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Pharmacokinetics of doxorubicin in children with acute lymphoblastic leukemia: multi-institutional collaborative study.

Frost, Britt-Marie (author)
Uppsala universitet,Institutionen för kvinnors och barns hälsa,University Children's Hospital, Uppsala, Sweden,Barnonkologisk forskning/Lönnerholm
Eksborg, S (author)
Karolinska Institutet,Karolinska Pharmacy, Karolinska Hospital, Stockholm, Sweden
Björk, O (author)
Björk, O., Department of Pediatric Oncology, Karolinska Hospital, Stockholm, Sweden
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Abrahamsson, Jonas, 1954 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics,Department of Pediatrics, Queen Silvias Child and Adolescent Hospital, Göteborg, Sweden
Behrendtz, M (author)
Östergötlands Läns Landsting,Barn- och ungdomsmedicinska kliniken US
Castor, Anders (author)
Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Pediatrics, University Hospital, Lund, Sweden
Forestier, E (author)
Karolinska Pharmacy, Karolinska Hospital, Stockholm, Sweden
Lönnerholm, Gudmar (author)
Uppsala universitet,Institutionen för kvinnors och barns hälsa,Lönnerholm, G., University Children's Hospital, Uppsala, Sweden, Department of Pediatrics, Umeå University Hospital, Umeå, Sweden,Barnonkologisk forskning/Lönnerholm
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 (creator_code:org_t)
2002-04-22
2002
English.
In: Medical and pediatric oncology. - : Wiley. - 0098-1532 .- 1096-911X. ; 38, s. 329-
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • In adults, it has been shown that the pharmacokinetics of doxorubicin are highly variable, despite standardization of the dose based on body surface area (BSA). The purpose of this study was to determine the plasma concentrations of doxorubicin and its active metabolite doxorubicinol in children treated for acute lymphoblastic leukemia (ALL).

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Keyword

Adolescent
Age Factors
Antineoplastic Agents
administration & dosage
pharmacokinetics
Child
Child
Preschool
Doxorubicin
administration & dosage
pharmacokinetics
Female
Humans
Infant
Infusions
Intravenous
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
drug therapy
childhood cancer
doxorubicin
anthracycline
acute
lymphoblastic leukemia
Acute lymphoblastic leukemia
NATURAL SCIENCES

Publication and Content Type

ref (subject category)
art (subject category)

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