Association between hypersomnolence and the COVID-19 pandemic: The International COVID-19 Sleep Study (ICOSS).

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Fältnamn	Indikatorer	Metadata
000		04444naa a2200637 4500
001		oai:DiVA.org:uu-501462
003		SwePub
008		230509s2023 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5014622 URI
024	7	a https://doi.org/10.1016/j.sleep.2023.04.0242 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Sarkanen, Tomi4 aut
245	1 0	a Association between hypersomnolence and the COVID-19 pandemic :b The International COVID-19 Sleep Study (ICOSS).
264	1	b Elsevier,c 2023
338		a electronic2 rdacarrier
520		a BACKGROUND: The COVID-19 pandemic and related restriction measures have affected our daily life, sleep, and circadian rhythms worldwide. Their effects on hypersomnolence and fatigue remain unclear.METHODS: The International COVID-19 Sleep Study questionnaire which included items on hypersomnolence such as excessive daytime sleepiness (EDS), and excessive quantity of sleep (EQS), as well as sociodemographic factors, sleep patterns, psychological symptoms, and quality of life was distributed in 15 countries across the world from May to September in 2020.RESULTS: Altogether responses from 18,785 survey participants (65% women, median age 39 years) were available for analysis. Only 2.8% reported having had COVID-19. Compared to before the pandemic, the prevalence of EDS, EQS, and fatigue increased from 17.9% to 25.5%, 1.6%-4.9%, and 19.4%-28.3% amid the pandemic, respectively. In univariate logistic regression models, reports of having a COVID-19 were associated with EQS (OR 5.3; 95%-CI 3.6-8.0), EDS (2.6; 2.0-3.4), and fatigue (2.8; 2.1-3.6). In adjusted multivariate logistic regression, sleep duration shorter than desired (3.9; 3.2-4.7), depressive symptoms (3.1; 2.7-3.5), use of hypnotics (2.3; 1.9-2.8), and having reported COVID-19 (1.9; 1.3-2.6) remained strong predictors of EDS. Similar associations emerged for fatigue. In the multivariate model, depressive symptoms (4.1; 3.6-4.6) and reports of having COVID-19 (2.0; 1.4-2.8) remained associated with EQS.CONCLUSIONS: A large increase in EDS, EQS, and fatigue occurred due to the COVID-19 pandemic, and especially in self-reported cases of COVID-19. These findings warrant a thorough understanding of their pathophysiology to target prevention and treatment strategies for long COVID condition.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
653		a COVID-19
653		a Fatigue
653		a Hypersomnia
653		a ICOSS
653		a Pandemic
653		a Sleepiness
700	1	a Partinen, Markku4 aut
700	1	a Bjorvatn, Bjørn4 aut
700	1	a Merikanto, Ilona4 aut
700	1	a Benedict, Christian,c Docent,d 1976-u Uppsala universitet,Institutionen för farmaceutisk biovetenskap4 aut0 (Swepub:uu)chrbe136
700	1	a Nadorff, Michael R4 aut
700	1	a Bolstad, Courtney J4 aut
700	1	a Espie, Colin4 aut
700	1	a Matsui, Kentaro4 aut
700	1	a Chung, Frances4 aut
700	1	a Morin, Charles M4 aut
700	1	a Wing, Yun Kwok4 aut
700	1	a Penzel, Thomas4 aut
700	1	a Macêdo, Tainá4 aut
700	1	a Mota-Rolim, Sérgio4 aut
700	1	a Holzinger, Brigitte4 aut
700	1	a Plazzi, Giuseppe4 aut
700	1	a De Gennaro, Luigi4 aut
700	1	a Landtblom, Anne-Marieu Uppsala universitet,Institutionen för medicinska vetenskaper4 aut0 (Swepub:uu)annla922
700	1	a Inoue, Yuichi4 aut
700	1	a Sieminski, Mariuz4 aut
700	1	a Leger, Damien4 aut
700	1	a Dauvilliers, Yves4 aut
710	2	a Uppsala universitetb Institutionen för farmaceutisk biovetenskap4 org
773	0	t Sleep Medicined : Elsevierg 107, s. 108-115q 107<108-115x 1389-9457x 1878-5506
856	4	u https://doi.org/10.1016/j.sleep.2023.04.024y Fulltext
856	4	u https://uu.diva-portal.org/smash/get/diva2:1755647/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501462
856	4 8	u https://doi.org/10.1016/j.sleep.2023.04.024

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