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Atrial fibrillation history impact on catheter ablation outcome : Findings from the ESC-EHRA atrial fibrillation ablation long-term registry
- Stabile, Giuseppe (author)
- Trines, Serge A (author)
- Arbelo, Elena (author)
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- Dagres, Nikolaos (author)
- Brugada, Josep (author)
- Kautzner, Josef (author)
- Pokushalov, Evgeny (author)
- Maggioni, Aldo P (author)
- Laroche, Cecile (author)
- Anselmino, Matteo (author)
- Beinart, Roy (author)
- Traykov, Vassil (author)
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- (creator_code:org_t)
- 2019-01-22
- 2019
- English.
- In: Pacing and Clinical Electrophysiology. - : Wiley. - 0147-8389 .- 1540-8159. ; 42:3, s. 313-320
- Journal article (peer-reviewed)
Abstract
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- BACKGROUND: Atrial fibrillation (AF) promotes atrial remodeling that in turn promote AF perpetuation. The aim of our study was to investigate the impact of AF history length on one-year outcome of AF catheter ablation in a cohort of patients enrolled in the Atrial Fibrillation Ablation Registry.METHODS: We described the real-life clinical epidemiology, therapeutic strategies and the short- and mid-term outcomes of 1948 patients (71.9% with paroxysmal AF) undergoing AF ablation procedures, stratified according to AF history duration (< 2 years or ≥ 2 years).RESULTS: The mean AF history duration was 46,2±57,4 months, 592 patients had an AF history duration < 2 years (mean 10,2±5,9 months), and 1356 patients ≥ 2 years (mean 75,5±63,5 months) (P < 0.001). Patients with AF history duration < 2 years were younger, had a lower incidence of hypertension, coronary artery disease, hypertrophic cardiomyopathy and had a lower CHA2 DS2 -VaSc Score. At one year, the logrank test showed a lower incidence of AF recurrence in patients with AF history duration < 2 years (28.9%) than in patients with AF history duration ≥ 2 years (34.0%) (P = 0.037). AF history duration ≥ 2 years, overall ablation procedure duration, hypertension and chronic kidney disease were all predictors of recurrences after the blanking period.CONCLUSIONS: In this multicenter registry, performing catheter ablation in patients with an AF history ≥ 2 years was associated with higher rates of AF recurrences at one year. Since cumulative time in AF in not necessarily equivalent to AF history, its role remains to be clarified.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Atrial fibrillation
- Atrial fibrillation duration
- Catheter ablation
- Mid-term outcome
- recurrence predictors
- Cardiology
- Kardiologi
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Trines, Serge A
- Arbelo, Elena
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- Pokushalov, Evge ...
- Maggioni, Aldo P
- Laroche, Cecile
- Anselmino, Matte ...
- Beinart, Roy
- Traykov, Vassil
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