Sökning: WFRF:(Moons Karel G M) > Comparison of progn...
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000 | 07499naa a2200949 4500 | |
001 | oai:DiVA.org:umu-146375 | |
003 | SwePub | |
008 | 180406s2019 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:9b52bdcc-ae92-4363-abeb-5fbfa89f8fc6 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1463752 URI |
024 | 7 | a https://doi.org/10.1136/gutjnl-2017-3157302 DOI |
024 | 7 | a https://lup.lub.lu.se/record/9b52bdcc-ae92-4363-abeb-5fbfa89f8fc62 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Smith, Toddu Imperial College London4 aut |
245 | 1 0 | a Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals :b a systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies |
264 | c 2018-04-03 | |
264 | 1 | b BMJ Publishing Group Ltd,c 2019 |
338 | a electronic2 rdacarrier | |
520 | a OBJECTIVE: To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts.DESIGN: Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK Biobank. The performance of the models to predict the occurrence of colorectal cancer within 5 or 10 years after study enrolment was assessed by discrimination (C-statistic) and calibration (plots of observed vs predicted probability).RESULTS: The systematic review and its update identified 16 models from 8 publications (8 colorectal, 5 colon and 3 rectal). The number of participants included in each model validation ranged from 41 587 to 396 515, and the number of cases ranged from 115 to 1781. Eligible and ineligible participants across the models were largely comparable. Calibration of the models, where assessable, was very good and further improved by recalibration. The C-statistics of the models were largely similar between validation cohorts with the highest values achieved being 0.70 (95% CI 0.68 to 0.72) in the UK Biobank and 0.71 (95% CI 0.67 to 0.74) in EPIC.CONCLUSION: Several of these non-invasive models exhibited good calibration and discrimination within both external validation populations and are therefore potentially suitable candidates for the facilitation of risk stratification in population-based colorectal screening programmes. Future work should both evaluate this potential, through modelling and impact studies, and ascertain if further enhancement in their performance can be obtained. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a cancer prevention | |
653 | a colorectal cancer | |
653 | a colorectal cancer screening | |
653 | a epidemiology | |
653 | a medical statistics | |
653 | a cancer prevention | |
653 | a colorectal cancer | |
653 | a colorectal cancer screening | |
653 | a epidemiology | |
653 | a medical statistics | |
700 | 1 | a Muller, David C.u Imperial College London4 aut |
700 | 1 | a Moons, Karel G. M.u University Medical Center Utrecht4 aut |
700 | 1 | a Cross, Amanda J.u Imperial College London,International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Johansson, Mattiasu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Fagherazzi, Guyu Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Peeters, Petra H. M.u University Medical Center Utrecht4 aut |
700 | 1 | a Severi, Gianlucau Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Hüsing, Anikau German Cancer Research Centre4 aut |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Tjonneland, Anneu Danish Cancer Society4 aut |
700 | 1 | a Olsen, Anjau Danish Cancer Society4 aut |
700 | 1 | a Overvad, Kimu Aarhus University4 aut |
700 | 1 | a Bonet, Catalinau Bellvitge University Hospital-IDIBELL4 aut |
700 | 1 | a Rodriguez-Barranco, Miguelu Andalusian School Of Public Health (EASP)4 aut |
700 | 1 | a Huerta, Jose Mariau CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Barricarte Gurrea, Aureliou CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Bradbury, Kathryn E.u University of Oxford4 aut |
700 | 1 | a Trichopoulou, Antoniau Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Bamia, Christinau Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Orfanos, Philipposu National and Kapodistrian University of Athens4 aut |
700 | 1 | a Palli, Domenicou Cancer Research and Prevention Institute (ISPO)4 aut |
700 | 1 | a Pala, Valeriau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Vineis, Paolou Italian Institute for Genomic Medicine (IIGM)4 aut |
700 | 1 | a Bueno-de-Mesquita, Basu National Institute for Public Health and the Environment (RIVM)4 aut |
700 | 1 | a Ohlsson, Bodilu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)kir-boh |
700 | 1 | a Harlid, Sophiau Umeå University,Umeå universitet,Onkologi4 aut0 (Swepub:lu)mikr-sha |
700 | 1 | a van Guelpen, Bethanyu Umeå University,Umeå universitet,Onkologi4 aut0 (Swepub:umu)beyvan99 |
700 | 1 | a Skeie, Guriu UiT The Arctic University of Norway, Tromsø4 aut |
700 | 1 | a Weiderpass, Elisabeteu Cancer Registry of Norway, Institute of Population-Based Cancer Research4 aut |
700 | 1 | a Jenab, Mazda4 aut |
700 | 1 | a Murphy, Neilu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
700 | 1 | a Gunter, Marc J.u International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Aleksandrova, Krasimira Jekovau German Institute of Human Nutrition4 aut |
700 | 1 | a Tzoulaki, Ioannau Imperial College London4 aut |
710 | 2 | a Imperial College Londonb University Medical Center Utrecht4 org |
773 | 0 | t Gutd : BMJ Publishing Group Ltdg 68, s. 672-683q 68<672-683x 0017-5749x 1468-3288 |
856 | 4 | u https://doi.org/10.1136/gutjnl-2017-315730y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1195770/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://gut.bmj.com/content/gutjnl/68/4/672.full.pdf |
856 | 4 | u http://dx.doi.org/10.1136/gutjnl-2017-315730x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-146375 |
856 | 4 8 | u https://doi.org/10.1136/gutjnl-2017-315730 |
856 | 4 8 | u https://lup.lub.lu.se/record/9b52bdcc-ae92-4363-abeb-5fbfa89f8fc6 |
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