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Antibiotic prophyla...
Antibiotic prophylaxis in posterior colporrhaphy does not reduce postoperative infection : a nationwide observational cohort study
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- Mörlin, Vilhelm (author)
- Karolinska University Hospital
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- Golmann, Denise (author)
- Karolinska Institute
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- Borgfeldt, Christer (author)
- Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Gynekologisk cancer, förebyggande av cancer och osteoporos,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Gynecological Cancer and Cancer prevention as well as prevention of Osteoporosis,Lund University Research Groups,Skåne University Hospital
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- Bergman, Ida (author)
- Karolinska Institutet,Karolinska Institute
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(creator_code:org_t)
- 2023
- 2023
- English.
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In: International Urogynecology Journal. - 0937-3462 .- 1433-3023. ; 34:11, s. 2791-2797
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Abstract
Subject headings
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- Introduction and hypothesis: The aim of this study was to explore if antibiotic prophylaxis prevents postoperative infection after a posterior colporrhaphy. Methods: In this register-based nationwide cohort study data were collected from the “The Swedish National Quality Register of Gynecological Surgery” (GynOp). Women 18 years or older who underwent a primary posterior colporrhaphy between 1 January 2015 and 31 December 2020 were included. Patients undergoing any concomitant prolapse procedure, mesh surgery, or incontinence procedure were excluded. The cohort was divided into two groups based on administration of antibiotic prophylaxis (n = 1,218) or not (n = 4,884). The primary outcome of this study was patient-reported infectious complication requiring antibiotic treatment. Secondary outcome measures included patient satisfaction and prolapse-related symptoms at 1 year postoperatively. Results: A total of 7,799 patients who underwent posterior colporrhaphy and met the inclusion criteria and did not meet the exclusion criteria were identified in the register database. Of these patients 6,102 answered the primary outcome question (79%). In the antibiotic prophylaxis group a total of 138 reported a postoperative infection (11%) and in the no antibiotic prophylaxis group the corresponding data were 520 (11%). There were no significant differences regarding either the primary or the secondary outcomes between the study groups. Conclusion: In this nationwide Swedish register study antibiotic prophylaxis was not associated with a reduced risk of postoperative infection after a posterior colporrhaphy.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Antibiotic prophylaxis
- Pelvic organ prolapse
- Perineorrhaphy
- Posterior colporrhaphy
- Postoperative infection
- Prolapse surgery
Publication and Content Type
- art (subject category)
- ref (subject category)
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