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Challenges and Oppo...
Challenges and Opportunities With Routinely Collected Data on the Utilization of Cancer Medicines. Perspectives From Health Authority Personnel Across 18 European Countries
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- Pisana, Alice (författare)
- Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden.
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- Wettermark, Björn (författare)
- Uppsala universitet,Institutionen för farmaci,Vilnius Univ, Fac Med, Vilnius, Lithuania.
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- Kurdi, Amanj (författare)
- Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow City, Scotland.;Hawler Med Univ, Coll Pharm, Dept Pharmacol & Toxicol, Erbil, Iraq.;Sefako Makgatho Hlth Sci Univ, Sch Pharm, Div Publ Hlth Pharm & Management, Pretoria, South Africa.
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- Tubic, Biljana (författare)
- Univ Banja Luka, Fac Med, Dept Pharm, Banja Luka, Bosnia & Herceg.
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- Pontes, Caridad (författare)
- Catalan Hlth Serv, Barcelona, Spain.;Univ Autonoma Barcelona, Dept Pharmacol Therapeut & Toxicol, Barcelona, Spain.
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- Zara, Corinne (författare)
- Catalan Hlth Serv, Barcelona, Spain.
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- Van Ganse, Eric (författare)
- RESHAPE, INSERM U1290, Lyon, France.;Claude Bernard Univ Lyon 1, Lyon, France.;Croix Rousse Univ Hosp, Asthma Self Care Training Unit, Resp Med, Lyon, France.
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- Petrova, Guenka (författare)
- PELyon, PharmacoEpidemiol Lyon, Lyon, France.
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- Mardare, Ileana (författare)
- Carol Davila Univ Med & Pharm, Fac Med, Publ Hlth & Management Dept, Bucharest, Romania.
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- Fürst, Jurij (författare)
- Hlth Insurance Inst, Ljubljana, Slovenia.
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- Roig-Izquierdo, Marta (författare)
- Catalan Hlth Serv, Barcelona, Spain.
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- Melien, Oyvind (författare)
- Oslo Univ Hosp, Head Sect Drug Therapeut & Safety, Oslo, Norway.;Oslo Univ Hosp, Head Natl Ctr Drug Shortage Specialist Hlth Care, Dept Pharmacol, Oslo, Norway.
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- Bonanno, Patricia Vella (författare)
- Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Div Pharmacoepidemiol, Glasgow City, Scotland.;Univ Malta, Fac Hlth Sci, Dept Hlth Syst Management & Leadership, Msida, Malta.
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- Banzi, Rita (författare)
- Ist Ric Farmacolog Mario Negri IRCCS, Ctr Hlth Regulatory Pol, Milan, Italy.
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- Markovic-Pekovic, Vanda (författare)
- Univ Banja Luka, Fac Med, Dept Social Pharm, Banja Luka, Bosnia & Herceg.
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- Mitkova, Zornitsa (författare)
- PELyon, PharmacoEpidemiol Lyon, Lyon, France.
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- Godman, Brian (författare)
- Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Glasgow City, Scotland.;Sefako Makgatho Hlth Sci Univ, Sch Pharm, Div Publ Hlth Pharm & Management, Pretoria, South Africa.
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Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden Institutionen för farmaci (creator_code:org_t)
- 2022-06-16
- 2022
- Engelska.
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Ingår i: Frontiers in Pharmacology. - : Frontiers Media S.A.. - 1663-9812. ; 13
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Rising expenditure for new cancer medicines is accelerating concerns that their costs will become unsustainable for universal healthcare access. Moreover, early market access of new oncology medicines lacking appropriate clinical evaluation generates uncertainty over their cost-effectiveness and increases expenditure for unknown health gain. Patient-level data can complement clinical trials and generate better evidence on the effectiveness, safety and outcomes of these new medicines in routine care. This can support policy decisions including funding. Consequently, there is a need for improving datasets for establishing real-world outcomes of newly launched oncology medicines.Aim: To outline the types of available datasets for collecting patient-level data for oncology among different European countries. Additionally, to highlight concerns regarding the use and availability of such data from a health authority perspective as well as possibilities for cross-national collaboration to improve data collection and inform decision-making.Methods: A mixed methods approach was undertaken through a cross-sectional questionnaire followed-up by a focus group discussion. Participants were selected by purposive sampling to represent stakeholders across different European countries and healthcare settings. Descriptive statistics were used to analyze quantifiable questions, whilst content analysis was employed for open-ended questions.Results: 25 respondents across 18 European countries provided their insights on the types of datasets collecting oncology data, including hospital records, cancer, prescription and medicine registers. The most available is expenditure data whilst data concerning effectiveness, safety and outcomes is less available, and there are concerns with data validity. A major constraint to data collection is the lack of comprehensive registries and limited data on effectiveness, safety and outcomes of new medicines. Data ownership limits data accessibility as well as possibilities for linkage, and data collection is time-consuming, necessitating dedicated staff and better systems to facilitate the process. Cross-national collaboration is challenging but the engagement of multiple stakeholders is a key step to reach common goals through research.Conclusion: This study acts as a starting point for future research on patient-level databases for oncology across Europe. Future recommendations will require continued engagement in research, building on current initiatives and involving multiple stakeholders to establish guidelines and commitments for transparency and data sharing.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
Nyckelord
- new cancer medicines
- patient-level datasets
- pricing and reimbursement
- funding concerns
- pharmaceutical policy
- cross-national collaboration
- european countries
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- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Pisana, Alice
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Wettermark, Björ ...
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Kurdi, Amanj
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Tubic, Biljana
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Pontes, Caridad
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Zara, Corinne
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visa fler...
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Van Ganse, Eric
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Petrova, Guenka
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Mardare, Ileana
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Fürst, Jurij
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Roig-Izquierdo, ...
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Melien, Oyvind
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Bonanno, Patrici ...
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Banzi, Rita
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Markovic-Pekovic ...
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Mitkova, Zornits ...
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Godman, Brian
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Uppsala universitet
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Karolinska Institutet