Genetic architecture of subcortical brain structures in 38,851 individuals

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Fältnamn	Indikatorer	Metadata
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001		oai:DiVA.org:umu-166483
003		SwePub
008		200102s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:uu-397655
009		oai:prod.swepub.kib.ki.se:142268689
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1664832 URI
024	7	a https://doi.org/10.1038/s41588-019-0511-y2 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3976552 URI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1422686892 URI
040		a (SwePub)umud (SwePub)uud (SwePub)ki
041		a engb eng
042		9 SwePub
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100	1	a Satizabal, Claudia L.u UT Hlth San Antonio, Glenn Biggs Inst Alzheimers & Neurodegenerat Dis, San Antonio, TX 78229 USA;UT Hlth San Antonio, Dept Populat Hlth Sci, San Antonio, TX 78229 USA;Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA4 aut
245	1 0	a Genetic architecture of subcortical brain structures in 38,851 individuals
264		c 2019-10-21
264	1	b Nature Publishing Group,c 2019
338		a print2 rdacarrier
520		a Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
700	1	a Adams, Hieab H. H.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands;Erasmus MC, Dept Clin Genet, Rotterdam, Netherlands4 aut
700	1	a Hibar, Derrek P.u Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA4 aut
700	1	a White, Charles C.u Broad Inst, Cell Circuits Program, Cambridge, MA USA;Columbia Univ, Dept Neurol, Med Ctr, Ctr Translat & Computat Neuroimmunol, New York, NY USA,Natl Univ Singapore, Dept Pharmacol, Singapore, Singapore;Natl Univ Hlth Syst, Memory Aging & Cognit Ctr, Singapore, Singapore4 aut
700	1	a Knol, Maria J.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700	1	a Stein, Jason L.u Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA;Univ N Carolina, Dept Genet, Chapel Hill, NC 27515 USA;Univ N Carolina, UNC Neurosci Ctr, Chapel Hill, NC 27515 USA4 aut
700	1	a Scholz, Markusu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, Leipzig, Germany4 aut
700	1	a Sargurupremraj, Muralidharanu Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, Team Vintage, INSERM,UMR 1219, Bordeaux, France4 aut
700	1	a Jahanshad, Nedau Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA4 aut
700	1	a Roshchupkin, Gennady, Vu Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands;Erasmus MC, Dept Med Informat, Rotterdam, Netherlands4 aut
700	1	a Smith, Albert, Vu Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA;Univ Iceland, Fac Med, Reykjavik, Iceland;Iceland Heart Assoc, Kopavogur, Iceland4 aut
700	1	a Bis, Joshua C.u Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA4 aut
700	1	a Jian, Xueqiuu Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA4 aut
700	1	a Luciano, Michelleu Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Dept Psychol, Edinburgh, Midlothian, Scotland4 aut
700	1	a Hofer, Edithu Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria;Med Univ Graz, Inst Med Informat Stat & Documentat, Graz, Austria4 aut
700	1	a Teumer, Alexanderu Univ Med Greifswald, Inst Community Med, Greifswald, Germany4 aut
700	1	a van der Lee, Sven J.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700	1	a Yang, Jingyunu Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA;Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA4 aut
700	1	a Yanek, Lisa R.u Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Program, Baltimore, MD 21205 USA4 aut
700	1	a Lee, Tom, Vu Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA4 aut
700	1	a Li, Shuou Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA4 aut
700	1	a Hu, Yanhuiu Harvard Med Sch, Dept Genet, Boston, MA 02115 USA4 aut
700	1	a Koh, Jia Yuu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore4 aut
700	1	a Eicher, John D.u NHLBI, Div Intramural Res, Populat Sci Branch, Framingham, MA USA4 aut
700	1	a Desrivieres, Sylvaneu Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London, England4 aut
700	1	a Arias-Vasquez, Alejandrou Radboud Univ Nijmegen, Dept Cognit Neurosci, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Dept Psychiat, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Chauhan, Ganeshu Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, Team Vintage, INSERM,UMR 1219, Bordeaux, France;Indian Inst Sci, Ctr Brain Res, Bangalore, Karnataka, India4 aut
700	1	a Athanasiu, Laviniau Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway4 aut
700	1	a Rentera, Miguel E.u QIMR Berghofer Med Res Inst, Dept Genet & Computat Biol, Brisbane, Qld, Australia4 aut
700	1	a Kim, Sungeunu Indiana Univ Sch Med, Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA4 aut
700	1	a Hoehn, Davidu Max Planck Inst Psychiat, Munich, Germany4 aut
700	1	a Armstrong, Nicola J.u Murdoch Univ, Math & Stat, Perth, WA, Australia4 aut
700	1	a Chen, Qiangu Lieber Inst Brain Dev, Baltimore, MD USA4 aut
700	1	a Holmes, Avram J.u Yale Univ, Dept Psychol, New Haven, CT USA;Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA4 aut
700	1	a den Braber, Anouku Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands;Vrije Univ, Netherlands Twin Register, Amsterdam, Netherlands;Amsterdam Neurosci, Amsterdam, Netherlands;Vrije Univ Amsterdam, Dept Neurol, Amsterdam UMC, Amsterdam Neurosci,Alzheimer Ctr Amsterdam, Amsterdam, Netherlands4 aut
700	1	a Kloszewska, Iwonau Med Univ Lodz, Lodz, Poland4 aut
700	1	a Andersson, Micaelu Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB),Umeå centrum för funktionell hjärnavbildning (UFBI),Umea Univ, Dept Integrat Med Biol, Umea, Sweden;Umea Univ, Umea Ctr Funct Brain Imaging UFBI, Umea, Sweden4 aut0 (Swepub:umu)mian0001
700	1	a Espeseth, Thomasu Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Dept Psychol, Oslo, Norway4 aut
700	1	a Grimm, Oliveru Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Mannheim, Germany4 aut
700	1	a Abramovic, Lucijau Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands4 aut
700	1	a Alhusaini, Saudu Royal Coll Surgeons Ireland, Dublin, Ireland;Yale Sch Med, Dept Neurol, New Haven, CT USA4 aut
700	1	a Milaneschi, Yuriu Vrije Univ Amsterdam, Dept Psychiat, Amsterdam Neurosci, Med Ctr, Amsterdam, Netherlands4 aut
700	1	a Papmeyer, Martinau Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh, Midlothian, Scotland;Univ Bern, Univ Hosp Psychiat, Translat Res Ctr, Div Syst Neurosci Psychopathol, Bern, Switzerland4 aut
700	1	a Axelsson, Tomasu Uppsala universitet,Molekylär medicin,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)toaxe957
700	1	a Ehrlich, Stefanu Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA;Tech Univ Dresden, Div Psychol & Social Med & Dev Neurosci, Fac Med, Dresden, Germany;Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA USA4 aut
700	1	a Roiz-Santianez, Robertou Univ Cantabria IDIVAL, Univ Hosp Marques de Valdecilla, Sch Med, Dept Psychiat, Santander, Spain;Univ Cantabria IDIVAL, Univ Hosp Marques de Valdecilla, Sch Med, Dept Med, Santander, Spain;Ctr Invest Biomed Red Salud Mental, Santander, Spain4 aut
700	1	a Kraemer, Berndu Heidelberg Univ, Dept Gen Psychiat, Sect Expt Psychopathol & Neuroimaging, Heidelberg, Germany4 aut
700	1	a Håberg, Asta K.u Norwegian Univ Sci & Technol, Fac Med, Dept Neurosci, Trondheim, Norway;Trondheim Reg & Univ Hosp, St Olavs Hosp, Dept Radiol, Trondheim, Norway4 aut
700	1	a Jones, Hannah J.u Univ Bristol, Ctr Acad Mental Hlth, Bristol Med Sch, Populat Hlth Sci, Bristol, Avon, England;Univ Bristol, Bristol Med Sch, MRC Integrat Epidemiol Unit, Bristol, Avon, England;Univ Hosp Bristol NHS Fdn Trust, NIHR Bristol Biomed Res Ctr, Bristol, Avon, England;Univ Bristol, Bristol, Avon, England,Vrije Univ Amsterdam, Dept Psychiat, Amsterdam Neurosci, Med Ctr, Amsterdam, Netherlands4 aut
700	1	a Pike, G. Bruceu Univ Calgary, Dept Radiol, Calgary, AB, Canada;Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada4 aut
700	1	a Stein, Dan J.u Univ Cape Town, Dept Psychiat & Mental Hlth, Cape Town, South Africa;South African Med Res Council, Unit Risk & Resilience Mental Disorders, Cape Town, South Africa4 aut
700	1	a Stevens, Allisonu Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA USA4 aut
700	1	a Bralten, Janitau Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands,Univ Sydney, Brain & Mind Ctr, Sydney, NSW, Australia;Neurosci Res Australia, Sydney, NSW, Australia;Univ New South Wales, Sydney, NSW, Australia4 aut
700	1	a Vernooij, Meike W.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands,Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia4 aut
700	1	a Harris, Tamara B.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, NIH, Bethesda, MD 20892 USA4 aut
700	1	a Filippi, Irinau Paris Saclay Univ, INSERM, Res Unit Neuroimaging & Psychiat 1000, Gif Sur Yvette, France;Paris Descartes Univ, DIGITEO Labs, Gif Sur Yvette, France4 aut
700	1	a Witte, A. Veronicau Max Planck Inst Human Cognit & Brain Sci, Dept Neurol, Leipzig, Germany;Univ Leipzig, Fac Med, CRC Obes Mech 1052, Leipzig, Germany4 aut
700	1	a Guadalupe, Tuliou Int Max Planck Res Sch Language Sci, Nijmegen, Netherlands;Max Planck Inst Psycholinguist, Language & Genet Dept, Nijmegen, Netherlands4 aut
700	1	a Wittfeld, Katharinau Univ Med Greifswald, Dept Psychiat, Greifswald, Germany;German Ctr Neurodegenerat Dis, Greifswald, Germany4 aut
700	1	a Mosley, Thomas H.u Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA4 aut
700	1	a Becker, James T.u Univ Pittsburgh, Dept Psychol, Pittsburgh, PA 15260 USA;Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA;Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA4 aut
700	1	a Doan, Nhat Trung4 aut
700	1	a Hagenaars, Saskia P.u Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Dept Psychol, Edinburgh, Midlothian, Scotland4 aut
700	1	a Saba, Yasamanu Med Univ Graz, Gottfried Schatz Res Ctr Cell Signaling Metab & A, Res Unit Genet Epidemiol, Graz, Austria4 aut
700	1	a Cuellar-Partida, Gabrielu QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia4 aut
700	1	a Amin, Najafu Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands4 aut
700	1	a Hilal, Saimau Natl Univ Singapore, Dept Pharmacol, Singapore, Singapore;Natl Univ Hlth Syst, Memory Aging & Cognit Ctr, Singapore, Singapore4 aut
700	1	a Nho, Kwangsiku Indiana Univ Sch Med, Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA4 aut
700	1	a Mirza-Schreiber, Nazaninu Max Planck Inst Psychiat, Munich, Germany;German Res Ctr Environm Hlth, Inst Neurogen, Helmholtz Zentrum Munchen, Neuherberg, Germany4 aut
700	1	a Arfanakis, Konstantinosu Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA;IIT, Dept Biomed Engn, Chicago, IL 60616 USA;Rush Univ, Med Ctr, Dept Diagnost Radiol & Nucl Med, Chicago, IL 60612 USA4 aut
700	1	a Becker, Diane M.u Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Program, Baltimore, MD 21205 USA,Aarhus Univ, Ctr Integrated Sequencing, Aarhus, Denmark;Aarhus Univ, Dept Biomed, Aarhus, Denmark;Lundbeck Fdn Initiat Integrat Psychiat Res iPSYCH, Aarhus, Denmark;Karolinska Inst, Ctr Psychiat Res, Dept Clin Neurosci, Stockholm, Sweden;Stockholm Cty Council, Stockholm Hlth Care Serv, Stockholm, Sweden,UCL Queen Sq Inst Neurol, London, England;UCL Inst Neurol, Reta Lila Weston Inst, London, England;UCL Inst Neurol, Dept Mol Neurosci, London, England4 aut
700	1	a Ames, Davidu Univ Melbourne, Acad Unit Psychiat Old Age, Melbourne, Vic, Australia;Royal Melbourne Hosp, Natl Ageing Res Inst, Melbourne, Vic, Australia,Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA;Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA4 aut
700	1	a Goldman, Aaron L.u Lieber Inst Brain Dev, Baltimore, MD USA4 aut
700	1	a Lee, Phil H.u Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA;Harvard Med Sch, Boston, MA 02115 USA;Harvard Med Sch, Lurie Ctr Autism, Massachusetts Gen Hosp, Lexington, MA USA;Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Ctr Genom Med, Boston, MA 02114 USA;Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Boston, MA USA4 aut
700	1	a Boomsma, Dorret, Iu Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands;Vrije Univ, Netherlands Twin Register, Amsterdam, Netherlands;Amsterdam Neurosci, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands4 aut
700	1	a Lovestone, Simonu Univ Oxford, Dept Psychiat, Oxford, England;Kings Coll London, NIHR Dementia Biomed Res Unit, London, England4 aut
700	1	a Giddaluru, Sudheeru Univ Bergen, Dept Clin Sci, NORMENT, Bergen, Norway;Haukeland Hosp, Ctr Med Genet & Mol Med, Dr Einar Martens Res Grp Biol Psychiat, Bergen, Norway4 aut
700	1	a Le Hellard, Stephanieu Univ Bergen, Dept Clin Sci, NORMENT, Bergen, Norway;Haukeland Hosp, Ctr Med Genet & Mol Med, Dr Einar Martens Res Grp Biol Psychiat, Bergen, Norway4 aut
700	1	a Mattheisen, Manuelu Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands;Erasmus MC Sophia Childrens Hosp, Dept Child & Adolescent Psychiat Psychol, Rotterdam, Netherlands,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Dept Psychol, Edinburgh, Midlothian, Scotland;Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh, Midlothian, Scotland,Univ Calif San Diego, Ctr Multimodal Imaging & Genet, San Diego, CA 92103 USA;Univ Calif San Diego, Dept Cognit Sci, San Diego, CA 92103 USA;Univ Calif San Diego, Dept Neurosci, San Diego, CA 92103 USA;Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA;Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA,Douglas Mental Hlth Univ Inst, Cerebral Imaging Ctr, Montreal, PQ, Canada;McGill Univ, Dept Psychiat, Montreal, PQ, Canada;McGill Univ, Dept Biol & Biomed Engn, Montreal, PQ, Canada,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Dept Psychol, Edinburgh, Midlothian, Scotland;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland;Univ Edinburgh, UK Dementia Res Inst, Edinburgh, Midlothian, Scotland,Univ Calif Irvine, Dept Psychiat & Human Behav, Clin Translat Neurosci Lab, Irvine, CA 92717 USA;Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92717 USA,Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA USA,Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA;Kaiser Permanent Washington Hlth Res Inst, Seattle, WA USA;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA,Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Med & Mol Genet, Indianapolis, IN 46202 USA,Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands,Univ Bergen, Dept Clin Sci, NORMENT, Bergen, Norway;Haukeland Hosp, Ctr Med Genet & Mol Med, Dr Einar Martens Res Grp Biol Psychiat, Bergen, Norway,Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Neurol, Rotterdam, Netherlands,UCL Queen Sq Inst Neurol, London, England;Chalfont Ctr Epilepsy, Gerrards Cross, Bucks, England,Univ Bonn, Inst Human Genet, Bonn, Germany;Univ Bonn, Life & Brain Ctr, Dept Genom, Bonn, Germany,Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Leiden Univ, Leiden Acad Ctr Drug Res, Leiden, Netherlands,Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA;Baylor Coll Med, Dept Neurosci, Houston, TX 77030 USA;Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA;Texas Childrens Hosp, Jan & Dan Duncan Neurol Res Inst, Houston, TX 77030 USA,Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA,Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands4 aut
700	1	a Bohlken, Marc M.4 aut
700	1	a Kasperaviciute, Daliau UCL Queen Sq Inst Neurol, London, England;Chalfont Ctr Epilepsy, Gerrards Cross, Bucks, England4 aut
700	1	a Schmaal, Lianneu Univ Melbourne, Ctr Youth Mental Hlth, Melbourne, Vic, Australia;Orygen, Natl Ctr Excellence Youth Mental Hlth, Melbourne, Vic, Australia4 aut
700	1	a Lawrie, Stephen M.4 aut
700	1	a Agartz, Ingridu Karolinska Institutet4 aut
700	1	a Walton, Estheru Tech Univ Dresden, Div Psychol & Social Med & Dev Neurosci, Fac Med, Dresden, Germany;Univ Bath, Dept Psychol, Bath, Avon, England4 aut
700	1	a Tordesillas-Gutierrez, Dianau Ctr Invest Biomed Red Salud Mental, Santander, Spain;Valdecilla Biomed Res Inst IDIVAL, Neuroimaging Unit, Technol Facil, Santander, Spain4 aut
700	1	a Davies, Gareth E.u Avera Inst Human Genet, Sioux Falls, SD USA4 aut
700	1	a Shin, Jeanu Univ Toronto, Lospital Sick Children, Toronto, ON, Canada4 aut
700	1	a Ipser, Jonathan C.u Univ Cape Town, Dept Psychiat & Mental Hlth, Cape Town, South Africa4 aut
700	1	a Vinke, Louis N.u Boston Univ, Ctr Syst Neurosci, Boston, MA 02215 USA4 aut
700	1	a Hoogman, Martineu Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Jia, Tianyeu Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London, England4 aut
700	1	a Burkhardt, Ralphu Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, Leipzig, Germany;Univ Hosp Regensburg, Inst Clin Chem & Lab Med, Regensburg, Germany4 aut
700	1	a Klein, Mariekeu Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Crivello, Fabriceu Univ Bordeaux, Neurodegeneratives Dis Inst, CNRS UMR 5293, Bordeaux, France4 aut
700	1	a Janowitz, Deborahu Univ Med Greifswald, Dept Psychiat, Greifswald, Germany4 aut
700	1	a Carmichael, Owenu Pennington Biomed Res Ctr, 6400 Perkins Rd, Baton Rouge, LA 70808 USA4 aut
700	1	a Haukvik, Unn K.u Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, Dept Adult Psychiat, Oslo, Norway4 aut
700	1	a Aribisala, Benjamin S.u Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh, Midlothian, Scotland;Lagos State Univ, Dept Comp Sci, Ojo, Nigeria,Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA4 aut
700	1	a Schmidt, Helenau Med Univ Graz, Gottfried Schatz Res Ctr Cell Signaling Metab & A, Res Unit Genet Epidemiol, Graz, Austria4 aut
700	1	a Strike, Lachlan T.u QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia;Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia4 aut
700	1	a Cheng, Ching-Yuu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore4 aut
700	1	a Risacher, Shannon L.u Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA4 aut
700	1	a Puetz, Bennou Max Planck Inst Psychiat, Munich, Germany4 aut
700	1	a Fleischman, Debra A.u Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA;Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA;Rush Univ, Med Ctr, Dept Behav Sci, Chicago, IL 60612 USA4 aut
700	1	a Assareh, Amelia A.u Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia;Neurosci Res Australia, Sydney, NSW, Australia,Leiden Univ, Dept Psychiat, Med Ctr, Leiden, Netherlands;Leiden Univ, Leiden Inst Brain & Cognit, Med Ctr, Leiden, Netherlands,Univ Cape Town, Dept Psychiat & Mental Hlth, Cape Town, South Africa,Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway,Mind Res Network, Albuquerque, NM USA;LBERI, Albuquerque, NM USA;Georgia State Univ, Triinst Ctr Translat Res Neuroimaging & Data Sci, Atlanta, GA 30303 USA;Georgia State Univ, Dept Psychol, Univ Plaza, Atlanta, GA 30303 USA,Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA USA;Erasmus MC, Dept Psychiat, Rotterdam, Netherlands,Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands,Johns Hopkins Univ, Sch Med, Dept Med, GeneSTAR Res Program, Baltimore, MD 21205 USA4 aut
700	1	a Mattay, Venkata S.u Lieber Inst Brain Dev, Baltimore, MD USA;Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA;Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA4 aut
700	1	a Buckner, Randy L.u Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA;Harvard Univ, Dept Psychol, Ctr Brain Sci, 33 Kirkland St, Cambridge, MA 02138 USA4 aut
700	1	a Mecocci, Patriziau Univ Perugia, Dept Med, Sect Gerontol & Geriatr, Perugia, Italy4 aut
700	1	a Dale, Anders M.4 aut
700	1	a Cichon, Svenu Univ Basel, Dept Biomed, Div Med Genet, Basel, Switzerland;Univ Bonn, Inst Human Genet, Bonn, Germany;Res Ctr Julich, Inst Neurosci & Med Struct & Funct Org Brain INM, Julich, Germany4 aut
700	1	a Boks, Marco P.u Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands4 aut
700	1	a Matarin, Mar4 aut
700	1	a Penninx, Brenda W. J. H.u Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA,German Ctr Neurodegenerat Dis, Greifswald, Germany;Univ Med Greifswald, Inst Community Med, Sect Epidemiol Hlth Care & Community Hlth, Greifswald, Germany,Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands;Vrije Univ, Netherlands Twin Register, Amsterdam, Netherlands;Amsterdam Neurosci, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands,Freie Univ Berliepartment Psychiat & Psychotherap, Div Mind & Brain Res D, Berlin, Germany;Charite Univ Med Berlin, Berlin, Germany;Humboldt Univ, Berlin, Germany;Berlin Inst Hlth, Berlin, Germany4 aut
700	1	a Calhoun, Vince D.u Univ New Mexico, Dept ECE, Albuquerque, NM 87131 USA;Mind Res Network, Albuquerque, NM USA;LBERI, Albuquerque, NM USA;Georgia State Univ, Triinst Ctr Translat Res Neuroimaging & Data Sci, Atlanta, GA 30303 USA4 aut
700	1	a Chakravarty, M. Mallar4 aut
700	1	a Marquand, Andre F.u Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, Nijmegen, Netherlands4 aut
700	1	a Macare, Christineu Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London, England4 aut
700	1	a Masouleh, Shahrzad Kharabianu Max Planck Inst Human Cognit & Brain Sci, Dept Neurol, Leipzig, Germany;Res Ctr Julich, Inst Neurosci & Med Brain & Behav INM 7, Julich, Germany4 aut
700	1	a Oosterlaan, Jaapu Vrije Univ Amsterdam, Clin Neuropsychol Sect, Amsterdam, Netherlands;Univ Amsterdam, Amsterdam UMC, Amsterdam Reprod & Dev, Emma Neurosci Grp,Dept Pediat,Emma Childrens Hosp, Amsterdam, Netherlands4 aut
700	1	a Amouyel, Philippeu Univ Lille, RID AGE Risk Factors & Mol Determinants Aging Rel, LabEx DISTALZ U1167, Lille, France;Inserm U1167, Lille, France;Ctr Hosp Univ Lille, Lille, France;Inst Pasteur, Lille, France4 aut
700	1	a Hegenscheid, Katrinu Univ Med Greifswald, Inst Diagnost Radiol & Neuroradiol, Greifswald, Germany4 aut
700	1	a Rotter, Jerome, Iu Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles Biomed Res Inst & Pediat, Torrance, CA 90509 USA4 aut
700	1	a Schork, Andrew J.u Mental Hlth Ctr Sct Hans, Inst Biol Psychiat, Roskilde, Denmark;Translat Genom Res Inst, Neurogen Div, Phoenix, AZ USA4 aut
700	1	a Liewald, David C. M.4 aut
700	1	a de Zubicaray, Greig, Iu Queensland Univ Technol, Fac Hlth, Brisbane, Qld, Australia;Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia4 aut
700	1	a Wong, Tien Yinu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Acad Med Res Inst, Singapore, Singapore4 aut
700	1	a Shen, Liu Univ Penn, Dept Biostat Epidemiol & Informat, Philadelphia, PA 19104 USA4 aut
700	1	a Saemann, Philipp G.u Max Planck Inst Psychiat, Munich, Germany4 aut
700	1	a Brodaty, Henryu Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia;UNSW, Dementia Ctr Res Collaborat, Sydney, NSW, Australia4 aut
700	1	a Roffman, Joshua L.u Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA4 aut
700	1	a de Geus, Eco J. C.u Karolinska Institutet4 aut
700	1	a Tsolaki, Magdau Aristotle Univ Thessaloniki, Ahepa Univ Hosp, Dept Neurol 1, Thessaloniki, Greece4 aut
700	1	a Erk, Susanneu Freie Univ Berliepartment Psychiat & Psychotherap, Div Mind & Brain Res D, Berlin, Germany;Charite Univ Med Berlin, Berlin, Germany;Humboldt Univ, Berlin, Germany;Berlin Inst Hlth, Berlin, Germany4 aut
700	1	a van Eijk, Kristel R.u UMC Utrecht, Human Neurogenet Unit, Brain Ctr Rudolf Magnus, Utrecht, Netherlands4 aut
700	1	a Cavalleri, Gianpiero L.u Royal Coll Surgeons Ireland, Dept Mol & Cellular Therapeut, Dublin, Ireland4 aut
700	1	a van der Wee, Nic J. A.u NHLBI, Div Intramural Res, Populat Sci Branch, Framingham, MA USA4 aut
700	1	a McIntosh, Andrew M.4 aut
700	1	a Gollub, Randy L.u Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA;Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA USA;Harvard Med Sch, Boston, MA 02115 USA4 aut
700	1	a Bulayeva, Kazima B.u Dagestan State Univ, Dept Evolut & Genet, Makhachkala, Russia4 aut
700	1	a Bernard, Manonu Univ Toronto, Lospital Sick Children, Toronto, ON, Canada4 aut
700	1	a Richards, Jennifer S.u Radboud Univ Nijmegen, Dept Cognit Neurosci, Med Ctr, Nijmegen, Netherlands;Indian Inst Sci, Ctr Brain Res, Bangalore, Karnataka, India;Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands4 aut
700	1	a Himali, Jayandra J.4 aut
700	1	a Loeffler, Markusu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, Leipzig, Germany4 aut
700	1	a Rommelse, Nandau Radboud Univ Nijmegen, Dept Psychiat, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Karakter Child & Adolescent Psychiat Univ Ctr, Nijmegen, Netherlands4 aut
700	1	a Hoffmann, Wolfgang4 aut
700	1	a Westlye, Lars T.u Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway4 aut
700	1	a Hernandez, Maria C. Valdesu Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh, Midlothian, Scotland;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland4 aut
700	1	a Hansell, Narelle K.u QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia;Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia4 aut
700	1	a van Erp, Theo G. M.4 aut
700	1	a Wolf, Christianeu Univ Wurzburg, Dept Psychiat Psychosomat & Psychotherapy, Wurzburg, Germany4 aut
700	1	a Kwok, John B. J.u Radboud Univ Nijmegen, Dept Cognit Neurosci, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Karakter Child & Adolescent Psychiat Univ Ctr, Nijmegen, Netherlands4 aut
700	1	a Vellas, Brunou Univ Toulouse, Dept Internal Med, INSERM U1027, Toulouse, France;Univ Toulouse, Dept Geriatr Med, INSERM U1027, Toulouse, France4 aut
700	1	a Heinz, Andreasu Charite Univ Med Berlin, Dept Psychiat & Psychotherapy, Berlin, Germany4 aut
700	1	a Loohuis, Loes M. Olde4 aut
700	1	a Delanty, Normanu Royal Coll Surgeons Ireland, Dublin, Ireland;Beaumont Hosp, Neurol Div, Dublin, Ireland4 aut
700	1	a Ho, Beng-Choonu Univ Iowa, Dept Psychiat, Carver Coll Med, Iowa City, IA 52242 USA4 aut
700	1	a Ching, Christopher R. K.u Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA;UCLA, Sch Med, Interdept Neurosci Grad Program, Los Angeles, CA USA,Araya, Dept Neuroinformat, Tokyo, Japan;UCL, Inst Cognit Neurosci, London, England;Univ Sussex, Sch Psychol, Brighton, E Sussex, England4 aut
700	1	a Shumskaya, Elenau Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, Nijmegen, Netherlands,Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA4 aut
700	1	a Singh, Baljeetu Univ Calif Davis, Dept Neurol, Imaging Dementia & Aging Lab, Davis, CA 95616 USA4 aut
700	1	a Hofman, Albertu Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA4 aut
700	1	a van der Meer, Dennisu Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway;Maastricht Univ, Fac Hlth Med & Life Sci, Sch Mental Hlth & Neurosci, Maastricht, Netherlands4 aut
700	1	a Homuth, Georgu Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany4 aut
700	1	a Psaty, Bruce M.4 aut
700	1	a Bastin, Mark E.u Univ Edinburgh, Brain Res Imaging Ctr, Edinburgh, Midlothian, Scotland;Univ Edinburgh, Ctr Clin Brain Sci, Edinburgh, Midlothian, Scotland4 aut
700	1	a Montgomery, Grant W.u Univ Queensland, Inst Mol Biosci, Brisbane, Qld, Australia4 aut
700	1	a Foroud, Tatiana M.4 aut
700	1	a Reppermund, Simoneu Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia;UNSW Med, Dept Dev Disabil Neuropsychiat, Sch Psychiat, Sydney, NSW, Australia4 aut
700	1	a Hottenga, Jouke-Jan4 aut
700	1	a Simmons, Andrewu Kings Coll London, Biomed Res Unit Dementia, London, England;Kings Coll London, Inst Psychiat, Dept Neuroimaging, London, England;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Clin Geriatr, Stockholm, Sweden4 aut
700	1	a Meyer-Lindenberg, Andreasu Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Mannheim, Germany4 aut
700	1	a Cahn, Wiepkeu Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands4 aut
700	1	a Whelan, Christopher D.u Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA;Royal Coll Surgeons Ireland, Dublin, Ireland4 aut
700	1	a van Donkelaar, Marjolein M. J.4 aut
700	1	a Yang, Qiongu Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA4 aut
700	1	a Hosten, Norbertu Univ Med Greifswald, Inst Diagnost Radiol & Neuroradiol, Greifswald, Germany4 aut
700	1	a Green, Robert C.u Harvard Med Sch, Boston, MA 02115 USA;Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA4 aut
700	1	a Thalamuthu, Anbupalamu Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia4 aut
700	1	a Mohnke, Sebastianu Freie Univ Berliepartment Psychiat & Psychotherap, Div Mind & Brain Res D, Berlin, Germany;Charite Univ Med Berlin, Berlin, Germany;Humboldt Univ, Berlin, Germany;Berlin Inst Hlth, Berlin, Germany4 aut
700	1	a Pol, Hilleke E. Hulshoffu Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands4 aut
700	1	a Lin, Honghuangu Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02118 USA4 aut
700	1	a Jack, Clifford R., Jr.u Mayo Clin, Dept Radiol, Rochester, MN USA4 aut
700	1	a Schofield, Peter R.u Neurosci Res Australia, Sydney, NSW, Australia;UNSW, Sch Med Sci, Sydney, NSW, Australia4 aut
700	1	a Muehleisen, Thomas W.u Res Ctr Julich, Inst Neurosci & Med Struct & Funct Org Brain INM, Julich, Germany;Univ Basel, Dept Biomed, Basel, Switzerland;Heinrich Heine Univ Dusseldorf, Cecile & Oskar Vogt Inst Brain Res, Dusseldorf, Germany,Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Maillard, Paulineu Univ Calif Davis, Dept Neurol, Imaging Dementia & Aging Lab, Davis, CA 95616 USA4 aut
700	1	a Potkin, Steven G.u Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92717 USA4 aut
700	1	a Wen, Weiu Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Lab Neuro Imaging, Los Angeles, CA USA,Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA;Harvard Med Sch, Boston, MA 02115 USA;Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Ctr Genom Med, Boston, MA 02114 USA;Broad Inst MIT & Harvard, Stanley Ctr Psychiat Res, Boston, MA USA,Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA,Univ Calif San Francisco, Ctr Imaging Neurodegenerat Dis, San Francisco VA Med Ctr, San Francisco, CA 94143 USA;Univ Calif San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA 94143 USA4 aut
700	1	a Fletcher, Evanu Univ Calif Davis, Dept Neurol, Imaging Dementia & Aging Lab, Davis, CA 95616 USA4 aut
700	1	a Toga, Arthur W.4 aut
700	1	a Gruber, Oliveru Heidelberg Univ, Dept Gen Psychiat, Sect Expt Psychopathol & Neuroimaging, Heidelberg, Germany4 aut
700	1	a Huentelman, Matthewu Translat Genom Res Inst, Neurogen Div, Phoenix, AZ USA4 aut
700	1	a Smith, George Daveyu Univ Bristol, Bristol Med Sch, MRC Integrat Epidemiol Unit, Bristol, Avon, England4 aut
700	1	a Launer, Lenore J.u NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, NIH, Bethesda, MD 20892 USA,Broad Inst, Cell Circuits Program, Cambridge, MA USA;Columbia Univ, Dept Neurol, Med Ctr, Ctr Translat & Computat Neuroimmunol, New York, NY USA4 aut
700	1	a Nyberg, Lars,d 1966-u Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB),Umeå centrum för funktionell hjärnavbildning (UFBI),Umea Univ, Dept Integrat Med Biol, Umea, Sweden;Umea Univ, Umea Ctr Funct Brain Imaging UFBI, Umea, Sweden;Umea Univ, Radiat Sci, Umea, Sweden4 aut0 (Swepub:umu)lany0001
700	1	a Jönsson, Erik G.u Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway;Karolinska Inst, Ctr Psychiat Res, Dept Clin Neurosci, Stockholm, Sweden4 aut
700	1	a Crespo-Facorro, Benedictou Univ Cantabria IDIVAL, Univ Hosp Marques de Valdecilla, Sch Med, Dept Med, Santander, Spain;Ctr Invest Biomed Red Salud Mental, Santander, Spain4 aut
700	1	a Koen, Nastassjau Univ Cape Town, Dept Psychiat & Mental Hlth, Cape Town, South Africa;South African Med Res Council, Unit Risk & Resilience Mental Disorders, Cape Town, South Africa4 aut
700	1	a Greve, Douglas N.u Massachusetts Gen Hosp, Martinos Ctr Biomed Imaging, Charlestown, MA USA;Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02115 USA4 aut
700	1	a Uitterlinden, Andre G.u Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut
700	1	a Weinberger, Daniel R.u Lieber Inst Brain Dev, Baltimore, MD USA;Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA;Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA;Johns Hopkins Univ, Inst Genet Med, Sch Med, Baltimore, MD USA;Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21205 USA4 aut
700	1	a Steen, Vidar M.4 aut
700	1	a Fedko, Iryna O.u Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands;Vrije Univ, Netherlands Twin Register, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands4 aut
700	1	a Groenewold, Nynke A.4 aut
700	1	a Niessen, Wiro J.u Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands;Erasmus MC, Dept Med Informat, Rotterdam, Netherlands;Delft Univ Technol, Fac Appl Sci, Imaging Phys, Delft, Netherlands4 aut
700	1	a Toro, Robertou Inst Pasteur, Paris, France4 aut
700	1	a Tzourio, Christopheu CHU Bordeaux, Dept Neurol, Bordeaux, France4 aut
700	1	a Longstreth, William T., Jr.u Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA;Univ Washington, Dept Neurol, Seattle, WA 98195 USA4 aut
700	1	a Ikram, M. Kamran4 aut
700	1	a Smoller, Jordan W.4 aut
700	1	a van Tol, Marie-Joseu Univ Groningen, Univ Med Ctr Groningen, Cognit Neurosci Ctr, Groningen, Netherlands4 aut
700	1	a Sussmann, Jessika E.u Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh, Midlothian, Scotland4 aut
700	1	a Paus, Tomasu Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Toronto, ON, Canada;Univ Toronto, Dept Psychol, Toronto, ON, Canada;Univ Toronto, Dept Psychiat, Toronto, ON, Canada4 aut
700	1	a Lemaitre, Herveu Paris Saclay Univ, INSERM, Res Unit Neuroimaging & Psychiat 1000, Gif Sur Yvette, France;Paris Descartes Univ, DIGITEO Labs, Gif Sur Yvette, France4 aut
700	1	a Schroeter, Matthias L.u Univ Leipzig, LIFE Leipzig Res Ctr Civilizat Dis, Leipzig, Germany;Max Planck Inst Human Cognit & Brain Sci, Dept Neurol, Leipzig, Germany;Univ Clin Leipzig, Clin Cognit Neurol, Leipzig, Germany4 aut
700	1	a Mazoyer, Bernardu Univ Bordeaux, Neurodegeneratives Dis Inst, CNRS UMR 5293, Bordeaux, France4 aut
700	1	a Andreassen, Ole A.4 aut
700	1	a Holsboer, Florianu Max Planck Inst Psychiat, Munich, Germany;HMNC Brain Hlth, Munich, Germany4 aut
700	1	a Depondt, Chantalu Univ Libre Bruxelles, Dept Neurol, Hop Erasme, Brussels, Belgium4 aut
700	1	a Veltman, Dick J.u Vrije Univ Amsterdam, Dept Psychiat, Amsterdam Neurosci, Med Ctr, Amsterdam, Netherlands4 aut
700	1	a Turner, Jessica A.4 aut
700	1	a Pausova, Zdenkau Univ Toronto, Lospital Sick Children, Toronto, ON, Canada4 aut
700	1	a Schumann, Gunteru Kings Coll London, MRC SGDP Ctr, Inst Psychiat Psychol & Neurosci, London, England4 aut
700	1	a van Rooij, Daanu Radboud Univ Nijmegen, Dept Cognit Neurosci, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands4 aut
700	1	a Djurovic, Srdjanu Univ Bergen, Dept Clin Sci, NORMENT, Bergen, Norway;Oslo Univ Hosp, Dept Med Genet, Oslo, Norway4 aut
700	1	a Deary, Ian J.u Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Dept Psychol, Edinburgh, Midlothian, Scotland4 aut
700	1	a McMahon, Katie L.u Queensland Univ Technol, Fac Hlth, Brisbane, Qld, Australia;Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia4 aut
700	1	a Mueller-Myhsok, Bertramu Max Planck Inst Psychiat, Munich, Germany;Munich Cluster Syst Neurol SyNergy, Munich, Germany;Univ Liverpool, Inst Translat Med, Liverpool, Merseyside, England4 aut
700	1	a Brouwer, Rachel M.4 aut
700	1	a Soininen, Hilkkau Univ Eastern Finland, Inst Clin Med Neurol, Kuopio, Finland;Kuopio Univ Hosp, Neuroctr Neurol, Kuopio, Finland4 aut
700	1	a Pandolfo, Massimou Univ Libre Bruxelles, Dept Neurol, Hop Erasme, Brussels, Belgium4 aut
700	1	a Wassink, Thomas H.u Univ Iowa, Dept Psychiat, Carver Coll Med, Iowa City, IA 52242 USA4 aut
700	1	a Cheung, Joshua W.4 aut
700	1	a Wolfers, Thomas4 aut
700	1	a Martinot, Jean-Lucu Paris Saclay Univ, INSERM, Res Unit Neuroimaging & Psychiat 1000, Gif Sur Yvette, France;Paris Descartes Univ, DIGITEO Labs, Gif Sur Yvette, France4 aut
700	1	a Zwiers, Marcel P.u Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Ctr Cognit Neuroimaging, Nijmegen, Netherlands4 aut
700	1	a Nauck, Matthiasu Univ Med Greifswald, Inst Clin Chem & Lab Med, Greifswald, Germany;German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany4 aut
700	1	a Melle, Ingridu Oslo Univ Hosp, Div Mental Hlth & Addict, CoE NORMENT, Oslo, Norway;Univ Oslo, Inst Clin Med, CoE NORMENT, Oslo, Norway4 aut
700	1	a Martin, Nicholas G.u QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia4 aut
700	1	a Kanai, Ryota4 aut
700	1	a Westman, Ericu Karolinska Institutet4 aut
700	1	a Kahn, Rene S.u Univ Utrecht, Univ Med Ctr Utrecht, UMC Brain Ctr, Dept Psychiat, Utrecht, Netherlands;Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA4 aut
700	1	a Sisodiya, Sanjay M.4 aut
700	1	a White, Tonyau Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands;Erasmus MC Sophia Childrens Hosp, Dept Child & Adolescent Psychiat Psychol, Rotterdam, Netherlands4 aut
700	1	a Saremi, Arvinu Univ Southern Calif, Keck Sch Med, USC Mark & Mary Stevens Neuroimaging & Informat I, Imaging Genet Ctr, Los Angeles, CA USA4 aut
700	1	a van Bokhoven, Hansu Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Brunner, Han G.u Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Maastricht Univ, Dept Clin Genet, Med Ctr, Maastricht, Netherlands;GROW Sch Oncol & Dev Biol, Maastricht, Netherlands4 aut
700	1	a Voelzke, Henryu Univ Med Greifswald, Inst Community Med, Greifswald, Germany;German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany4 aut
700	1	a Wright, Margaret J.u Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia;Univ Queensland, Ctr Adv Imaging, Brisbane, Qld, Australia4 aut
700	1	a van't Ent, Dennisu Vrije Univ Amsterdam, Dept Biol Psychol, Amsterdam, Netherlands;Vrije Univ, Netherlands Twin Register, Amsterdam, Netherlands;Amsterdam Neurosci, Amsterdam, Netherlands;Vrije Univ Amsterdam Med Ctr, Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands4 aut
700	1	a Noethen, Markus M.4 aut
700	1	a Ophoff, Roel A.4 aut
700	1	a Buitelaar, Jan K.4 aut
700	1	a Fernandez, Guillnu Radboud Univ Nijmegen, Dept Cognit Neurosci, Med Ctr, Nijmegen, Netherlands;Indian Inst Sci, Ctr Brain Res, Bangalore, Karnataka, India4 aut
700	1	a Sachdev, Perminder S.u Univ New South Wales, Ctr Hlth Brain Ageing, Sch Psychiat, Sydney, NSW, Australia;Prince Wales Hosp, Neuropsychiat Inst, Sydney, NSW, Australia4 aut
700	1	a Rietschel, Marcellau Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Mannheim, Germany4 aut
700	1	a van Haren, Neeltje E. M.4 aut
700	1	a Fisher, Simon E.u Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Max Planck Inst Psycholinguist, Language & Genet Dept, Nijmegen, Netherlands4 aut
700	1	a Beiser, Alexa S.4 aut
700	1	a Francks, Clydeu Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands;Max Planck Inst Psycholinguist, Language & Genet Dept, Nijmegen, Netherlands4 aut
700	1	a Saykin, Andrew J.u Indiana Univ Sch Med, Ctr Neuroimaging Radiol & Imaging Sci, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Indiana Alzheimer Dis Ctr, Indianapolis, IN 46202 USA;Indiana Univ Sch Med, Med & Mol Genet, Indianapolis, IN 46202 USA4 aut
700	1	a Mather, Karen A.4 aut
700	1	a Romanczuk-Seiferth, Ninau Charite Univ Med Berlin, Dept Psychiat & Psychotherapy, Berlin, Germany4 aut
700	1	a Hartman, Catharina A.4 aut
700	1	a DeStefano, Anita L.u Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA4 aut
700	1	a Heslenfeld, Dirk J.u Vrije Univ Amsterdam, Dept Psychol, Amsterdam, Netherlands4 aut
700	1	a Weiner, Michael W.4 aut
700	1	a Walter, Henrik4 aut
700	1	a Hoekstra, Pieter J.u Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Groningen, Netherlands4 aut
700	1	a Nyquist, Paul A.4 aut
700	1	a Franke, Barbarau Radboud Univ Nijmegen, Dept Human Genet, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Dept Psychiat, Med Ctr, Nijmegen, Netherlands;Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands4 aut
700	1	a Bennett, David A.4 aut
700	1	a Grabe, Hans J.u Univ Med Greifswald, Dept Psychiat, Greifswald, Germany;German Ctr Neurodegenerat Dis, Greifswald, Germany4 aut
700	1	a Johnson, Andrew D.4 aut
700	1	a Chen, Christopher4 aut
700	1	a van Duijn, Cornelia M.4 aut
700	1	a Lopez, Oscar L.u Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA;Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA4 aut
700	1	a Fornage, Myriamu Univ Texas Hlth Sci Ctr Houston, Brown Fdn Inst Mol Med, Houston, TX 77030 USA;Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Houston, TX 77030 USA4 aut
700	1	a Wardlaw, Joanna M.4 aut
700	1	a Schmidt, Reinholdu Med Univ Graz, Dept Neurol, Clin Div Neurogeriatr, Graz, Austria4 aut
700	1	a DeCarli, Charlesu Univ Calif Davis, Ctr Neurosci, Dept Neurol, Sacramento, CA 95817 USA4 aut
700	1	a De Jager, Philip L.4 aut
700	1	a Villringer, Arnou Max Planck Inst Human Cognit & Brain Sci, Dept Neurol, Leipzig, Germany;Univ Leipzig, Fac Med, CRC Obes Mech 1052, Leipzig, Germany4 aut
700	1	a Debette, Stephanieu Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA;Univ Bordeaux, Bordeaux Populat Hlth Res Ctr, Team Vintage, INSERM,UMR 1219, Bordeaux, France;CHU Bordeaux, Dept Neurol, Bordeaux, France4 aut
700	1	a Gudnason, Vilmunduru Univ Iceland, Fac Med, Reykjavik, Iceland;Iceland Heart Assoc, Kopavogur, Iceland4 aut
700	1	a Medland, Sarah E.u QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia4 aut
700	1	a Shulman, Joshua M.4 aut
700	1	a Thompson, Paul M.4 aut
700	1	a Seshadri, Sudha4 aut
700	1	a Ikram, M. Arfan4 aut
710	2	a UT Hlth San Antonio, Glenn Biggs Inst Alzheimers & Neurodegenerat Dis, San Antonio, TX 78229 USA;UT Hlth San Antonio, Dept Populat Hlth Sci, San Antonio, TX 78229 USA;Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USAb Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Erasmus MC, Dept Radiol & Nucl Med, Rotterdam, Netherlands;Erasmus MC, Dept Clin Genet, Rotterdam, Netherlands4 org
773	0	t Nature Geneticsd : Nature Publishing Groupg 51:11, s. 1624-+q 51:11<1624-+x 1061-4036x 1546-1718
856	4	u https://www.duo.uio.no/bitstream/10852/75965/2/173831v1.full.pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166483
856	4 8	u https://doi.org/10.1038/s41588-019-0511-y
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397655
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:142268689

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