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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07022naa a2201345 4500 | |
| 001 | oai:gup.ub.gu.se/66317 | |
| 003 | SwePub | |
| 008 | 240528s2007 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:umu-8961 | |
| 009 | oai:DiVA.org:uu-14458 | |
| 009 | oai:lup.lub.lu.se:edc9938a-8598-40f9-b7ca-1aad6b787cf7 | |
| 009 | oai:DiVA.org:liu-108701 | |
| 009 | oai:prod.swepub.kib.ki.se:115877412 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/663172 URI |
| 024 | 7 | a https://doi.org/10.1038/sj.gene.63644062 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-89612 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-144582 URI |
| 024 | 7 | a https://lup.lub.lu.se/record/11405072 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1087012 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1158774122 URI |
| 040 | a (SwePub)gud (SwePub)umud (SwePub)uud (SwePub)lud (SwePub)liud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sedimbi, S. K.u Karolinska Institutet4 aut |
| 245 | 1 0 | a SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients |
| 264 | c 2007-06-07 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2007 |
| 500 | a Group Author(s): Swedish Childhood Diabetes | |
| 520 | a SUMO4 M55V, located in IDDM5, has been a focus for debate because of its association to type I diabetes (TIDM) in Asians but not in Caucasians. The current study aims to test the significance of M55V association to TIDM in a large cohort of Swedish Caucasians, and to test whether M55V is associated in those carrying human leukocyte antigen (HLA) class II molecules. A total of 673 TIDM patients and 535 age- and sex-matched healthy controls were included in the study. PCR-RFLP was performed to identify the genotype and allele variations. Our data suggest that SUMO4 M55V is not associated with susceptibility to TIDM by itself. When we stratified our patients and controls based on heterozygosity for HLA-DR3/DR4 and SUMO4 genotypes, we found that presence of SUMO4 GG increased further the relative risk conferred by HLA-DR3/DR4 to TIDM, whereas SUMO4 AA decreased the risk. From the current study, we conclude that SUMO4 M55V is associated with TIDM in association with high-risk HLA-DR3 and DR4, but not by itself. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 653 | a Adolescent | |
| 653 | a Adult | |
| 653 | a Alleles | |
| 653 | a Case-Control Studies | |
| 653 | a Child | |
| 653 | a Child | |
| 653 | a Preschool | |
| 653 | a Cohort Studies | |
| 653 | a Diabetes Mellitus | |
| 653 | a Type 1/*genetics/immunology | |
| 653 | a Female | |
| 653 | a Genetic Predisposition to Disease | |
| 653 | a Genotype | |
| 653 | a HLA-DR3 Antigen/*genetics/immunology | |
| 653 | a HLA-DR4 Antigen/*genetics/immunology | |
| 653 | a Haplotypes | |
| 653 | a Humans | |
| 653 | a Infant | |
| 653 | a Infant | |
| 653 | a Newborn | |
| 653 | a Male | |
| 653 | a Polymorphism | |
| 653 | a Single Nucleotide | |
| 653 | a Small Ubiquitin-Related Modifier Proteins/*genetics/immunology | |
| 653 | a Sweden | |
| 653 | a Adolescent | |
| 653 | a MEDICINE | |
| 700 | 1 | a Luo, X. R.u Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden4 aut |
| 700 | 1 | a Sanjeevi, C. B.u Karolinska Institutet4 aut |
| 700 | 1 | a Lernmark, Ake4 aut |
| 700 | 1 | a Landin-Olsson, Monau Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-mla |
| 700 | 1 | a Arnqvist, H.u Linköpings universitet,Cellbiologi,Hälsouniversitetet4 aut |
| 700 | 1 | a Björck, E.4 aut |
| 700 | 1 | a Nyström, L.4 aut |
| 700 | 1 | a Ohlson, L. O.4 aut |
| 700 | 1 | a Schersten, B.4 aut |
| 700 | 1 | a Östman, J.4 aut |
| 700 | 1 | a Aili, M.4 aut |
| 700 | 1 | a Baath, L. E.4 aut |
| 700 | 1 | a Carlsson, E.4 aut |
| 700 | 1 | a Edenwall, H.4 aut |
| 700 | 1 | a Forsander, Gun,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xfgunj |
| 700 | 1 | a Granström, B. W.4 aut |
| 700 | 1 | a Gustavsson, I.4 aut |
| 700 | 1 | a Hanas, R.4 aut |
| 700 | 1 | a Hellenberg, L.4 aut |
| 700 | 1 | a Hellgren, H.4 aut |
| 700 | 1 | a Holmberg, E.4 aut |
| 700 | 1 | a Hornell, H.4 aut |
| 700 | 1 | a Ivarsson, S. A.4 aut |
| 700 | 1 | a Johansson, C.4 aut |
| 700 | 1 | a Jonsell, G.4 aut |
| 700 | 1 | a Kockum, K.4 aut |
| 700 | 1 | a Lindblad, B.4 aut |
| 700 | 1 | a Lindh, A.4 aut |
| 700 | 1 | a Ludvigsson, Johnnyu Östergötlands Läns Landsting,Linköpings universitet,Pediatrik,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping4 aut0 (Swepub:liu)johlu29 |
| 700 | 1 | a Myrdal, U.4 aut |
| 700 | 1 | a Neiderud, J.4 aut |
| 700 | 1 | a Segnestam, K.4 aut |
| 700 | 1 | a Sjöblad, S.4 aut |
| 700 | 1 | a Skogsberg, L.4 aut |
| 700 | 1 | a Strömberg, L.4 aut |
| 700 | 1 | a Stahle, U.4 aut |
| 700 | 1 | a Thalme, B.4 aut |
| 700 | 1 | a Tullus, K.4 aut |
| 700 | 1 | a Tuvemo, Torstenu Uppsala universitet,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forskning/Gustafsson4 aut0 (Swepub:uu)torstuve |
| 700 | 1 | a Wallensteen, M.4 aut |
| 700 | 1 | a Westphal, Otto,d 1935u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xwesot |
| 700 | 1 | a Dahlquist, Giselau Umeå universitet,Pediatrik4 aut0 (Swepub:umu)gida0001 |
| 700 | 1 | a Aman, J.u Uppsala universitet,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forksning/Gustafsson4 aut |
| 710 | 2 | a Karolinska Institutetb Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden4 org |
| 773 | 0 | t Genes Immund : Springer Science and Business Media LLCg 8:6, s. 518-21q 8:6<518-21x 1466-4879x 1476-5470 |
| 856 | 4 | u https://www.nature.com/articles/6364406.pdf |
| 856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17554341&dopt=Citation |
| 856 | 4 | u http://dx.doi.org/10.1038/sj.gene.6364406y FULLTEXT |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/66317 |
| 856 | 4 8 | u https://doi.org/10.1038/sj.gene.6364406 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-8961 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-14458 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1140507 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-108701 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:115877412 |
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- Sedimbi, S. K.
- Luo, X. R.
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- Lernmark, Ake
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- Björck, E.
- Nyström, L.
- Ohlson, L. O.
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- Aili, M.
- Baath, L. E.
- Carlsson, E.
- Edenwall, H.
- Forsander, Gun, ...
- Granström, B. W.
- Gustavsson, I.
- Hanas, R.
- Hellenberg, L.
- Hellgren, H.
- Holmberg, E.
- Hornell, H.
- Ivarsson, S. A.
- Johansson, C.
- Jonsell, G.
- Kockum, K.
- Lindblad, B.
- Lindh, A.
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- Myrdal, U.
- Neiderud, J.
- Segnestam, K.
- Sjöblad, S.
- Skogsberg, L.
- Strömberg, L.
- Stahle, U.
- Thalme, B.
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