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Association of seru...
Association of serum 25-hydroxyvitamin D (25-OHD) concentrations with maternal sex steroids and IGF-1 hormones during pregnancy
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Toriola, Adetunji T (författare)
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Surcel, Helja-Marja (författare)
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Husing, Anika (författare)
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- Grankvist, Kjell (författare)
- Umeå universitet,Klinisk kemi
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- Lakso, Hans-Åke (författare)
- Umeå universitet,Institutionen för medicinsk biovetenskap
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Schock, Helena (författare)
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- Lundin, Eva (författare)
- Umeå universitet,Patologi
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Lehtinen, Matti (författare)
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Lukanova, Annekatrin (författare)
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(creator_code:org_t)
- 2011-03-09
- 2011
- Engelska.
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Ingår i: Cancer Causes and Control. - : Springer Netherlands. - 0957-5243 .- 1573-7225. ; 22:6, s. 925-928
- Relaterad länk:
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Vitamin D may influence circulating levels of sex steroid hormones in women during reproductive life, but associations in pregnant women have not been explored.METHODS: Correlation and linear regression models were used to assess the association between sex steroids, (estradiol, progesterone, 17-hydroxyprogesterone, testosterone, and androstenedione), IGF-1, and serum 25-hydroxyvitamin D (25-OHD) concentrations during the first trimester of pregnancy in 106 cancer-free women from the Finnish Maternity Cohort.RESULTS: There was no significant association of serum 25-OHD with any of the hormones measured. One-unit increase in serum 25-OHD concentration was associated with a non-significant 6% increase in estradiol concentrations. Multiparous women had higher levels of vitamin D (40.4 vs. 32.9 nmol/L, p-value = 0.01) than primiparous women.CONCLUSION: Our study does not support an association between maternal serum 25-OHD levels and sex steroids or IGF-I concentrations during the first trimester of pregnancy.
Nyckelord
- Acupuncture
- exercise
- hemostatic factor
- insulin resistance
- adipocyte size
- plasminogen activator inhibitor 1
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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