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Genome-wide associa...
Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study
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- Cai, Lina (author)
- University of Cambridge
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- Wheeler, Eleanor (author)
- University of Cambridge
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- Kerrison, Nicola D. (author)
- University of Cambridge
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- Luan, Jian'an (author)
- University of Cambridge
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- Deloukas, Panos (author)
- Queen Mary University
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- Franks, Paul W. (author)
- Umeå University,Lund University,Lunds universitet,Umeå universitet,Näringsforskning,Department of Clinical Sciences, Clinical Research Center, Skåne University Hospital, Lund University, 20502, Malmö, Sweden,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups
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- Amiano, Pilar (author)
- Biodonostia Health Research Institute
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- Ardanaz, Eva (author)
- Health Research Institute of Navarra (IDISNA)
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- Bonet, Catalina (author)
- Bellvitge Biomedical Research Institute
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- Fagherazzi, Guy (author)
- Luxembourg Institute of Health,Institut Gustave Roussy
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- Groop, Leif C. (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Skåne University Hospital
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- Kaaks, Rudolf (author)
- German Cancer Research Centre
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- Huerta, Jose Maria (author)
- Murcia Regional Health Council,CIBER Epidemiology and Public Health (CIBERESP)
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- Masala, Giovanna (author)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
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- Nilsson, Peter M. (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital
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- Overvad, Kim (author)
- Aarhus University,Aalborg University Hospital
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- Pala, Valeria (author)
- Istituto Nazionale dei Tumori
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- Panico, Salvatore (author)
- University of Naples Federico II
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- Rodriguez-Barranco, Miguel (author)
- Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP)
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- Rolandsson, Olov (author)
- Umeå University,Umeå universitet,Allmänmedicin
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- Sacerdote, Carlotta (author)
- Citta' della Salute e della Scienza Hospital-University of Turin
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- Schulze, Matthias B. (author)
- University of Potsdam,German Center for Diabetes Research
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- Spijkerman, Annemieke M. W. (author)
- National Institute for Public Health and the Environment (RIVM)
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- Tjonneland, Anne (author)
- Danish Cancer Society
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Tumino, Rosario (author)
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- van der Schouw, Yvonne T. (author)
- University Medical Center Utrecht
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- Sharp, Stephen J. (author)
- University of Cambridge
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- Forouhi, Nita G. (author)
- University of Cambridge
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- Riboli, Elio (author)
- Imperial College London
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- McCarthy, Mark I. (author)
- University of Oxford,Wellcome Trust Centre for Human Genetics,Oxford University Hospital
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- Barroso, Ines (author)
- University of Exeter
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- Langenberg, Claudia (author)
- University of Cambridge
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- Wareham, Nicholas J. (author)
- University of Cambridge
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(creator_code:org_t)
- 2020-11-13
- 2020
- English.
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In: Scientific Data. - : Nature Publishing Group. - 2052-4463. ; 7:1
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of the largest prospective studies of T2D. Established as a nested case-cohort study to investigate the interplay between genetic and lifestyle behavioural factors on the risk of T2D, a total of 12,403 individuals were identified as incident T2D cases, and a representative sub-cohort of 16,154 individuals was selected from a larger cohort of 340,234 participants with a follow-up time of 3.99 million person-years. We describe the results from a genome-wide association analysis between more than 8.9 million SNPs and T2D risk among 22,326 individuals (9,978 cases and 12,348 non-cases) from the EPIC-InterAct study. The summary statistics to be shared provide a valuable resource to facilitate further investigations into the genetics of T2D.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Cai, Lina
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Wheeler, Eleanor
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Kerrison, Nicola ...
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Luan, Jian'an
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Deloukas, Panos
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Franks, Paul W.
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show more...
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Amiano, Pilar
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Ardanaz, Eva
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Bonet, Catalina
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Fagherazzi, Guy
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Groop, Leif C.
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Kaaks, Rudolf
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Huerta, Jose Mar ...
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Masala, Giovanna
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Nilsson, Peter M ...
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Overvad, Kim
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Pala, Valeria
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Panico, Salvator ...
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Rodriguez-Barran ...
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Rolandsson, Olov
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Sacerdote, Carlo ...
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Schulze, Matthia ...
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Spijkerman, Anne ...
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Tjonneland, Anne
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Tumino, Rosario
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van der Schouw, ...
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Sharp, Stephen J ...
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Forouhi, Nita G.
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Riboli, Elio
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McCarthy, Mark I ...
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Barroso, Ines
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Langenberg, Clau ...
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Wareham, Nichola ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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Scientific Data
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Umeå University
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Lund University