Sökning: WFRF:(Wahlberg Jeanette)
> (2020-2024) >
Current Management ...
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Bothou, ChristinaKlinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland,Univ Spital Zurich, Switzerland
(författare)
Current Management and Outcome of Pregnancies in Women With Adrenal Insufficiency : Experience from a Multicenter Survey
- Artikel/kapitelEngelska2020
Förlag, utgivningsår, omfång ...
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2020-05-19
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Oxford University Press,2020
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-108834
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-108834URI
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https://doi.org/10.1210/clinem/dgaa266DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-170003URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:144575464URI
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https://gup.ub.gu.se/publication/297312URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Funding Agencies:James A. Ruppe Career Development Award in EndocrinologyCatalyst Award for Advancing in Academics from Mayo Clinic
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Funding Agencies|Deutsche Forschungsgemeinschaft (DFG)German Research Foundation (DFG) [CRC/Transregio 205/1]; James A. Ruppe Career Development Award in Endocrinology; Catalyst Award for Advancing in Academics from Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) USA [K23DK121888]
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Context: Appropriate management of adrenal insufficiency (AI) in pregnancy can be challenging due to the rarity of the disease and lack of evidence-based recommendations to guide glucocorticoid and mineralocorticoid dosage adjustment.Objective: Multicenter survey on current clinical approaches in managing AI during pregnancy.Design: Retrospective anonymized data collection from 19 international centers from 2013 to 2019.Setting and patients: 128 pregnancies in 113 women with different causes of AI: Addison disease (44%), secondary AI (25%), congenital adrenal hyperplasia (25%), and acquired AI due to bilateral adrenalectomy (6%).Results: Hydrocortisone (HC) was the most commonly used glucocorticoid in 83% (97/117) of pregnancies. Glucocorticoid dosage was increased at any time during pregnancy in 73/128 (57%) of cases. In these cases, the difference in the daily dose of HC equivalent between baseline and the third trimester was 8.6 ± 5.4 (range 1-30) mg. Fludrocortisone dosage was increased in fewer cases (7/54 during the first trimester, 9/64 during the second trimester, and 9/62 cases during the third trimester). Overall, an adrenal crisis was reported in 9/128 (7%) pregnancies. Cesarean section was the most frequent mode of delivery at 58% (69/118). Fetal complications were reported in 3/120 (3%) and minor maternal complications in 15/120 (13%) pregnancies without fatal outcomes.Conclusions: This survey confirms good maternal and fetal outcome in women with AI managed in specialized endocrine centers. An emphasis on careful endocrine follow-up and repeated patient education is likely to have reduced the risk of adrenal crisis and resulted in positive outcomes.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Anand, GurpreetKlinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland,Univ Spital Zurich, Switzerland
(författare)
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Li, DingfengDivision of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA,Mayo Clin, MN 55905 USA
(författare)
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Kienitz, TinaEndocrinology in Charlottenburg, Berlin, Germany,Endocrinol Charlottenburg, Germany
(författare)
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Seejore, KhyatishaDepartment of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, Leeds, England,St James Univ Hosp, England
(författare)
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Simeoli, ChiaraDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy,Univ Federico II Napoli, Italy
(författare)
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Ebbehoj, AndreasDepartment of Clinical Medicine, Department of Endocrinology and Diabetes, Aarhus University, Aarhus, Denmark,Aarhus Univ, Denmark
(författare)
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Ward, Emma G.Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, Leeds, England,St James Univ Hosp, England
(författare)
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Paragliola, Rosa MariaUnit of Endocrinology, Università Cattolica del Sacro Cuore – Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy,Univ Cattolica Sacro Cuore Fdn Policlin Univ Agos, Italy
(författare)
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Ferrigno, RosarioDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy,Univ Federico II Napoli, Italy
(författare)
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Badenhoop, KlausDepartment of Internal Medicine I, Division of Endocrinology, Diabetes and Metabolism, University Hospital, Frankfurt, Germany,Univ Hosp, Frankfurt, Germany
(författare)
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Bensing, SophieKarolinska Institutet
(författare)
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Oksnes, MarianneEndocrinology in Charlottenburg, Berlin, Germany; Department of Clinical Science and K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Jonas Liesvei, Bergen, Norway,Endocrinol Charlottenburg, Germany; Univ Bergen, Norway; Univ Bergen, Norway
(författare)
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Esposito, DanielaGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xespda
(författare)
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Bergthorsdottir, Ragnhildur,1971Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xberag
(författare)
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Drake, WilliamDepartment of Endocrinology, St Bartholomew’s Hospital, London, UK,St Bartholomews Hosp, England
(författare)
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Wahlberg, Jeanette,1969-Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Endokrinmedicinska kliniken(Swepub:liu)jeawa98
(författare)
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Reisch, NicoleDepartment of Endocrinology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany
(författare)
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Hahner, StefanieDepartment of Internal Medicine I, Endocrinology and Diabetes Unit, University Hospital of Würzburg, University of Würzburg, Germany
(författare)
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Pearce, SimonTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK,Newcastle Univ, England
(författare)
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Trainer, PeterThe Christie NHS Foundation, MAHSC, Wilmslow Road, Manchester, England,Christie NHS Fdn, England
(författare)
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Etzrodt-Walter, GwendolinPraxis Dr. Etzrodt-Walter Endokrinologiezentrum Ulm, Ulm, Germany,Praxis Dr Etzrodt Walter Endokrinol Zentrum Ulm, Germany
(författare)
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Thalmann, Sébastien P.Ärztezentrum Sihlcity, Zurich, Switzerland
(författare)
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Sævik, Åse B.Department of Clinical Science and K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Jonas Liesvei, Bergen, Norway,Univ Bergen, Norway
(författare)
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Husebye, EysteinDepartment of Clinical Science and K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Jonas Liesvei, Bergen, Norway,Univ Bergen, Norway
(författare)
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Isidori, Andrea M.Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy,Sapienza Univ Rome, Italy
(författare)
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Falhammar, HenrikKarolinska Institutet
(författare)
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Meyer, GesineDepartment of Internal Medicine I, Division of Endocrinology, Diabetes and Metabolism, University Hospital, Frankfurt, Germany,Univ Hosp, Germany
(författare)
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Corsello, Salvatore M.Unit of Endocrinology, Università Cattolica del Sacro Cuore – Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy,Univ Cattolica Sacro Cuore Fdn Policlin Univ Agos, Italy
(författare)
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Pivonello, RosarioDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy,Univ Federico II Napoli, Italy
(författare)
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Murray, RobertDepartment of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, Leeds, England,St James Univ Hosp, England
(författare)
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Bancos, IrinaDivision of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA,Mayo Clin, MN 55905 USA
(författare)
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Quinkler, MarcusEndocrinology in Charlottenburg, Berlin, Germany,Endocrinol Charlottenburg, Germany
(författare)
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Beuschlein, FelixKlinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland; Department of Endocrinology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany,Univ Spital Zurich, Switzerland; Klinikum Univ Munchen, Germany
(författare)
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Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, SwitzerlandUniv Spital Zurich, Switzerland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Clinical Endocrinology and Metabolism: Oxford University Press105:80021-972X1945-7197
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- Av författaren/redakt...
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Bothou, Christin ...
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Anand, Gurpreet
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Li, Dingfeng
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Kienitz, Tina
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Seejore, Khyatis ...
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Simeoli, Chiara
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visa fler...
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Ebbehoj, Andreas
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Ward, Emma G.
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Paragliola, Rosa ...
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Ferrigno, Rosari ...
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Badenhoop, Klaus
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Bensing, Sophie
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Oksnes, Marianne
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Esposito, Daniel ...
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Bergthorsdottir, ...
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Drake, William
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Wahlberg, Jeanet ...
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Reisch, Nicole
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Hahner, Stefanie
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Pearce, Simon
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Trainer, Peter
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Etzrodt-Walter, ...
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Thalmann, Sébast ...
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Sævik, Åse B.
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Husebye, Eystein
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Isidori, Andrea ...
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Falhammar, Henri ...
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Meyer, Gesine
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Corsello, Salvat ...
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Pivonello, Rosar ...
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Murray, Robert
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Bancos, Irina
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Quinkler, Marcus
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Beuschlein, Feli ...
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