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Effect of prenatal and postnatal exposure to home renovation on the risk of common cold in preschool children

Fu, Xiaoli (författare)
Zhengzhou Univ, Sch Publ Hlth, Zhengzhou, Peoples R China.
Lu, Chan (författare)
Cent South Univ, XiangYa Sch Publ Hlth, Changsha, Peoples R China.
Zhang, Yinping (författare)
Tsinghua Univ, Sch Architecture, Beijing, Peoples R China.
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Li, Baizhan (författare)
Chongqing Univ, Key Lab Three Gorges Reservoir Reg Ecoenvironm, Chongqing, Peoples R China.
Zhao, Zhuohui (författare)
Fudan Univ, Dept Environm Hlth, Shanghai, Peoples R China.
Huang, Chen (författare)
Univ Shanghai Sci & Technol, Sch Environm & Architecture, Dept Bldg Environm & Energy Engn, Shanghai, Peoples R China.
Zhang, Xin (författare)
Shanxi Univ, Inst Environm Sci, Taiyuan, Peoples R China.
Qian, Hua (författare)
Southeast Univ, Sch Energy & Environm, Nanjing, Peoples R China.
Wang, Juan (författare)
Uppsala universitet,Arbets- och miljömedicin
Liu, Wei (författare)
Tsinghua Univ, Sch Architecture, Beijing, Peoples R China.;Chongqing Univ Sci & Technol, Inst Hlth & Environm, Chongqing, Peoples R China.
Sun, Yuexia (författare)
Tianjin Univ, Sch Environm Sci & Engn, Tianjin, Peoples R China.
Norbäck, Dan (författare)
Uppsala universitet,Arbets- och miljömedicin
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Zhengzhou Univ, Sch Publ Hlth, Zhengzhou, Peoples R China Cent South Univ, XiangYa Sch Publ Hlth, Changsha, Peoples R China. (creator_code:org_t)
2022-06-13
2022
Engelska.
Ingår i: Indoor Air. - : John Wiley & Sons. - 0905-6947 .- 1600-0668. ; 32:6
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Common cold is usually considered to be associated with outdoor climate, but the evidence linking with indoor environmental factors is lacking. The role of indoor renovations during which critical timing window on childhood common cold remains unclear. Therefore, we investigated the effect of exposure to new furniture and/or redecoration during prenatal and postnatal periods on the occurrence and duration of common cold in preschool children. We conducted a retrospective cohort study of 39 782 children aged 3-6 years in seven cities of China. The occurrence and duration of common cold in children, and their lifetime exposures to indoor new furniture and redecoration (including pregnancy, the first year of life, and after one year old) were assessed using a questionnaire administered by the parents. Associations between high frequency (>5 colds) and long duration (>= 2 weeks per cold) of common cold during past 12 months and exposure to indoor new furniture/redecoration were examined by logistic regression models in terms of odds ratio (OR) and 95% confidence interval (CI). We found that the prevalence of high frequency and long duration of common cold in preschool children in China were, respectively, 9.2% and 11.9%. Frequent common cold was significantly associated with exposure to indoor new furniture/redecoration during pregnancy, first year, and after 1 year old, respectively, with the ORs (95% CI) = 1.25 (1.12-1.39), 1.11 (1.00-1.25), and 1.09 (1.01-1.18). Furthermore, childhood long duration per cold was associated with exposure to indoor new furniture/redecoration during pregnancy with OR (95% CI) of 1.14 (1.03-1.25) but not with postnatal exposure. We identified that prenatal exposure to home renovation was more critical than postnatal exposure for an increased risk of high frequency and long duration of common cold. Sensitivity analysis showed that the association between prenatal exposure to indoor renovations and the risk of childhood common cold was consistent and robust, and the associations were modified by some personal and indoor environmental factors. Our findings indicated that prenatal and postnatal exposure to home renovation played an important role in the risk of childhood common cold, supporting the hypothesis of "fetal origin of childhood infection."

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

childhood
common cold
early-life exposure
house redecoration
indoor new furniture

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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