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Sökning: WFRF:(Dahm Christina C.) > (2010-2014) > Reproductive Factor...

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FältnamnIndikatorerMetadata
00005337naa a2200829 4500
001oai:lup.lub.lu.se:874d932e-f7c9-4608-9f80-4e3e1411d4d2
003SwePub
008160401s2010 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-38267
0247 a https://lup.lub.lu.se/record/17280462 URI
0247 a https://doi.org/10.1158/1055-9965.EPI-10-04472 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-382672 URI
040 a (SwePub)lud (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Michaud, Dominique S.4 aut
2451 0a Reproductive Factors and Exogenous Hormone Use in Relation to Risk of Glioma and Meningioma in a Large European Cohort Study
264 1c 2010
520 a Background: The etiologies of glioma and meningioma tumors are largely unknown. Although reproductive hormones are thought to influence the risk of these tumors, epidemiologic data are not supportive of this hypothesis; however, few cohort studies have published on this topic. We examined the relation between reproductive factors and the risk of glioma and meningioma among women in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: After a mean of 8.4 years of follow-up, 193 glioma and 194 meningioma cases were identified among 276,212 women. Information on reproductive factors and hormone use was collected at baseline. Cox proportional hazard regression was used to determine hazard ratios (HR) and 95% confidence intervals (95% CI). Results: No associations were observed between glioma or meningioma risk and reproductive factors, including age at menarche, parity, age at first birth, menopausal status, and age at menopause. A higher risk of meningioma was observed among postmenopausal women who were current users of hormone replacement therapy (HR, 1.79; 95% CI, 1.18-2.71) compared with never users. Similarly, current users of oral contraceptives were at higher risk of meningioma than never users (HR, 3.61; 95% CI, 1.75-7.46). Conclusion: Our results do not support a role for estrogens and glioma risk. Use of exogenous hormones, especially current use, seems to increase meningioma risk. However, these findings could be due to diagnostic bias and require confirmation. Impact: Elucidating the role of hormones in brain tumor development has important implications and needs to be further examined using biological measurements. Cancer Epidemiol Biomarkers Prev; 19(10); 2562-9. (C) 2010 AACR.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
7001 a Gallo, Valentina4 aut
7001 a Schlehofer, Brigitte4 aut
7001 a Tjonneland, Anne4 aut
7001 a Olsen, Anja4 aut
7001 a Overvad, Kim4 aut
7001 a Dahm, Christina C.4 aut
7001 a Kaaks, Rudolf4 aut
7001 a Lukanova, Annekatrin4 aut
7001 a Boeing, Heiner4 aut
7001 a Schuetze, Madlen4 aut
7001 a Trichopoulou, Antonia4 aut
7001 a Bamia, Christina4 aut
7001 a Kyrozis, Andreas4 aut
7001 a Sacerdote, Carlotta4 aut
7001 a Agnoli, Claudia4 aut
7001 a Palli, Domenico4 aut
7001 a Tumino, Rosario4 aut
7001 a Mattiello, Amalia4 aut
7001 a Bueno-de-Mesquita, H. Bas4 aut
7001 a Ros, Martine M.4 aut
7001 a Peeters, Petra H. M.4 aut
7001 a van Gils, Carla H.4 aut
7001 a Lund, Eiliv4 aut
7001 a Bakken, Kjersti4 aut
7001 a Gram, Inger T.4 aut
7001 a Barricarte, Aurelio4 aut
7001 a Navarro, Carmen4 aut
7001 a Dorronsoro, Miren4 aut
7001 a Jose Sanchez, Maria4 aut
7001 a Rodriguez, Laudina4 aut
7001 a Duell, Eric J.4 aut
7001 a Hallmans, Göran,d 1947-u Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001
7001 a Melin, Beatriceu Umeå universitet,Onkologi4 aut0 (Swepub:umu)bema0010
7001 a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma
7001 a Borgquist, Signeu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ront-sbo
7001 a Khaw, Kay-Tee4 aut
7001 a Wareham, Nick4 aut
7001 a Allen, Naomi E.4 aut
7001 a Tsilidis, Konstantinos K.4 aut
7001 a Romieu, Isabelle4 aut
7001 a Rinaldi, Sabina4 aut
7001 a Vineis, Paolo4 aut
7001 a Riboli, Elio4 aut
7102 a Umeå universitetb Näringsforskning4 org
7730 t Cancer Epidemiology Biomarkers & Preventiong 19:10, s. 2562-2569q 19:10<2562-2569x 1538-7755x 1055-9965
8564 u http://dx.doi.org/10.1158/1055-9965.EPI-10-0447y FULLTEXT
8564 8u https://lup.lub.lu.se/record/1728046
8564 8u https://doi.org/10.1158/1055-9965.EPI-10-0447
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-38267

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