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Duration of Venoart...
Duration of Venoarterial Extracorporeal Membrane Oxygenation and Mortality in Postcardiotomy Cardiogenic Shock
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- Mariscalco, Giovanni (författare)
- Glenfield Hospital
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- El-Dean, Zein (författare)
- Glenfield Hospital
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- Yusuff, Hakeem (författare)
- Glenfield Hospital
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- Fux, Thomas (författare)
- Karolinska Institutet
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- Dell'Aquila, Angelo M. (författare)
- University Hospital Münster
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- Jónsson, Kristján (författare)
- Sahlgrenska University Hospital
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- Ragnarsson, Sigurdur (författare)
- Lund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Fiore, Antonio (författare)
- Henri Mondor Hospital
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- Dalén, Magnus (författare)
- Karolinska Institutet
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- di Perna, Dario (författare)
- Robert Debré University Hospital
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- Gatti, Giuseppe (författare)
- University Hospital Of Trieste
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- Juvonen, Tatu (författare)
- University of Oulu,Helsinki University Central Hospital
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- Zipfel, Svante (författare)
- University Medical Center Hamburg-Eppendorf
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- Perrotti, Andrea (författare)
- University Hospital Jean Minjoz
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- Bounader, Karl (författare)
- Pontchaillou University Hospital
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- Alkhamees, Khalid (författare)
- Prince Sultan Cardiac Center
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- Loforte, Antonio (författare)
- University of Bologna
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- Lechiancole, Andrea (författare)
- University Hospital of Udine
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- Pol, Marek (författare)
- Institute for Clinical and Experimental Medicine (IKEM)
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- Spadaccio, Cristiano (författare)
- Golden Jubilee National Hospital
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- Pettinari, Matteo (författare)
- Hospital Oost-Limburg
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- De Keyzer, Dieter (författare)
- Hospital Oost-Limburg
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- Welp, Henryk (författare)
- University Hospital Münster
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- Maselli, Daniele (författare)
- S. Anna Hospital
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- Lichtenberg, Artur (författare)
- University Hospital of Düsseldorf
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- Ruggieri, Vito G. (författare)
- Robert Debré University Hospital
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- Biancari, Fausto (författare)
- Helsinki University Central Hospital,University of Turku,University of Oulu
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(creator_code:org_t)
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- Elsevier BV, 2021
- 2021
- Engelska 7 s.
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Ingår i: Journal of Cardiothoracic and Vascular Anesthesia. - : Elsevier BV. - 1053-0770 .- 1532-8422. ; 35:9, s. 2662-2668
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective: The optimal duration of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients affected by postcardiotomy cardiogenic shock (PCS) remains controversial. The present study was conducted to investigate the effect of VA-ECMO duration on hospital outcomes. Design: Retrospective analysis of an international registry. Setting: Multicenter study including 19 tertiary university hospitals. Participants: Between January 2010 and March 2018, data on PCS patients receiving VA-ECMO were retrieved from the multicenter PC-ECMO registry. Interventions: Patients were stratified according to the following different durations of VA-ECMO therapy: ≤three days, four-to-seven days, eight-to-ten days, and >ten days. Measurements and Main Results: A total of 725 patients, with a mean age of 62.9 ± 12.9 years, were included. The mean duration of VA-ECMO was 7.1 ± 6.3 days (range 0-39 d), and 39.4% of patients were supported for ≤three days, 29.1% for four-seven days, 15.3% for eight-ten days, and finally 20.7% for >ten days. A total of 391 (53.9%) patients were weaned from VA-ECMO successfully; however, 134 (34.3%) of those patients died before discharge. Multivariate logistic regression showed that prolonged duration of VA-ECMO therapy (four-seven days: adjusted rate 53.6%, odds ratio [OR] 0.28, 95% confidence interval [CI] 0.18-0.44; eight-ten days: adjusted rate 61.3%, OR 0.51, 95% CI 0.29-0.87; and >ten days: adjusted rate 59.3%, OR 0.49, 95% CI 0.31-0.81) was associated with lower risk of mortality compared with VA-ECMO lasting ≤three days (adjusted rate 78.3%). Patients requiring VA-ECMO therapy for eight-ten days (OR 1.96, 95% CI 1.15-3.33) and >10 days (OR 1.85, 95% CI 1.14-3.02) had significantly greater mortality compared with those on VA-ECMO for 4 to 7 days. Conclusions: PCS patients weaned from VA-ECMO after four-seven days of support had significantly less mortality compared with those with shorter or longer mechanical support.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- cardiac surgery
- duration
- ECMO
- extracorporeal membrane oxygenation
- survival
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- art (ämneskategori)
- ref (ämneskategori)
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Mariscalco, Giov ...
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El-Dean, Zein
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Yusuff, Hakeem
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Fux, Thomas
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Dell'Aquila, Ang ...
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Jónsson, Kristjá ...
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visa fler...
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Ragnarsson, Sigu ...
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Fiore, Antonio
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Dalén, Magnus
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di Perna, Dario
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Gatti, Giuseppe
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Juvonen, Tatu
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Zipfel, Svante
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Perrotti, Andrea
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Bounader, Karl
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Alkhamees, Khali ...
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Loforte, Antonio
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Lechiancole, And ...
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Pol, Marek
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Spadaccio, Crist ...
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Pettinari, Matte ...
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De Keyzer, Diete ...
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Welp, Henryk
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Maselli, Daniele
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Lichtenberg, Art ...
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Ruggieri, Vito G ...
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Biancari, Fausto
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Journal of Cardi ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet