EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer – An International Collaborative Multistakeholder Effort: Under the Auspices of the EAU-ESMO Guidelines Committees

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Fältnamn	Indikatorer	Metadata
000		09629naa a2201849 4500
001		oai:DiVA.org:umu-166179
003		SwePub
008		191213s2020 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:142749555
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1661792 URI
024	7	a https://doi.org/10.1016/j.eururo.2019.09.0352 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1427495552 URI
040		a (SwePub)umud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Witjes, J. Alfred4 aut
245	1 0	a EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer – An International Collaborative Multistakeholder Effort :b Under the Auspices of the EAU-ESMO Guidelines Committees
264	1	b Elsevier,c 2020
338		a print2 rdacarrier
500		a Errata: Witjes JA, Babjuk M, Bellmunt J, et al. Corrigendum to 'EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer-An International Collaborative Multistakeholder Effort Under the Auspices of the EAU-ESMO Guidelines Committees' [European Urology 77 (2020) 223-250]. Eur Urol. 2020;78(1):e48-e50. doi:10.1016/j.eururo.2020.03.017
520		a BACKGROUND: Although guidelines exist for advanced and variant bladder cancer management, evidence is limited/conflicting in some areas and the optimal approach remains controversial.OBJECTIVE: To bring together a large multidisciplinary group of experts to develop consensus statements on controversial topics in bladder cancer management.DESIGN: A steering committee compiled proposed statements regarding advanced and variant bladder cancer management which were assessed by 113 experts in a Delphi survey. Statements not reaching consensus were reviewed; those prioritised were revised by a panel of 45 experts prior to voting during a consensus conference.SETTING: Online Delphi survey and consensus conference.PARTICIPANTS: The European Association of Urology (EAU), the European Society for Medical Oncology (ESMO), experts in bladder cancer management.OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Statements were ranked by experts according to their level of agreement: 1-3 (disagree), 4-6 (equivocal), and 7-9 (agree). A priori (level 1) consensus was defined as ≥70% agreement and ≤15% disagreement, or vice versa. In the Delphi survey, a second analysis was restricted to stakeholder group(s) considered to have adequate expertise relating to each statement (to achieve level 2 consensus).RESULTS AND LIMITATIONS: Overall, 116 statements were included in the Delphi survey. Of these statements, 33 (28%) achieved level 1 consensus and 49 (42%) achieved level 1 or 2 consensus. At the consensus conference, 22 of 27 (81%) statements achieved consensus. These consensus statements provide further guidance across a broad range of topics, including the management of variant histologies, the role/limitations of prognostic biomarkers in clinical decision making, bladder preservation strategies, modern radiotherapy techniques, the management of oligometastatic disease, and the evolving role of checkpoint inhibitor therapy in metastatic disease.CONCLUSIONS: These consensus statements provide further guidance on controversial topics in advanced and variant bladder cancer management until a time when further evidence is available to guide our approach.PATIENT SUMMARY: This report summarises findings from an international, multistakeholder project organised by the EAU and ESMO. In this project, a steering committee identified areas of bladder cancer management where there is currently no good-quality evidence to guide treatment decisions. From this, they developed a series of proposed statements, 71 of which achieved consensus by a large group of experts in the field of bladder cancer. It is anticipated that these statements will provide further guidance to health care professionals and could help improve patient outcomes until a time when good-quality evidence is available.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
653		a Bladder cancer
653		a Consensus
653		a Delphi
653		a Diagnosis
653		a Follow-up
653		a Treatment
700	1	a Babjuk, Marek4 aut
700	1	a Bellmunt, Joaquim4 aut
700	1	a Bruins, H. Maxim4 aut
700	1	a De Reijke, Theo M.4 aut
700	1	a De Santis, Maria4 aut
700	1	a Gillessen, Silke4 aut
700	1	a James, Nicholas4 aut
700	1	a Maclennan, Steven4 aut
700	1	a Palou, Juan4 aut
700	1	a Powles, Tom4 aut
700	1	a Ribal, Maria J.4 aut
700	1	a Shariat, Shahrokh F.4 aut
700	1	a Van Der Kwast, Theo4 aut
700	1	a Xylinas, Evanguelos4 aut
700	1	a Agarwal, Neeraj4 aut
700	1	a Arends, Tom4 aut
700	1	a Bamias, Aristotle4 aut
700	1	a Birtle, Alison4 aut
700	1	a Black, Peter C.4 aut
700	1	a Bochner, Bernard H.4 aut
700	1	a Bolla, Michel4 aut
700	1	a Boormans, Joost L.4 aut
700	1	a Bossi, Alberto4 aut
700	1	a Briganti, Alberto4 aut
700	1	a Brummelhuis, Iris4 aut
700	1	a Burger, Max4 aut
700	1	a Castellano, Daniel4 aut
700	1	a Cathomas, Richard4 aut
700	1	a Chiti, Arturo4 aut
700	1	a Choudhury, Ananya4 aut
700	1	a Compérat, Eva4 aut
700	1	a Crabb, Simon4 aut
700	1	a Culine, Stephane4 aut
700	1	a De Bari, Berardino4 aut
700	1	a De Blok, Willem4 aut
700	1	a De Visschere, Pieter J. L .4 aut
700	1	a Decaestecker, Karel4 aut
700	1	a Dimitropoulos, Konstantinos4 aut
700	1	a Dominguez-Escrig, Jose L4 aut
700	1	a Fanti, Stefano4 aut
700	1	a Fonteyne, Valerie4 aut
700	1	a Frydenberg, Mark4 aut
700	1	a Futterer, Jurgen J.4 aut
700	1	a Gakis, Georgios4 aut
700	1	a Geavlete, Bogdan4 aut
700	1	a Gontero, Paolo4 aut
700	1	a Grubmüller, Bernhard4 aut
700	1	a Hafeez, Shaista4 aut
700	1	a Hansel, Donna E.4 aut
700	1	a Hartmann, Arndt4 aut
700	1	a Hayne, Dickon4 aut
700	1	a Henry, Ann M.4 aut
700	1	a Hernandez, Virginia4 aut
700	1	a Herr, Harry4 aut
700	1	a Herrmann, Ken4 aut
700	1	a Hoskin, Peter4 aut
700	1	a Huguet, Jorge4 aut
700	1	a Jereczek-Fossa, Barbara A.4 aut
700	1	a Jones, Rob4 aut
700	1	a Kamat, Ashish M.4 aut
700	1	a Khoo, Vincent4 aut
700	1	a Kiltie, Anne E.4 aut
700	1	a Krege, Susanne4 aut
700	1	a Ladoire, Sylvain4 aut
700	1	a Lara, Pedro C.4 aut
700	1	a Leliveld, Annemarie4 aut
700	1	a Linares-Espinós, Estefania4 aut
700	1	a Løgager, Vibeke4 aut
700	1	a Lorch, Anja4 aut
700	1	a Loriot, Yohann4 aut
700	1	a Meijer, Richard4 aut
700	1	a Mir, M. Carmen4 aut
700	1	a Moschini, Marco4 aut
700	1	a Mostafid, Hugh4 aut
700	1	a Müller, Arndt-Christian4 aut
700	1	a Müller, Christoph R.4 aut
700	1	a N'Dow, James4 aut
700	1	a Necchi, Andrea4 aut
700	1	a Neuzillet, Yann4 aut
700	1	a Oddens, Jorg R.4 aut
700	1	a Oldenburg, Jan4 aut
700	1	a Osanto, Susanne4 aut
700	1	a Oyen, Wim J.G.4 aut
700	1	a Pacheco-Figueiredo, Luís4 aut
700	1	a Pappot, Helle4 aut
700	1	a Patel, Manish I.4 aut
700	1	a Pieters, Bradley R.4 aut
700	1	a Plass, Karin4 aut
700	1	a Remzi, Mesut4 aut
700	1	a Retz, Margitta4 aut
700	1	a Richenberg, Jonathan4 aut
700	1	a Rink, Michael4 aut
700	1	a Roghmann, Florian4 aut
700	1	a Rosenberg, Jonathan E.4 aut
700	1	a Rouprêt, Morgan4 aut
700	1	a Rouvière, Olivier4 aut
700	1	a Salembier, Carl4 aut
700	1	a Salminen, Antti4 aut
700	1	a Sargos, Paul4 aut
700	1	a Sengupta, Shomik4 aut
700	1	a Sherif, Amiru Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)amsh0008
700	1	a Smeenk, Robert J.4 aut
700	1	a Smits, Anita4 aut
700	1	a Stenzl, Arnulf4 aut
700	1	a Thalmann, George N.4 aut
700	1	a Tombal, Bertrand4 aut
700	1	a Turkbey, Baris4 aut
700	1	a Vahr Lauridsen, Susanne4 aut
700	1	a Valdagni, Riccardo4 aut
700	1	a Van Der Heijden, Antoine G.4 aut
700	1	a Van Poppel, Hein4 aut
700	1	a Vartolomei, Mihai D.4 aut
700	1	a Veskimäe, Erik4 aut
700	1	a Vilaseca, Antoni4 aut
700	1	a Vives Rivera, Franklin A.4 aut
700	1	a Wiegel, Thomas4 aut
700	1	a Wiklund, Peteru Karolinska Institutet4 aut
700	1	a Williams, Andrew4 aut
700	1	a Zigeuner, Richard4 aut
700	1	a Horwich, Alan4 aut
710	2	a Umeå universitetb Urologi och andrologi4 org
773	0	t European Urologyd : Elsevierg 77:2, s. 223-250q 77:2<223-250x 0302-2838x 1873-7560
856	4	u https://pure.rug.nl/ws/files/132599496/1_s2.0_S0302283819307638_main.pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166179
856	4 8	u https://doi.org/10.1016/j.eururo.2019.09.035
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:142749555

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Av författaren/redakt...: Witjes, J. Alfre ...; Babjuk, Marek; Bellmunt, Joaqui ...; Bruins, H. Maxim; De Reijke, Theo ...; De Santis, Maria; visa fler...; Gillessen, Silke; James, Nicholas; Maclennan, Steve ...; Palou, Juan; Powles, Tom; Ribal, Maria J.; Shariat, Shahrok ...; Van Der Kwast, T ...; Xylinas, Evangue ...; Agarwal, Neeraj; Arends, Tom; Bamias, Aristotl ...; Birtle, Alison; Black, Peter C.; Bochner, Bernard ...; Bolla, Michel; Boormans, Joost ...; Bossi, Alberto; Briganti, Albert ...; Brummelhuis, Iri ...; Burger, Max; Castellano, Dani ...; Cathomas, Richar ...; Chiti, Arturo; Choudhury, Anany ...; Compérat, Eva; Crabb, Simon; Culine, Stephane; De Bari, Berardi ...; De Blok, Willem; De Visschere, Pi ...; Decaestecker, Ka ...; Dimitropoulos, K ...; Dominguez-Escrig ...; Fanti, Stefano; Fonteyne, Valeri ...; Frydenberg, Mark; Futterer, Jurgen ...; Gakis, Georgios; Geavlete, Bogdan; Gontero, Paolo; Grubmüller, Bern ...; Hafeez, Shaista; Hansel, Donna E.; Hartmann, Arndt; Hayne, Dickon; Henry, Ann M.; Hernandez, Virgi ...; Herr, Harry; Herrmann, Ken; Hoskin, Peter; Huguet, Jorge; Jereczek-Fossa, ...; Jones, Rob; Kamat, Ashish M.; Khoo, Vincent; Kiltie, Anne E.; Krege, Susanne; Ladoire, Sylvain; Lara, Pedro C.; Leliveld, Annema ...; Linares-Espinós, ...; Løgager, Vibeke; Lorch, Anja; Loriot, Yohann; Meijer, Richard; Mir, M. Carmen; Moschini, Marco; Mostafid, Hugh; Müller, Arndt-Ch ...; Müller, Christop ...; N'Dow, James; Necchi, Andrea; Neuzillet, Yann; Oddens, Jorg R.; Oldenburg, Jan; Osanto, Susanne; Oyen, Wim J.G.; Pacheco-Figueire ...; Pappot, Helle; Patel, Manish I.; Pieters, Bradley ...; Plass, Karin; Remzi, Mesut; Retz, Margitta; Richenberg, Jona ...; Rink, Michael; Roghmann, Floria ...; Rosenberg, Jonat ...; Rouprêt, Morgan; Rouvière, Olivie ...; Salembier, Carl; Salminen, Antti; Sargos, Paul; Sengupta, Shomik; Sherif, Amir; Smeenk, Robert J ...; Smits, Anita; Stenzl, Arnulf; Thalmann, George ...; Tombal, Bertrand; Turkbey, Baris; Vahr Lauridsen, ...; Valdagni, Riccar ...; Van Der Heijden, ...; Van Poppel, Hein; Vartolomei, Miha ...; Veskimäe, Erik; Vilaseca, Antoni; Vives Rivera, Fr ...; Wiegel, Thomas; Wiklund, Peter; Williams, Andrew; Zigeuner, Richar ...; Horwich, Alan; visa färre...

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