division of Vascular Surgery, Linköping University Hospital, Linköping, Sweden,Region Östergötland, Thorax-kärlkliniken i Östergötland4 aut0 (Swepub:liu)n/a
7001 a Åstrand, Håkanu Cty Hosp Ryhov, Dept Surg, Jönköping, Sweden.,Department of Surgery, County Hospital Ryhov, Ryhov, Jönköping County, Sweden4 aut
7001 a Lundström, Tobiasu Eskilstuna Hosp, Dept Surg & Urol, Eskilstuna, Sweden.,Department of Surgery and Urology, Eskilstuna Hospital, Eskilstuna, Sweden4 aut
7001 a Khan, Shahzadu Lund Univ, Malmö Univ Hosp, Dept Surg, Malmö, Sweden.,Department of Surgery, Malmö University Hospital, Lund University, Malmö, Sweden,Skåne University Hospital4 aut
7001 a Sonesson, Björnu Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kir-bso
7001 a Stackelberg, Ottou Karolinska Institute4 aut
7001 a Gillgren, Peteru Karolinska Institute,Karolinska Institutet,Stockholm South General Hospital4 aut
7001 a Isaksson, Jonu Umeå University,Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.4 aut0 (Swepub:umu)jois0027
7001 a Kragsterman, Björnu Uppsala University,Uppsala universitet,Kärlkirurgi,Västerås Hosp, Dept Surg, Västerås, Sweden.,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden; Department of Surgery, Västerås Central Hospital, Västerås, Sweden,Uppsala Univ, Sweden; Vasteras Hosp, Sweden,Västmanland Hospital4 aut0 (Swepub:uu)bjkra123
7001 a Gidlund, Khatereh Djavaniu Örebro University4 aut
7001 a Horer, Talu Örebro University4 aut
7001 a Sadeghi, Mitrau Örebro University4 aut
7001 a Wanhainen, Andersu Uppsala University,Umeå University,Uppsala universitet,Kärlkirurgi,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden; Umea Univ, Sweden4 aut0 (Swepub:uu)anwan103
7102 a Uppsala universitetb Kärlkirurgi4 org
7730 t European Journal of Vascular and Endovascular Surgeryd : Elsevierg 66:3, s. 397-406q 66:3<397-406x 1078-5884x 1532-2165
8564 u https://doi.org/10.1016/j.ejvs.2023.06.019y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1804783/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://umu.diva-portal.org/smash/get/diva2:1787854/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print
8564 u https://liu.diva-portal.org/smash/get/diva2:1803777/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u http://dx.doi.org/10.1016/j.ejvs.2023.06.019x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-514076
8564 8u https://doi.org/10.1016/j.ejvs.2023.06.019
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-212840
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-198385
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:153818828
8564 8u https://lup.lub.lu.se/record/4338375c-a6d6-453f-9a99-18941c7c5e37

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